Einleitung: Das adenoid-zystische Ca (ACC) der Mamma ist mit einer Inzidenz von 0,1% aller Mamma-Ca sehr selten. Aufgrund Eigenschaften sind bei der Diagnostik u. Behandlung des ACC der Mamma einige Besonderheiten zu berücksichtigen. Es wird über eine 31-jährige Patientin mit einem ACC der re. Mamma berichtet.
The development of machine tools integrating multiple production technologies is challenging. To minimize the effort for implementation, a systematic conceptual design for hybrid machine tools is initiated already in early phases of product development. Reference product architectures are addressed. The main emphasis is on technology and system integration. A technological similarity assessment forms the basis to assure potential for synergies. The reference architecture introduced is validated by a Multi-Technology-Platform combining a milling spindle and two laser processing units.
Our modern society is increasingly depending on information and communication systems. This demands a high level of security and robustness on the implementations of network protocols. This paper presents a model-guided approach to discover security vulnerabilities of network protocol implementations. Our approach, resulted in security tool "Styx", introduces mutation analysis and model checking into fuzz testing and provides a synthesized protocol security testing. And it not only can perform syntax testing on the input data validation component of protocol implementations, but also is able to model the behaviors of a protocol and automatically generate test traces for the verification of its internal implemented functions. To proof the concept, experiments with the open source implementation of IKE/ISAKMP have also been provided. The results show that Styx can effectively be used to discover security vulnerabilities from network protocol implementations.
Einleitung: Insulinresistenz (IR) wurde bei Patienten mit chronischer Hepatitis C (HCV) nachgewiesen. Die Assoziation mit speziellen Genotypen ist noch umstritten. Es wurde beobachtet, dass IR & Präsenz des metabolischen Syndroms negativen Einfluss auf die antivirale Therapie haben können.
The coordinated use of surface- and ground-water over time and space as two components of a single irrigation system is of outmost importance in many rural areas of the world, in order to assure crop production sustainability, to restore ongoing and to prevent future issues related to freshwater quality and quantity mismanagement/deterioration. New technological solutions, such as GIS-integrated simulation models, may provide reliable tools in order to evaluate impacts in space and time and to properly manage conjunctive use of surface water and groundwater and water-constrained agricultural production. After presenting the common open source simulation programs for dealing with conjunctive use, we discuss and present the integration of the Farm Process (FMP; embedded in the USGS's MODFLOW One-Water Hydrologic Model) coupled to a Crop Growth Module (CGM) within the open source and public domain QGIS-integrated FREEWAT platform. Using FMP in FREEWAT gains the benefit of the spatial environment and data management tools of a GIS solution, and to perform proper analysis of dynamically integrated terms of the hydrological cycle, to effectively balance crop water demand and supply from different sources of water. A simple hypothetic, yet realistic, application of the proposed approach with FMP and CGM is presented, simulating the yield of irrigated sunflower at harvest in a Mediterranean area. Results provide an insight on the potential exploitation of the developed solution, including, but not limited, to: quantitative temporal analysis of irrigation water sources, detailed analysis of evaporation and transpiration terms (from irrigation, groundwater or rainfall). The coupling of FMP with CGM to estimate crop yield at harvest provides further management tools when dealing with crop productivity. In the simulated case study, the analysis of the water balance terms allowed identifying the relevance of the groundwater contribution to ETc-act, highlighting the role of natural root uptake. The proposed solution is thought to be deployed by water authorities, large farms and public/private companies managing irrigation areas. The use of these tools calls for dedicated capacity building to boost digitalization in the agricultural water sector in order to achieve data-based agricultural water management.
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