Enver Yücel

Kartal Koşuyolu High Specialization Training and Research Hospital

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Barkın Kültürsay

Kartal Koşuyolu High Specialization Training and Research Hospital

Ci̇hangi̇r Kaymaz

Kartal Koşuyolu High Specialization Training and Research Hospital

İH

İbrahım Halıl Tanboğa

İstanbul Nişantaşı Üniversitesi

Ali Karagöz

Kartal Koşuyolu High Specialization Training and Research Hospital

Ali Karagöz

Kartal Koşuyolu High Specialization Training and Research Hospital

Berhan Keskin

Kartal Koşuyolu High Specialization Training and Research Hospital

ŞK

Şeyhmus Külahçıoğlu

Sağlık Bilimleri Üniversitesi

Emіne Altuntaş

Education Training And Research

Bayram Bağırtan

Education Training And Research

Hacer Ceren Tokgöz

Kartal Koşuyolu High Specialization Training and Research Hospital

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

Kartal Koşuyolu High Specialization Training and Research Hospital

University of Health Science

University of Health Sciences

Istanbul University

Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi

State Hospital

Atatürk University

Sivas State Hospital

Bursa Uludağ Üni̇versi̇tesi̇

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Naples Prognostic Score and Prediction of Left Ventricular Ejection Fraction in STEMI Patients

Angiology (2023)

Oğuzhan Birdal Levent Pay Emrah Aksakal Ahmet Çağdaş Yumurtaş Göksel Çinier

The Naples score is a new prognostic score developed according to inflammatory and nutritional status and frequently evaluated in cancer patients. The present study aimed to evaluate using the Naples prognostic score (NPS) to predict the development of decreased left ventricular ejection fraction (LVEF) after acute ST-segment elevation myocardial infarction (STEMI). The study has a multicenter and retrospective design and included 2280 patients with STEMI who underwent primary percutaneous coronary intervention (pPCI) between 2017 and 2022. All participants were divided into 2 groups according to their NPS. The relationship between these 2 groups and LVEF was evaluated. The low-Naples risk group (Group-1) included 799 patients, and the high-Naples risk group (Group-2) had 1481 patients. Hospital mortality, shock, and no-reflow rates were found to be higher in Group 2 compared with Group 1 (P < .001, P = .032, P = .004). The NPS was significantly inversely associated with discharge LVEF (B coefficient: -1.51, 95% CI-2.26; -.76, P = .001). NPS, a simple and easily calculated risk score, may help identify high-risk STEMI patients. To the best of our knowledge, the present study is the first to demonstrate the relationship between low LVEF and NPS in patients with STEMI.

10.1177/00033197231161903

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Tedavi Alan Hipertansif Olgularda Diürnal Kan Basıncı Değişikliğinin Efor Testi Sonrası Kalp Hızı Toparlanmasına Etkisi

Uludağ Üniversitesi Tıp Fakültesi Dergisi (2008)

Yusuf Aktürk Dilek Yeşilbursa Hakan Uçar Enver Yücel Osman Özdabakoğlu

Kan basinci (KB) kontrollu olan ve gece olculen kan basincinda yeterli dusme olmayan (non-dipper) hipertansiflerin egzersiz testi sonrasi kalp hizi toparlanmasinda gecikme gosterip gostermedigi incelendi. Tum hastalara Bruce protokolune gore maksimal efor testi uygulandi. Kalp hizi toparlanmasi (KHT), efor testi bittigindeki kalp hizi ile bir dakika sonraki kalp hizi arasindaki fark olarak tanimlandi. Sirkadiyen KB, 24 saatlik ambultuvar KB monitorizasyonu ile tespit edildi. Dipper KB profili olan hastalarin “non-dipper” olanlara gore gece ortalama sistolik ve diyastolik KB daha dusuk, sistolik ve diyastolik KB gece gunduz farki yuzdesi ise daha yuksekti. Dipper olanlarin KHT degerleri “non-dipper” bireylerden daha yuksekti (34.36±14.55/dak-32.48±8.60/dak, p=0.025). Ortalama gece sistolik-diyastolik KB degerleri ve KB gece gunduz farki yuzdesi ile KHT arasinda korelasyon yoktu. Sonuc olarak “Non-dipper” durum ile KHT gecikmesi arasinda istatistiksel olarak anlamli ancak klinik acidan cok da onemli olmayan bir iliski vardir. Bu bulgular “non-dipper” durumun duzeltilmesinden cok KB kontrolunun onemini gosterebilir.

Dipper

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A correlation of the ratio of left atrial volume to left ventricular ejection fraction in predicting atrial fibrillation in ischemic stroke

Journal of Surgery and Medicine (2023)

Songül Usalp Emіne Altuntaş Bayram Bağırtan Enver Yücel

Background/Aim: The enlargement of left atrial volume index (LAVI) in diastolic dysfunction (DD) may predispose one to atrial fibrillation (AF) and is an important etiological reason for ischemic stroke (IS). The ratio of LAVI increase to left ventricular ejection fraction (LVEF) is a new parameter, and this work investigates the correlation between DD parameters, LAVI, LAVI/LVEF ratio, and AF in patients with sinus rhythm presenting with IS. Methods: Here, 108 consecutive individuals who were diagnosed with IS were included in the case-control study. The patients were divided into two groups: Those with AF events on rhythm Holters (AF group, n=57) and those without (control group, n=51). LAVI was calculated from the apical four- and two-chamber views before the mitral valve was opened. LVEF was calculated by Simpson's method. Results: The mean age of the AF group was 73.9 (6.3) years, and the control group was 72.1 (3.9) years. Hypertension, diabetes mellitus, glucose, HbA1c, CHA₂DS₂-VASc score, and previous stroke were higher in the AF group (P<0.05). LAVI (35.7 [25.3-38.2] vs 29.6 [27.7-30.9], P<0.001), the LAVI/LVEF ratio (0.7 [0.63-0.77] vs 0.5 [0.50-0.54], P<0.001), and the E/é ratio (14.6 [13.9-15.0] vs 10.7 [9.0-11.8], P<0.001) were higher in patients with AF. Multivariable analyses showed that LAVI (OR:7.985, 95%CI [2.586-4.767], P<0.001) and the LAVI/LVEF ratio (OR:0.010, 95% CI [0.000-0.007], P=0.015) were potential independent risk factors for AF events. A positive correlation was found between the CHA₂DS₂-VASc score and LAVI (P=0.032, r=0.407) and LAVI/LVEF ratio (P=0.041, r=0.253). Conclusion: We concluded that the increase in LAVI and LAVI/LVEF ratio increases the risk of IS by increasing the tendency to AF. These parameters are useful in predicting IS.

Left atrial enlargement

Stroke

10.28982/josam.1063061

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Evaluation of the relationship between diabetic retinopathy and left atrial deformation parameters

The Egyptian Heart Journal (2022)

Şeyhmus Külahçıoğlu Işıl Kutlutürk Karagöz Yusuf Bilen Barkın Kültürsay Ravza Betül Akbaş

Abstract Background Left ventricular systolic dysfunction (LVSD) may develop without coronary artery disease, hypertension (HT), or valvular pathologies in patients with diabetes mellitus (DM), which is defined as diabetic cardiomyopathy (DCM) and its pathophysiology is still unclear. Diabetic retinopathy (DR) is a microvascular complication of DM, and patients with DR have increased risk for the development of heart failure (HF). Two-dimensional speckle tracking echocardiography (2D-STE) evaluates longitudinal deformation in left atrium (LA) myocardium and previous studies utilizing 2D-STE have revealed the detrimental effects of DM on LA functions. Although some studies have shown the association between DR and left ventricle (LV) systolic functions, as far as the researchers of this study investigated, there is no study evaluating the relationship between LA deformation parameters and DR. Hence, we aimed to investigate the relationship between the presence and the degree of DR and LA deformation parameters. Results LA deformation parameters were analyzed in terms of LA reservoir, conduit, and contractile functions according to the degree of DR. LA reservoir strain value was 14.2 ± 3.6 in normal retina group, 12.2 ± 4.1 in non-proliferative diabetic retinopathy (NPDR) group, and 13 ± 3.7 in proliferative diabetic retinopathy (PDR) group ( P = 0.04). LA contractile strain was 15.9 ± 6.8 in normal retina group, 13.1 ± 47.4 in NPDR group, and 9.9 ± 4.7 in PDR group ( P < 0.001). LA conduit strain was 30.1 ± 6.6 in normal retina group, 25.3 ± 6.5 in NPDR group, and 22.9 ± 4.9 in PDR group ( P < 0.001). Proportional odds regression for association between clinical data, echocardiographic parameters, and LA contractile strain function showed that increasing creatinine (from 0.7 to 1.0; OR 0.71; 95% CI 0.51–0.99; P = 0.04), DR presence (OR 0.24; 95% CI 0.11–0.50; P = 0.001), and increasing left atrial volume index (LAVI) (from 33.5 to 52.6; OR 0.62; 95% CI 0.43–0.89; P = 0.01) were associated with decreasing LA function; however, other variables indicated no association. Conclusions Our results showed the relationship between LA deformation parameters and DR, although microvascular involvement is not a certainly defined cardiovascular risk factor. Further prospective studies are needed to determine the clinical importance of DR presence and its degree for deformation parameters.

Diabetic Cardiomyopathy

Speckle tracking echocardiography

10.1186/s43044-022-00265-x

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Responsible Leadership and Higher Education

Routledge eBooks (2022)

Enver Yücel

In Chapter 13, Enver Yücel, the head of Bahçeşehir University (BAU) based in Turkey, considers higher education as a key fulcrum for responsible leadership and the realization of the United Nations (UN) Sustainable Development Goals (SDGs). This is underlined by the way in which many universities globally have aligned their mission with the SDGs, in a manner that adds value to their operation. This is illustrated at BAU, which has undertaken a wide span of initiatives in preparing people to participate as active citizens of the global community and in establishing collaboration among stakeholders for engagement in equal and inclusive education – all of which have progressed the UN SDGs.

10.4324/9781003129189-18

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Stabil anjina pektoris ile başvuran hastalarda koroner yavaş akımın klinik ve laboratuvar belirleyicileri

Celal Bayar Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi (2021)

Songül Usalp Emіne Altuntaş Bayram Bağırtan Enver Yücel Ali Bayraktar

Giriş ve Amaç: Koroner yatağın gecikmiş kontrast boyanmasıyla tanımlanan koroner yavaş akımın fenomeninin (KYA) patogenezinde endotelyal disfonksiyon olduğu düşünülmektedir. Bu çalışmamızda, stabil anjina pektoris ile başvuran ve yapılan koroner anjiografi sonrası KYA saptanan hastaların genel klinik özelliklerini ve risk faktörlerini bulmayı hedefledik. Gereç ve Yöntemler: Çalışmaya koroner anjiografi yapılarak KYA tespit edilen 121 hasta ve koroner damarlarında normal akım saptanan 164 hasta olmak üzere, toplam 285 hasta alındı. Bütün hastaların demografik ve klinik özellikleri geriye dönük olarak tarandı ve bu iki grup klinik özellikleri bakımından karşılaştırıldı. Bulgular: KYA olanların çoğu sigara içen, hipertrigliseridemisi olan ve çoğunlukla erkek cinsiyette olan hastalardı. Biyokimyasal parametreler, elektrokardiyografik ve ekokardiyografik özellikler açısından her iki grup arasında anlamlı farklılık izlenmedi. Çok değişkenli regresyon analizlerinde erkek cinsiyet (olasılık oranı [OO]:0.434, %95 güven aralığı : [0.252-0.856], p = 0.014) ve hipertrigliseridemi (OO : 1.001, %95 güven aralığı :[1.001 – 1.007], p = 0.035), KYA için bağımsız birer risk faktörü olarak saptandı. Sonuç: KYA, sigara içen, trigliserid değerleri yüksek ve erkek hastalarda daha sık idi. Erkek cinsiyet ve trigliserit yüksekliği KYA için bağımsız bir faktörü olarak bulundu. Trigliserid düzeyinin tahmini kesim değerinin > 138.5 mg/dL olması KYA ile ilişkili bulundu.

10.34087/cbusbed.932932

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Prognostic Impact of the Tricuspid Annular Plane Systolic Excursion/Pulmonary Arterial Systolic Pressure Ratio in Acute Pulmonary Embolism

The Anatolian Journal of Cardiology (2024)

Barkın Kültürsay Berhan Keskin Seda Tanyeri Şeyhmus Külahçıoğlu Aykun Hakgör

Currently available risk stratification models for acute pulmonary embolism (PE) include hemodynamic status, cardiac biomarkers, right ventricle (RV) dysfunction on imaging, and clinical scores. Focusing on the length-tension relationship of the ventricle might have a superior predictive capability over RV dysfunction in terms of mortality and classification of patients with acute PE. In this study, our hypothesis suggests that the tricuspid annular plane systolic excursion (TAPSE)/systolic pulmonary artery pressure (sPAP) ratio has superior predictive capability for in-hospital mortality in patients with acute PE compared to TAPSE or sPAP as distinct measures.

Risk Stratification

Excursion

10.14744/anatoljcardiol.2024.4110

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Fotoğraflarla Diyarbakır ve kültür varlıkları, 1928 = Photographs of Diyarbakır and its cultural assets, 1928

Kenan Erzurum Enver Yücel

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Enoksaparin Kullanımına Bağlı Spontan Retroperitoniyal Kanama

Turkiye Klinikleri Cardiovascular Sciences (2008)