Sasse

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[The acridine orange test. A new parameter in assessing the fertilizing capacity of spermatozoa].

PubMed (1989)

K. Sterzik B. Rosenbusch Sasse Eva Maria Wild W Hütter

Simultaneously with in vitro fertilization (IVF), the acridine orange (AO) test was performed on 51 patients according to the method of Tejada et al. This test allows a differentiation of spermatozoa with intact (double-stranded) and denatured (single-sanded) DNA. A significant relationship was demonstrated between the percentage of green-fluorescing (intact) sperm and the results of IVF. For both, the groups with (n = 40) and without (n = 11) fertilization of human eggs, a positive correlation was found between AO-test and sperm motility, and AO-test and normal sperm morphology.

Acridine orange

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Citations (3)

[Differential effects of GnRH analogs on androgen concentrations in females].

PubMed (1991)

Ulrich Wirth Rossmanith Wg Sasse C Lauritzen

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A comparative study on the suppression of peritoneal adhesion formation in the rat.

PubMed (1985)

Colin Marais Sasse Peter F. McComb Gomel

The importance of periadnexal adhesions as cause in female infertility is widely recognized. The incidence of salpingo-ovariolysis (in the absence of tubal obstruction) has been reported as being 35% of the surgical procedures to promote fertility. In addition, one of the important causes of failure of reconstructive fertility surgery is related to postoperative adhesions (either reformed of formed de novo). Adhesions may encapsulate the ovary and/or the terminal end of the oviduct; they may disturb the physiologic spatial, relationship between the fimbriae and ovary and thus impair ovum pick up. Adhesions may also disturb ovarian function decreasing the number of ovulations. The importance of postoperative adhesions is evident also by the vast numbers of studies, published on this subject in the last decade.

Oviduct

Female infertility

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Citations (2)

[Cytogenetics of unfertilized or undivided oocytes within the scope of in vitro fertilization: relation to the kind of hormonal stimulation].

PubMed (1993)

B. Rosenbusch K. Sterzik Sasse Mahmoud Djalali

A cytogenetic analysis could be performed on 343 out of 566 oocytes which remained unfertilized or uncleaved during our in vitro fertilization (IVF) programme. The results were analyzed in relation to the kind of ovarian stimulation by classification of the patients into two groups: treatment with human menopausal gonadotropin (hMG) or treatment with clomiphene citrate (CC). There was no significant difference for the total rates of abnormal oocytes (hMG: 28.6%, CC: 32.2%), the rates of aneuploidy (hMG: 14.4%, CC: 16.9%), and the rates of hyperhaploidy (hMG: 3.9%, CC: 8.5%). These results suggest that the kind of medication for induction of multiple follicular growth does not influence the rate of cytogenetic anomalies in human oocytes.

Gonadotropin

Menotropins

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