Davide Simion

University of Verona

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Daniel De Backer

Université Libre de Bruxelles

Alvise Martini

University of Verona

Nicola Menestrina

Ospedale Sacro Cuore Don Calabria

Leonardo Gottin

University of Verona

Jean‐Louis Vincent

Université Libre de Bruxelles

Lorena Torroni

University of Verona

Katia Donadello

University of Verona

Giovanna Occhipinti

Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione

Jacopo Weindelmayer

University of Verona

Selma Hetoja

University of Verona

Cooperative Institutions

Assistance Publique – Hôpitaux de Paris

Inserm

KU Leuven

Istituti di Ricovero e Cura a Carattere Scientifico

Institute of Cardiology

National and Kapodistrian University of Athens

Centre Hospitalier Universitaire de Liège

Sorbonne Université

University of Belgrade

Hospital Universitario Reina Sofía

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The “Weekday Effect” on Enhanced Recovery after Surgery Protocol for Gastrectomy

Digestive Surgery (2023)

Jacopo Weindelmayer Valentina Mengardo Lorena Torroni Maria Clelia Gervasi Selma Hetoja

Introduction: While enhanced recovery after surgery (ERAS) protocol demonstrated to improve outcomes after gastrectomy, some papers evidenced a detrimental effect on postoperative morbidity related to the “weekday effect.” We aimed to understand whether the day of gastrectomy could affect postoperative outcomes and compliance with ERAS items. Methods: We included all patients that underwent gastrectomy for cancer between January 2017 and September 2021. Cohort was divided considering the day of surgery: Early group (Monday–Wednesday) and Late group (Thursday–Friday). Compliance with protocol and postoperative outcomes were compared. Results: Two hundred twenty-seven patients were included in Early group, while 154 were in Late group. The groups were comparable in preoperative characteristics. No significant difference in pre/intraoperative and postoperative ERAS items’ compliance was apparent between Early and Late groups, with most items exceeding the 70% threshold. Median length of stay was 6.5 days and 6 days in Early and Late groups (p = 0.616), respectively. Morbidity was 50% in both groups, with severe complications that occurred in 13% of Early patients and 15% of Late patients. Ninety-day mortality was 2%, and it was similar between the two groups. Conclusions: In a center with a standardized ERAS protocol, the weekday of gastrectomy has no significant impact on the success of each ERAS item and on postoperative surgical and oncological outcomes.

Thursday

Cancer surgery

10.1159/000531022

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Citations (1)

Basic Principles of Oxygen Transport and Calculations

Jean‐Louis Vincent Pongdhep Theerawit Davide Simion

This chapter contains sections titled: Introduction Back to basics Effects of transfusion on cellular oxygenation The effects of transfusions on oxygen extraction The microcirculatory effects of blood transfusions Conclusion References

Oxygen transport

10.1002/9781444319583.ch17

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Citations (1)

Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis

Intensive Care Medicine (2022)

Gennaro De Pascale Massimo Antonelli Mieke Deschepper Kostoula Arvaniti Koen Blot

Pain medicine

10.1007/s00134-022-06883-y

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Citations (36)

Microvascular Perfusion Alterations Are Associated with a Poor Outcome in Patients with Severe Sepsis: A Multivariate Analysis in a Large Cohort.

Daniel De Backer Gustavo A. Ospina‐Tascón AP Neves Katia Donadello Davide Simion

10.1164/ajrccm-conference.2009.179.1_meetingabstracts.a4692

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Citations (0)

Poster session Friday 7 December - PM: Effect of systemic illnesses on the heart

European Heart Journal - Cardiovascular Imaging (2012)

Luminita Iliuță K. Uno A Ebihara Norihiro Hayashi Mayumi Chigira

10.1093/ehjci/jes266

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Supplementary Material for: The 'Weekday effect' on Enhanced Recovery After Surgery Protocol for Gastrectomy

Figshare (2023)

Jacopo Weindelmayer Valentina Mengardo Lorena Torroni Gervasi M.C.Selma Hetoja

Introduction: While Enhanced Recovery After Surgery (ERAS) protocol demonstrated to improve outcomes after gastrectomy, some papers evidenced a detrimental effect on postoperative morbidity related to the "weekday effect". We aimed to understand whether the day of gastrectomy could affect postoperative outcomes and compliance with ERAS items. Methods: We included all patients that underwent gastrectomy for cancer between January 2017 and September 2021. Cohort was divided considering the day of surgery: Early group (Monday-Wednesday) and Late group (Thursday-Friday). Compliance with protocol and postoperative outcomes were compared. Results: 227 patients were included in Early group, while 154 in Late group. The groups were comparable in pre-operative characteristics. No significant difference in pre/intraoperative and postoperative ERAS items' compliance was apparent between Early and Late groups, with most items exceeding the 70% threshold. Median length of stay was 6.5 days and 6 days in Early and Late groups (p=0.616), respectively. Morbidity was 50% in both groups, with severe complications that occurred in 13% of Early patients and 15% of Late patients. Ninety-day mortality was 2%, and it was similar between the two groups. Conclusions: In a Center with a standardized ERAS protocol, the weekday of gastrectomy has no significant impact on the success of each ERAS item and on postoperative surgical and oncological outcomes.

10.6084/m9.figshare.23608119

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Applanation tonometry application in ICU patients with acute cardiogenic edema

Critical Care (2010)

Nicola Menestrina Alvise Martini Davide Simion M. Dan Leonardo Gottin

The incidence of acute cardiogenic pulmonary edema (ACPE) is increasing and it is now one of the leading causes of morbidity and mortality in our society. As the global population of European countries is getting older, the impact of arterial stiffness is becoming more and more important in the pathophysiology of ACPE, besides coronary vascular disease and valvular disease. The aim of the study was to evaluate whether acute modifications in elastic artery distensibility can be involved in the pathogenesis of ACPE.

10.1186/cc8373

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Effects of fluids on microvascular perfusion in patients with severe sepsis

Intensive Care Medicine (2010)

Gustavo A. Ospina‐Tascón Ana Paula Neves Giovanna Occhipinti Katia Donadello Gustavo Büchele

Mean arterial pressure

Cardiac index

10.1007/s00134-010-1843-3

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Citations (291)

THE EFFECTS OF CRYSTALLOIDS AND ALBUMIN ON MICROCIRCULATORY ALTERATIONS IN PATIENTS WITH SEVERE SEPSIS