Introduction: Alzheimer's disease is a chronic brain disease that includes memory and language disorders. This disease, which is considered the most common cause of dementia worldwide, accounts for 60-80% of all dementia cases. Recent studies suggest that the cerebellum may play a role in cognitive functions as well as motor functions. Materials and Methods: The study was conducted on 40 Alzheimer's patients and 40 healthy individuals. In our study, volumetric evaluation of the cerebellum was performed. Results: As expected, significant differences were found in cerebellar volume reduction in AD patients compared to healthy controls. Significant volume increase was observed in some regions of the cerebellum in Alzheimer's patients compared to healthy individuals. Conclusion: The findings supported the role of the cerebellum in cognitive functions. Volume reductions may assist clinicians in making an early diagnosis of AD.
Abstract Purpose This study aimed to investigate the effect of anatomical variations in the sphenopalatine foramen and the lateral nasal wall on sphenopalatine foramen-related morphometric measurements. Methods Temporal bone multidetector computed tomography records of 153 patients were evaluated. Morphometric measurements were made between the fixed anatomical landmarks and the sphenopalatine foramen. Number, shape, localization variation of the sphenopalatine foramen, concha bullosa, and septum deviation were noted. Results No significant difference was detected between the right-left sides for all distances measured except SPF-CA and SPF-BL and most of the measurements were higher in males. In addition, statistical analysis of the obtained morphometric data was performed according to age groups. Classified the shape of the sphenopalatine foramen five types and reported that the most common irregularly shaped (37.3%). In our study, 91.2% single, 7.8% double, and 1% triple sphenopalatine foramen were detected. The location of sphenopalatine foramen was reported as the most common type I. No statistically significant relationship could be determined between morphometric data and septum deviation types. SPF-NF, SPF-ML, OSPF-ANS, and HSPF-ANS measurements were found to be significantly smaller in the presence of concha bullosa, whereas SPFA was found to be higher. Conclusion This study revealed a significant relationship between the morphometric measurements of the sphenopalatine foramen and concha bullosa, while septum deviation types did not affect morphometric results. For a safer and more effective surgery with prevention of iatrogenic complications, a surgeon should be aware of this correlation, especially in endoscopic sphenopalatine foramen approaches.
Most potential major complications in endoscopic sinus surgery are related to the ethmoid bone. To prevent complications, it is necessary to define the concept of a "dangerous ethmoid." The coronal multidetector computed tomography (MDCT) scans of a total of 271 patients, including 101 patients under 18 years old and 170 patients over 18 years old, were examined. For each patient, the depth of the olfactory fossa (DOF), the width of the olfactory fossa (WOF), the angle between the lateral lamella and the cribriform plate (LLCPA), the length of the lateral lamella (LLL), the distance between the nasal floor and the ethmoid roof (NFERL), and the width of the olfactory cleft (WOC) were recorded. The Keros and Gera types were determined. NFERL was found to be significantly higher in males across all age groups. WOC was significantly higher in males only under 18 years old. Only LLCPA was found to be significantly higher on the right side in both sexes. It was determined that NFERL increased with age, while WOC increased with age until 18. Keros type III and Gera type C, which are called dangerous types, were detected in 28 and 24 cases in total, respectively. The data obtained from significant anatomical landmarks in pediatric and adult cases provide useful information about the region in preoperative planning. The analysis results of the prevalence of Keros and Gera classifications allow the identification of high-risk anatomical conditions within the ethmoid.