Propofol was administered intravenously using a first‐order, three‐compartment, computer‐controlled infusion pump (CCIP) based on the Ohmeda 9000 syringe pump. The CCIP system produced a target‐controlled infusion (TCI) based on the estimated blood concentration (EBC). Twenty‐five patients undergoing ambulatory surgery completed the study. The induction EBC was 4.72 ± 0.28 μg/ml, and was achieved rapidly with minimal hemodynamic changes. The emergence EBC was 1.55 ± 0.21 μg/ml, and the discharge EBC was 1.06 ± 0.22 μg/ml. The EBC, together with clinical signs, allowed for predictable inductance and emergence from anesthesia using propofol.
The authors examined residents' clinical performances in five anesthesiology departments in U.S. teaching hospitals. The data were organized by daily use of the Clinical Anesthesia System of Evaluation, which categorizes and quantifies the narrative comments of faculty. The study was designed to identify predictor categories (particular performance characteristics of residents) for the residents' overall performances and their scores in handling critical incidents (those incidents that could or would have caused significant morbidity or mortality had faculty not intervened). More than 9,000 comments made by 163 faculty about 45 residents were analyzed. Residents' noncognitive skills that were predictors of overall performance were Conscientiousness, Management, Confidence, Critical Incidents, and Knowledge. Conscientiousness and Composure predicted two-thirds of the variability in critical incidents' scores. Path analysis verified causal relationships between the hypothesized predictors and critical incidents. For the residents studied, inadequate noncognitive performance in some areas was a powerful (p less than .0005) predictor of overall clinical performance and was related to the occurrence of critical incidents.