Bing‐Ying Liu

Shaanxi University of Science and Technology

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Chao‐Hua Xue

Shaanxi University of Science and Technology

Xiao-Jing Guo

Fujian Medical University

Huidi Wang

Shaanxi University of Science and Technology

Meng-Chen Huang

Southwest University of Science and Technology

Fuquan Deng

Shaanxi University of Science and Technology

Chao‐Qun Ma

Shaanxi University of Science and Technology

Shun-Tian Jia

Shaanxi University of Science and Technology

Xihui Sheng

Beijing University of Agriculture

Jun Cheng

Northwest Institute For Non-Ferrous Metal Research

Xiangguo Wang

Beijing University of Agriculture

Cooperative Institutions

Shaanxi University of Science and Technology

China Agricultural University

Chinese Academy of Sciences

Beijing University of Agriculture

Huazhong University of Science and Technology

Fudan University

Chinese Academy of Agricultural Sciences

Soochow University

China XD Group (China)

University of Chinese Academy of Sciences

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Involvement of PKCε in FSH-induced connexin43 phosphorylation and oocyte maturation in mouse

Biology Open (2018)

Han Cai Bing‐Ying Liu Tingting Yang Yi Yang Jinrui Xu

Gap junctions (GJs) are indispensable for communication between cumulus cells (CCs) and oocytes in coordinating the gonadotropin-induced meiotic maturation of oocytes. Of all proteins that constitute GJs, phosphorylated connexin43 (pCx43) is vital for mediating the actions of gonadotropins. In this study, the mechanism of Cx43 phosphorylation in response to follicle stimulating hormone (FSH) stimulation was examined using an in vitro model of mouse cumulus-oocyte complexes (COCs). The results confirmed that Cx43 phosphorylation occurred twice during FSH treatment. Importantly, the second Cx43 phosphorylation was closely related to cAMP level reduction within oocytes, which initiated oocyte maturation. Exploration of the underlying mechanism revealed that the CC-specific protein kinase C ε (PKCε) level was upregulated by FSH stimulation. PKCε was a kinase downstream from mitogen-activated protein kinase (MAPK) and was responsible for Cx43 phosphorylation. Interestingly, MAPK was involved in both Cx43 phosphorylation processes, while PKCε was only involved in the second. In conclusion, PKCε-mediated MAPK signals might contribute to Cx43 phosphorylation in CCs during FSH-induced oocyte meiotic resumption. Our findings contribute to a better understanding of the molecular regulation mechanism of oocyte maturation in response to FSH in vitro.

10.1242/bio.034678

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Citations (8)

Bioinspired Superhydrophobic All‐In‐One Coating for Adaptive Thermoregulation

Advanced Materials (2024)

Bing‐Ying Liu Jiawei Wu Chao‐Hua Xue Yijun Zeng Jun Liang

The development of scalable and passive coatings that can adapt to seasonal temperature changes while maintaining superhydrophobic self-cleaning functions is crucial for their practical applications. However, the incorporation of passive cooling and heating functions with conflicting optical properties in a superhydrophobic coating is still challenging. Herein, an all-in-one coating inspired by the hierarchical structure of a lotus leaf that combines surface wettability, optical structure, and temperature self-adaptation is obtained through a simple one-step phase separation process. This coating exhibits an asymmetrical gradient structure with surface-embedded hydrophobic SiO

Superhydrophobic coating

10.1002/adma.202400745

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Citations (26)

Easily Established and Multifunctional Synthetic Nanobody Libraries as Research Tools

International Journal of Molecular Sciences (2022)

Bing‐Ying Liu Daiwen Yang

Nanobodies, or VHHs, refer to the antigen-binding domain of heavy-chain antibodies (HCAbs) from camelids. They have been widely used as research tools for protein purification and structure determination due to their small size, high specificity, and high stability, overcoming limitations with conventional antibody fragments. However, animal immunization and subsequent retrieval of antigen-specific nanobodies are expensive and complicated. Construction of synthetic nanobody libraries using DNA oligonucleotides is a cost-effective alternative for immunization libraries and shows great potential in identifying antigen-specific or even conformation-specific nanobodies. This review summarizes and analyses synthetic nanobody libraries in the current literature, including library design and biopanning methods, and further discusses applications of antigen-specific nanobodies obtained from synthetic libraries to research.

Biopanning

Single-domain antibody

10.3390/ijms23031482

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Fabrication of Impact-Resistant and Wear-Recoverable Superhydrophobic Surfaces

ACS Omega (2019)

Chao‐Hua Xue Huidi Wang Zhanyou Ji Xiao-Jing Guo Bing‐Ying Liu

Robustness of superhydrophobic materials has been gradually taken into consideration for practical applications; however, little attention has been paid to the impact resistance of the superhydrophobicity of the materials. The present study demonstrated a new route for improving the mechanical durability, especially the impact resistance, of the superhydrophobic materials. First, poly(styrene-co-butadiene)/poly(ethylene-vinyl acetate) (SBR/EVA) composite monoliths with microscale cellular structures were manufactured by vulcanization-foaming processes. Then the composite monoliths were treated with sandpaper to create nanostructures above the revealed micropores after removing the uppermost skin, forming micro/nanotextured surfaces and giving improvements in superhydrophobicity. Due to the elastomeric nature of SBR and EVA, the superhydrophobicity of the monoliths can be maintained even while the material is mechanically impacted or compressed, and wearing helps improvement or recovery of the superhydrophobicity because of the self-similarity of the cellular structure inside the monoliths. Additionally, the obtained superhydrophobic materials are resistant to acidic, alkali, and salt liquors as well as organic solvents and have easy healing capacity of superhydrophobicity with a simple sanding treatment when destroyed by exposure to oxygen plasma.

Sandpaper

Microscale chemistry

Ethylene-vinyl acetate

10.1021/acsomega.9b02535

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Superhydrophobic thermoplastic polyurethane/SiO2 sponge with dual-layer porous structure for summer radiative cooling and winter thermal insulation

Journal of Materials Science (2024)

Yuanyuan Qu Chao‐Hua Xue Bing‐Ying Liu Chao‐Qun Ma Xiao-Jing Guo

Radiative Cooling

Thermoplastic polyurethane

10.1007/s10853-024-10378-0

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Thermally Conductive, Superhydrophobic, and Flexible Composite Membrane of Polyurethane and Boron Nitride Nanosheets by Ultrasonic Assembly for Thermal Management

ACS Applied Polymer Materials (2023)

Zi-Hao Jiang Chao‐Hua Xue Xiao-Jing Guo Bing‐Ying Liu Huidi Wang

Thermal management is of significance for modern electronic products, and it remains challenging to keep the cooling performance of thermal management materials in multi-environment applications from being unaffected by external contamination. Herein, we constructed thermally conductive, superhydrophobic, and flexible composites using thermoplastic polyurethane electrospun membrane as a nano-fibrous substrate, hexagonal boron nitride nanosheets as a conducting filler, and polydimethylsiloxane/SiO2 nanoparticles for hydrophobization. The composite membrane demonstrated outstanding thermal management performance with an ultrahigh thermal conductivity (TC) of 7.193 W/m K. The membrane is flexible with durable TC even after 500 bending and stretching cycles and possesses superhydrophobicity with a water contact angle greater than 165° and a slide angle lower than 2.7°, which prevents the surface from being stained and protects its excellent TC for long-term applications, favoring thermal management of modern electronic products.

Thermoplastic polyurethane

Polydimethylsiloxane

10.1021/acsapm.2c01798

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A Superhydrophobic Dual-Mode Film for Energy-Free Radiative Cooling and Solar Heating

ACS Omega (2022)

Jiang-He Wang Chao‐Hua Xue Bing‐Ying Liu Xiao-Jing Guo Li-Cui Hu

Traditional electric cooling in summer and coal heating in winter consume a huge amount of energy and lead to a greenhouse effect. Herein, we developed an energy-free dual-mode superhydrophobic film, which consists of a white side with porous coating of styrene-ethylene-butylene-styrene/SiO2 for radiative cooling and a black side with nanocomposite coating of carbon nanotubes/polydimethylsiloxane for solar heating. In the cooling mode with the white side, the film achieved a high sunlight reflection of 94% and a strong long-wave infrared emission of 92% in the range of 8-13 μm to contribute to a temperature drop of ∼11 °C. In the heating mode with the black side, the film achieved a high solar absorption of 98% to induce heating to raise the air temperature beneath by ΔT of ∼35.6 °C. Importantly, both sides of the film are superhydrophobic with a contact angle over 165° and a sliding angle near 0°, showing typical self-cleaning effects, which defend the surfaces from outdoor contamination, thus conducive to long-term cooling and heating. This dual-mode film shows great potential in outdoor applications as coverings for both cooling in hot summer and heating in winter without an energy input.

Radiative Cooling

Mode (computer interface)

Dual mode

10.1021/acsomega.2c01947

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Fabrication of superhydrophobic coatings with edible materials for super-repelling non-Newtonian liquid foods

Chemical Engineering Journal (2019)

Bing‐Ying Liu Chao‐Hua Xue Qiufeng An Shun-Tian Jia Miaomiao Xu

10.1016/j.cej.2019.03.222

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Citations (82)