Purpose To evaluate intraocular pressure (IOP) variations after automated visual field examination in patients with primary open-angle glaucoma and in healthy subjects. Patients and Methods Intraocular pressure was measured in 49 patients (94 eyes) with primary open-angle glaucoma and in 13 healthy subjects (26 eyes) before and immediately after automated visual field examination. All patients had stable IOP and were using local medication to treat glaucoma. The visual field test was performed with a Humphrey 630 VF analyzer and the Central 30–2 full-threshold program. Results Mean IOP increased significantly in glaucomatous patients immediately after automated visual field examination (P < 0.01), and returned to pretest values after 1 hour (P = 0.2). Mean IOP variation was 2.38 (range, −6–11) mm Hg. In 42 (44.68%) glaucomatous eyes, IOP increased more than 2 mm Hg, with a mean increase of 5.5 mm Hg. Elderly glaucoma patients showed a significantly higher IOP rise than younger patients. No significant IOP variation was detected in healthy subjects. Conclusion Intraocular pressure varied significantly and tended to increase immediately after automated visual field examination in patients with primary open-angle glaucoma. Age seemed to contribute to these IOP changes, but other factors could be involved.

10.1097/00061198-200304000-00005

Cite

Citations (27)

Topical and systemic administration of carbonic anhydrase inhibitors

Acta Ophthalmologica Scandinavica (1999)

L. Taverniti Roberto Grenga C. De Gaetano

Carbonic anhydrase inhibitor

10.1111/j.1600-0420.1999.tb01145.x

Cite

Citations (0)

Ocular tension and pupil diameter effects of timolol 0.50% and pilocarpine 2% or 4% in association

Acta Ophthalmologica Scandinavica (1997)

L. Taverniti L. Voccia Lucrezia Amoroso C. De Stefano M Virno

Pilocarpine

10.1111/j.1600-0420.1997.tb00482.x

Cite

Citations (0)

The effects of 2% ibopamine eye drops on the intraocular pressure and pupil motility of patients with open-angle glaucoma.

PubMed (2004)

I Giuffr L. Taverniti Silvio Di Staso

Ibopamine is a prodrug of N-methyldopamine that has a non-cycloplegic mydriatic action due to its a-adrenergic properties and is able to induce, when topically given, a transient increase of intraocular pressure (IOP) in eyes with hydrodynamic disorders.This is a randomized, crossover, open-labeled, two- center study. Forty patients (20 open-angle glaucoma patients and 20 healthy subjects) were treated with ibopamine 2% eye drops and phenylephrine 10% eye drops.Ibopamine induced a significant increase in IOP only in glaucomatous eyes (p<0.001) without a significant hypertensive effect in normal eyes. Ibopamine and phenylephrine showed a similar mydriatic activity but ibopamine was able to induce an hypertensive effect only in glaucomatous eyes.The results confirm the use of ibopamine as provocative test in detection of hydrodynamic disorders.(Eur J Ophthalmol 2004; 14: #-13).

Phenylephrine

Mydriasis

10.5301/ejo.2008.5386

Cite

Citations (14)

Phacoemulsification and intraocular lens implant in eyes with primary angle-closure glaucoma: our experience

Acta Ophthalmologica Scandinavica (2002)

Silvio Di Staso Lelio Sabetti L. Taverniti Amy L. Aiello Italo Giuffrè

Primary angle-closure glaucoma (PACG) is a pathology connected with anatomic alterations of the eye, especially the anterior segment. PACG eyes are characterized by a smaller corneal diameter, a less deep anterior chamber, a greater anteroposterior diameter lens, a more anterior lens position and a reduced axial length. These particular conditions can lead to a pupillary block and iris deposition on the trabecular meshwork with peripheral synechiae formation and uncontrolled increase of intraocular pressure (IOP). A number of studies have shown evidence that PACG with pupillary block is more frequent in the 60–70 year age range and that in its pathogenesis the lens plays an important role. This study aims to verify the variations in the anatomical relationships between the anterior segment structures after phacoemulsification with IOL implant in the capsular sac and their influence on IOP. We considered two groups of patients: one of 12 members (10 women and 2 men), aged between 67 and 78 years, affected with PACG and cataract (group A) and a control of 12 members (7 women and 5 men) aged between 69 and 71 years, with no ocular pathology but cataract (group B). All the patients had phacoemulsification of the cataract surgery with soft acrylic IOL implant in the capsular sac. All were carried out by the same surgeon with access through clear cornea at the point equivalent to 12 h. All the patients were examined by the HUMPHREY model 840 50 MHz ultrabiomicroscope and the I3 HIRES 20 MHz. Measurements were made of anterior chamber depth, chamber angle width and IOP by Goldmann applanation tonometry, before the operation and at 1 month, 3, 6 and 9 months afterwards. Also measured before the operation were the lens thickness and the eyeball axial length (Table 1). Before the operation, group A anterior chamber depth (AC) was 1.87 ± 0.25 mm and at 9 months after the operation it was 3.92 ± 0.31 mm (P < 0.001), the mean increase thus being approximately 2 mm. The group B measures were, before the operation, a mean AC depth of 2.85 ± 0.36 mm and at 9 months after, 4.22 ± 0.21 (P < 0.001), being a mean increase of approximately 1.3 mm. Chamber angle widths were (at the same times) for group A 19.28 ± 5.3° and 36.1 ± 4.8° (P < 0.001), a mean approximate increase of 16.8° while for group B they were 30.25 ± 4.8° and 38.5 ± 4.7° (P > 0.001), a mean approximate increase of 8°. Before the operation, group A's mean IOP was 21.5 ± 2.6 mmHg and at 9 months 15.3 ± 2.1 mmHg without significant variation (P > 0.5). Lens thickness in group A was 5.08 ± 0.31 mm, in group B, 4.52 ± 0.33 (P < 0.001). Axial length in group A was 22.02 ± 0.86 mm and in group B was 23.18 ± 0.82 (P < 0.05) (Table 2). On the results obtained, we can confirm that the presence of a larger lens in an eyeball where the relationships between the CA anatomic structures are different to normal has an importance which is not negligible. Removal of the lens and the implant of a considerably smaller-sized IOL will in part go some way towards harmonizing those relationships and bring the eyeball into a state nearer to that physiologically normal. The fact that the IOP decreases significantly after IOL implant in the capsular sac of eyes affected by PACG confirms the opinions of other authors that, in these eyes, it is important to perform the lens operation before planning glaucoma surgery, always and in any case after a careful study of the anterior segment (Table 3).

IRIS (biosensor)

Corneal Endothelium

Anterior Eye Segment

10.1034/j.1600-0420.80.s236.6.x

Cite

Citations (28)