Luca Lo Nigro

Policlinico Universitario di Catania

Author Statistics

Papers

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i-10 index

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Author Order

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Co-Authors

Giuseppe Basso

University of Padua

Andrea Biondi

University of Milano-Bicocca

Franco Locatelli

Università Cattolica del Sacro Cuore

Andrea Di Cataldo

University of Catania

Giovanni Cazzaniga

University of Milano-Bicocca

Valentino Conter

Azienda Ospedaliera San Gerardo

Carmelo Rizzari

University of Milano-Bicocca

Maria Grazia Valsecchi

University of Milano-Bicocca

Nicola Santoro

University of Bari Aldo Moro

Andrea Pession

Policlinico S.Orsola-Malpighi

Cooperative Institutions

Istituti di Ricovero e Cura a Carattere Scientifico

163

University of Catania

152

University of Padua

104

Leukemia Research Foundation

New York Blood Center

University of Milano-Bicocca

Boston Children's Hospital

Policlinico Universitario di Catania

Azienda Ospedaliera San Gerardo

Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele

Author Statistics

Papers

Citation

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Research Field

Ph-like and IKZF1plus Features in Children with Down Syndrome and B Cell Precursor Acute Lymphoblastic Leukemia

Blood (2022)

Chiara Palmi Silvia Bresolin Stefanie V. Junk Grazia Fazio Daniela Silvestri

Minimal Residual Disease

Acute lymphocytic leukemia

Cumulative incidence

Chemotherapy regimen

10.1182/blood-2022-169131

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Citations (0)

Complex MLL rearrangements in t(4;11) leukemia patients with absent AF4 · MLL fusion allele

Leukemia (2007)

Eric Kowarz Thomas Burmeister Luca Lo Nigro Mieke Jansen Éric Delabesse

Haploinsufficiency

Allelic exclusion

10.1038/sj.leu.2404686

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Citations (43)

Comparative analysis of bone marrow response kinetics in disseminated Burkitt’s lymphoma and B-cell acute leukemias.

Pediatric Blood & Cancer (2006)

Lara Mussolin Marta Pillon A. Lippi Matilde Piglione A. Lombardi

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Citations (0)

Pleuro-pulmonary ultrasound in the diagnosis and follow-up of lung infections in children with cancer: a pilot sudy

Authorea (Authorea) (2021)

Mariaclaudia Meli Milena La Spina Gian Luca Trobia Luca Lo Nigro Giovanna Russo

Febrile neutropenia and lung infections are common and potential fatal complications of pediatric cancer patients during chemotherapy. Lung ultrasound (LUS) has a good accurancy in the diagnosis of pneumonia in childhood. To our knowledge there are no studies concerning its utilization in the diagnosis and follow-up of pulmonary infection in children with cancer. The goal of this pilot study is to determine the accuracy of lung ultrasonography for the diagnosis and follow up of pneumonia in children and adolescents with cancer during fever. This is a prospective observational case-control monocentric study conducted in the Pediatric Hematology and Oncology Department of University Hospital of Catania in patients aged<18 years with cancer, with or without fever. Attending Physician used ultrasonography to diagnose pneumonia in children with cancer during fever. Non infected cancer patients were also tested with LUS to evaluate its accuracy. When performed, the results of chest X-ray and chest CT scan were compared with LUS results. Thirty-eight patients were studied. All underwent LUS, 16 underwent CXR, 3 chest CT. Statistical analysis showed LUS specificity of 95%, and sensitivity of 100%; CXR, instead showed a specificity of 80% and a sensitivity of 50%. The positive predictive value of LUS was 90% while that of CXR was 50%. The negative predictive value of LUS was 100% while that of CXR was 80%.This study shows for the first time that LUS allows physicians to diagnose pneumonia in children and young adults with cancer, with high specificity and sensitivity.

Lung Ultrasound

10.22541/au.162281697.79576084/v1

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Citations (0)

Final Results of the AIEOP (Associazione Italiana Ematologia/Oncologia Pediatrica) AML 2013 Prospective Randomized Trial in Childhood Acute Myeloid Leukemia (AML)

Blood (2023)

Franco Locatelli Barbara Buldini Martina Pigazzi Carmelo Rizzari Rosanna Cuccurullo

Minimal Residual Disease

Induction chemotherapy

Chemotherapy regimen

10.1182/blood-2023-188682

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Citations (0)

ASSOCIATION OF CYTOGENETIC ABNORMALITIES WITH DETECTION OF BCR-ABL FUSION TRANSCRIPTS IN CHILDREN WITH T-LINEAGE LYMPHOPROLIFERATIVE DISEASES

Luca Lo Nigro Laura Sainati Elena Mirabile Marina Lanciotti Amelia Poli

Lineage (genetic)

Lymphoproliferative Disorders

ABL

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Citations (0)

Unique BHLHB3 overexpression in pediatric acute myeloid leukemia with t(6;11)(q27;q23)

Leukemia (2014)

Eva A. Coenen C. Michel Zwaan Jan Starý André Baruchel Válerie de Haas

Hematology

10.1038/leu.2014.82

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Citations (4)

Risk of Seizures in Children Receiving Busulphan-Containing Regimens for Stem Cell Transplantation

Biology of Blood and Marrow Transplantation (2013)

Desirée Caselli Anna Rosati Maura Faraci Marta Podda Mimmo Ripaldi

Busulphan (BU) is associated with neurotoxicity and risk of seizures. Hence, seizure prophylaxis is routinely utilized during BU administration for stem cell transplantation (SCT). We collected data on the incidence of seizures among children undergoing SCT in Italy. Fourteen pediatric transplantation centers agreed to report unselected data on children receiving BU as part of the conditioning regimen for SCT between 2005 and 2012. Data on 954 pediatric transplantation procedures were collected; of them, 66% of the patients received BU orally, and the remaining 34%, i.v. All the patients received prophylaxis of seizures, according to local protocols, consisting of different schedules and drugs. A total of 13 patients (1.3%) developed seizures; of them, 3 had a history of epilepsy (or other seizure-related pre-existing condition); 3 had documented brain lesions potentially causing seizures per se; 1 had febrile seizures, 1 severe hypo-osmolality. In the remaining 5 patients, seizures were considered not explained and, thus, potentially related to BU administration. The incidence of seizures in children receiving BU-containing regimen was very low (1.3%); furthermore, most of them had at least 1-either pre-existing or concurrent-associated risk factor for seizures.

Regimen

Cumulative incidence

10.1016/j.bbmt.2013.10.028

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Citations (37)

TEL/AML1 Rearrangement Is Rare in Children with Acute Lymphoblastic Leukemia (ALL) and Down Syndrome (DS). Presenting Features and Treatment Outcome in the Experience of the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP).

Blood (2007)

Maurizio Aricò Ottavio Ziino Maria Grazia Valsecchi Giovanni Cazzaniga Carmelo Rizzari

Immunophenotyping

Acute lymphocytic leukemia

10.1182/blood.v110.11.848.848

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