Juan Antonio González-Barrios

Instituto Politécnico Nacional

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Daniel Martínez‐Fong

Instituto Politécnico Nacional

Bertha Alicia León‐Chávez

Benemérita Universidad Autónoma de Puebla

Guadalupe Soto-Rodríguez

Benemérita Universidad Autónoma de Puebla

Eduardo Brambila

Benemérita Universidad Autónoma de Puebla

Víctor Manuel Blanco-Álvarez

Benemérita Universidad Autónoma de Puebla

Celia Piña-Leyva

Institute for Social Security and Services for State Workers

Manuel Lara-Lozano

Center for Research and Advanced Studies of the National Polytechnic Institute

Constantino Tomás-Sanchez

Benemérita Universidad Autónoma de Puebla

Ana Karina Aguilar-Peralta

Benemérita Universidad Autónoma de Puebla

Alejandro Gonzalez-Vazquez

Benemérita Universidad Autónoma de Puebla

Cooperative Institutions

Instituto Politécnico Nacional

Universidad Nacional Autónoma de México

Center for Research and Advanced Studies of the National Polytechnic Institute

Benemérita Universidad Autónoma de Puebla

Institute for Social Security and Services for State Workers

Centro de Investigación en Materiales Avanzados

National Institute of Genomic Medicine

Instituto Nacional de Cancerología

Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

Mexican Social Security Institute

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Supplementary material 1 from: Calderón-Rosete G, González-Barrios JA, Piña-Leyva C, Moreno-Sandoval HN, Lara-Lozano M, Rodríguez-Sosa L (2021) Transcriptional identification of genes light-interacting in the extraretinal photoreceptors of the crayfish Procambarus clarkii. ZooKeys 1072: 107-127. https://doi.org/10.3897/zookeys.1072.73075

Gabina Calderón‐Rosete Juan Antonio González-Barrios Celia Piña-Leyva Hayde Nallely Moreno-Sandoval Manuel Lara-Lozano

Crayfish serve as a model for studying the effect of environmental lighting on locomotor activity and neuroendocrine functions. The effects of light on this organism are mediated differentially by retinal and extraretinal photoreceptors located in the cerebroid ganglion and the pleonal nerve cord. However, some molecular aspects of the phototransduction cascade in the pleonal extraretinal photoreceptors remain unknown. In this study, transcriptome data from the pleonal nerve cord of the crayfish Procambarus clarkii (Girard,1852) were analyzed to identify transcripts that potentially interact with phototransduction process. The Illumina MiSeq System and the pipeline Phylogenetically Informed Annotation (PIA) were employed, which places uncharacterized genes into pre-calculated phylogenies of gene families. Here, for the first time 62 transcripts identified from the pleonal nerve cord that are related to light-interacting pathways are reported; they can be classified into the following 11 sets: 1) retinoid pathway in vertebrates and invertebrates, 2) photoreceptor specification, 3) rhabdomeric phototransduction, 4) opsins 5) ciliary phototransduction, 6) melanin synthesis, 7) pterin synthesis, 8) ommochrome synthesis, 9) heme synthesis, 10) diurnal clock, and 11) crystallins. Moreover, this analysis comparing the sequences located on the pleonal nerve cord to eyestalk sequences reported in other studies reveals 94–100% similarity between the 55 common proteins identified. These results show that both retinal and pleonal non-visual photoreceptors in the crayfish equally expressed the transcripts involved in light detection. Moreover, they suggest that the genes related to ocular and extraocular light perception in the crayfish P. clarkii use biosynthesis pathways and phototransduction cascades commons.

Visual phototransduction

Procambarus clarkii

Opsin

10.3897/zookeys.1072.73075.suppl1

Cite

Citations (0)

Evidence in vitro of glial cell priming in the taiep rat

Brain Research (2003)

Bertha Alicia León‐Chávez Juan Antonio González-Barrios Araceli Ugarte Marco Antonio Meraz‐Ríos Daniel Martínez‐Fong

Priming (agriculture)

Neuroglia

10.1016/s0006-8993(02)04143-4

Cite

Citations (19)

Prophylactic Zinc Administration Combined with Swimming Exercise Prevents Cognitive-Emotional Disturbances and Tissue Injury following a Transient Hypoxic-Ischemic Insult in the Rat

Behavioural Neurology (2022)

Ana Karina Aguilar-Peralta Alejandro Gonzalez-Vazquez Constantino Tomás-Sanchez Víctor Manuel Blanco-Álvarez Daniel Martínez‐Fong

Exercise performance and zinc administration individually yield a protective effect on various neurodegenerative models, including ischemic brain injury. Therefore, this work was aimed at evaluating the combined effect of subacute prophylactic zinc administration and swimming exercise in a transient cerebral ischemia model. The prophylactic zinc administration (2.5 mg/kg of body weight) was provided every 24 h for four days before a 30 min common carotid artery occlusion (CCAO), and 24 h after reperfusion, the rats were subjected to swimming exercise in the Morris Water Maze (MWM). Learning was evaluated daily for five days, and memory on day 12 postreperfusion; anxiety or depression-like behavior was measured by the elevated plus maze and the motor activity by open-field test. Nitrites, lipid peroxidation, and the activity of superoxide dismutase (SOD) and catalase (CAT) were assessed in the temporoparietal cortex and hippocampus. The three nitric oxide (NO) synthase isoforms, chemokines, and their receptor levels were measured by ELISA. Nissl staining evaluated hippocampus cytoarchitecture and Iba-1 immunohistochemistry activated the microglia. Swimming exercise alone could not prevent ischemic damage but, combined with prophylactic zinc administration, reversed the cognitive deficit, decreased NOS and chemokine levels, prevented tissue damage, and increased Iba-1 (+) cell number. These results suggest that the subacute prophylactic zinc administration combined with swimming exercise, but not the individual treatment, prevents the ischemic damage on day 12 postreperfusion in the transient ischemia model.

Nissl body

NeuN

Elevated plus maze

Water maze

10.1155/2022/5388944

Cite

Citations (10)

Hypothalamic A11 Nuclei Regulate the Circadian Rhythm of Spinal Mechanonociception through Dopamine Receptors and Clock Gene Expression

Life (2022)

Celia Piña-Leyva Manuel Lara-Lozano Marina Rodríguez-Sánchez Guadalupe C. Vidal‐Cantú Ericka Barrientos Zavalza

Several types of sensory perception have circadian rhythms. The spinal cord can be considered a center for controlling circadian rhythms by changing clock gene expression. However, to date, it is not known if mechanonociception itself has a circadian rhythm. The hypothalamic A11 area represents the primary source of dopamine (DA) in the spinal cord and has been found to be involved in clock gene expression and circadian rhythmicity. Here, we investigate if the paw withdrawal threshold (PWT) has a circadian rhythm, as well as the role of the dopaminergic A11 nucleus, DA, and DA receptors (DR) in the PWT circadian rhythm and if they modify clock gene expression in the lumbar spinal cord. Naïve rats showed a circadian rhythm of the PWT of almost 24 h, beginning during the night-day interphase and peaking at 14.63 h. Similarly, DA and DOPAC's spinal contents increased at dusk and reached their maximum contents at noon. The injection of 6-hydroxydopamine (6-OHDA) into the A11 nucleus completely abolished the circadian rhythm of the PWT, reduced DA tissue content in the lumbar spinal cord, and induced tactile allodynia. Likewise, the repeated intrathecal administration of D1-like and D2-like DA receptor antagonists blunted the circadian rhythm of PWT. 6-OHDA reduced the expression of Clock and Per1 and increased Per2 gene expression during the day. In contrast, 6-OHDA diminished Clock, Bmal, Per1, Per2, Per3, Cry1, and Cry2 at night. The repeated intrathecal administration of the D1-like antagonist (SCH-23390) reduced clock genes throughout the day (Clock and Per2) and throughout the night (Clock, Per2 and Cry1), whereas it increased Bmal and Per1 throughout the day. In contrast, the intrathecal injection of the D2 receptor antagonists (L-741,626) increased the clock genes Bmal, Per2, and Per3 and decreased Per1 throughout the day. This study provides evidence that the circadian rhythm of the PWT results from the descending dopaminergic modulation of spinal clock genes induced by the differential activation of spinal DR.

PER2

PER1

10.3390/life12091411

Cite

Citations (3)

Transcriptional identification of genes light-interacting in the extraretinal photoreceptors of the crayfish Procambarus clarkii

ZooKeys (2021)

Gabina Calderón‐Rosete Juan Antonio González-Barrios Celia Piña-Leyva Hayde Nallely Moreno-Sandoval Manuel Lara-Lozano

Visual phototransduction

Procambarus clarkii

Eyestalk

Phototaxis

Opsin

10.3897/zookeys.1072.73075

Cite

Citations (1)

Subacute Zinc Administration and L-NAME Caused an Increase of NO, Zinc, Lipoperoxidation, and Caspase-3 during a Cerebral Hypoxia-Ischemia Process in the Rat

Oxidative Medicine and Cellular Longevity (2013)

Víctor Manuel Blanco-Álvarez Patricia López-Moreno Guadalupe Soto-Rodríguez Daniel Martínez‐Fong Hector Rubio

Zinc or L-NAME administration has been shown to be protector agents, decreasing oxidative stress and cell death. However, the treatment with zinc and L-NAME by intraperitoneal injection has not been studied. The aim of our work was to study the effect of zinc and L-NAME administration on nitrosative stress and cell death. Male Wistar rats were treated with ZnCl 2 (2.5 mg/kg each 24 h, for 4 days) and N- ω -nitro-L-arginine-methyl ester (L-NAME, 10 mg/kg) on the day 5 (1 hour before a common carotid-artery occlusion (CCAO)). The temporoparietal cortex and hippocampus were dissected, and zinc, nitrites, and lipoperoxidation were assayed at different times. Cell death was assayed by histopathology using hematoxylin-eosin staining and caspase-3 active by immunostaining. The subacute administration of zinc before CCAO decreases the levels of zinc, nitrites, lipoperoxidation, and cell death in the late phase of the ischemia. L-NAME administration in the rats treated with zinc showed an increase of zinc levels in the early phase and increase of zinc, nitrites, and lipoperoxidation levels, cell death by necrosis, and the apoptosis in the late phase. These results suggest that the use of these two therapeutic strategies increased the injury caused by the CCAO, unlike the alone administration of zinc.

10.1155/2013/240560

Cite

Citations (11)

Taurine Increases Zinc Preconditioning-Induced Prevention of Nitrosative Stress, Metabolic Alterations, and Motor Deficits in Young Rats following Intrauterine Ischemia

Oxidative Medicine and Cellular Longevity (2021)

Alejandro Gonzalez-Vazquez Ana Karina Aguilar-Peralta Constantino Tomás-Sanchez Víctor Manuel Blanco-Álvarez Daniel Martínez‐Fong

Oxygen deprivation in newborns leads to hypoxic‐ischemic encephalopathy, whose hallmarks are oxidative/nitrosative stress, energetic metabolism alterations, nutrient deficiency, and motor behavior disability. Zinc and taurine are known to protect against hypoxic‐ischemic brain damage in adults and neonates. However, the combined effect of prophylactic zinc administration and therapeutic taurine treatment on intrauterine ischemia‐ (IUI‐) induced cerebral damage remains unknown. The present work evaluated this issue in male pups subjected to transient IUI (10 min) at E17 and whose mothers received zinc from E1 to E16 and taurine from E17 to postnatal day 15 (PND15) via drinking water. We assessed motor alterations, nitrosative stress, lipid peroxidation, and the antioxidant system comprised of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx). Enzymes of neuronal energetic pathways, such as aspartate aminotransferase (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH), were also evaluated. The hierarchization score of the protective effect of pharmacological strategies (HSPEPS) was used to select the most effective treatment. Compared with the IUI group, zinc, alone or combined with taurine, improved motor behavior and reduced nitrosative stress by increasing SOD, CAT, and GPx activities and decreasing the GSSG/GSH ratio in the cerebral cortex and hippocampus. Taurine alone increased the AST/ALT, LDH/ALT, and AST/LDH ratios in the cerebral cortex, showing improvement of the neural bioenergetics system. This result suggests that taurine improves pyruvate, lactate, and glutamate metabolism, thus decreasing IUI‐caused cerebral damage and relieving motor behavior impairment. Our results showed that taurine alone or in combination with zinc provides neuroprotection in the IUI rat model.

10.1155/2021/6696538

Cite

Citations (7)

Carbohydrate Intake Modulates the Effect of the ABCA1 -R230C Variant on HDL Cholesterol Concentrations in Premenopausal Women

Journal of Nutrition (2011)

Sandra Romero‐Hidalgo Teresa Villarreal‐Molina Juan Antonio González-Barrios Samuel Canizales‐Quinteros Martha Eunice Rodríguez-Arellano

10.3945/jn.111.152421

Cite

Citations (18)

Mycobacterium tuberculosis as a cause of mandibular osteomyelitis in a young woman: a case report

Journal of Medical Case Reports (2016)

Jorge Téllez-Rodríguez Rubi Lopez-Fernandez Rodolfo Rodríguez‐Jurado Hayde Nallely Moreno-Sandoval Francisco Martínez‐Pérez

Tuberculosis is considered an emerging disease worldwide; in the last 10 years, its incidence has increased to more than 9.6 million cases of active tuberculosis. In 2014, it resulted in 1.5 million patient deaths. However, oral presentation with bone involvement occurs in less than 3% of all reported cases and rarely arouses clinical suspicion on initial presentation. A 15-year-old Mexican girl who had a previous diagnosis of neurofibromatosis presented to our hospital with pain and swelling in the region of the left mandibular body since November 2011. A clinical examination revealed pain in the mandibular region, a mass of soft consistency that seemed to involve bone, and a fistula with discharge of intraoral purulent material. Additionally, tachycardia and hyperthermia were observed. The left submental and submandibular regions had a 12-cm-diameter swelling, which was well-delineated and nonerythematous. The final diagnosis was established by real-time polymerase chain reaction. The final diagnosis of rare cases of tuberculous osteomyelitis in the jaw can be established by deoxyribonucleic acid (DNA) identification of Mycobacterium tuberculosis in the lesion. Simple and fast complementary diagnosis by real-time polymerase chain reaction is a fundamental approach to establishing early and effective pharmacological and surgical treatment.

Pericoronitis

Periosteal reaction

Presentation (obstetrics)

10.1186/s13256-016-1118-x

Cite

Citations (10)

Dual targeting of ANGPT1 and TGFBR2 genes by miR-204 controls angiogenesis in breast cancer

Scientific Reports (2016)

Ali Flores‐Pérez Laurence A. Marchat Sergio Rodrı́guez-Cuevas Verónica Bautista‐Piña Alfredo Hidalgo‐Miranda

Abstract Deregulated expression of microRNAs has been associated with angiogenesis. Studying the miRNome of locally advanced breast tumors we unsuspectedly found a dramatically repression of miR-204, a small non-coding RNA with no previous involvement in tumor angiogenesis. Downregulation of miR-204 was confirmed in an independent cohort of patients and breast cancer cell lines. Gain-of-function analysis indicates that ectopic expression of miR-204 impairs cell proliferation, anchorage-independent growth, migration, invasion, and the formation of 3D capillary networks in vitro . Likewise, in vivo vascularization and angiogenesis were suppressed by miR-204 in a nu/nu mice model. Genome-wide profiling of MDA-MB-231 cells expressing miR-204 revealed changes in the expression of hundred cancer-related genes. Of these, we focused on the study of pro-angiogenic ANGPT1 and TGFβR2. Functional analysis using luciferase reporter and rescue assays confirmed that ANGPT1 and TGFβR2 are novel effectors downstream of miR-204. Accordingly, an inverse correlation between miR-204 and ANGPT1/TGFβR2 expression was found in breast tumors. Knockdown of TGFβR2, but not ANGPT1, impairs cell proliferation and migration whereas inhibition of both genes inhibits angiogenesis. Taken altogether, our findings reveal a novel role for miR-204/ANGPT1/TGFβR2 axis in tumor angiogenesis. We propose that therapeutic manipulation of miR-204 levels may represent a promising approach in breast cancer.

Ectopic expression

10.1038/srep34504

Cite

Citations (71)