Edita Vaičiūnaite

Vilnius University

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Sigitas Tumkevičius

Vilnius University

Stéphane Menuel

Université d'Artois

ÉM

Éric Monflier

Centre National de la Recherche Scientifique

Jolanta Rousseau

Université d'Artois

Cyril Rousseau

Unité de catalyse et de chimie du solide de Lille

Jelena Dodonova

Vilnius University

Virginija Jakubkienė

Vilnius University

Kamile Kriukaite

Vilnius University

J. Didzgalvis

Vilnius University

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Université d'Artois

Vilnius University

Unité de catalyse et de chimie du solide de Lille

Centre National de la Recherche Scientifique

École Centrale de Lille

Université de Lille

Catalyse

École Nationale Supérieure de Chimie de Lille

Centre de Géosciences

Université Lille Nord de France

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Access to Pyrrole Derivatives in Water with the Assistance of Methylated Cyclodextrins

European Journal of Organic Chemistry (2014)

Stéphane Menuel Jolanta Rousseau Cyril Rousseau Edita Vaičiūnaite Jelena Dodonova

Abstract A new and efficient catalytic protocol with which to synthesize N ‐substituted pyrrole derivatives from amines and 1,4‐diketones by Paal–Knorr condensation in aqueous medium has been developed by using partially methylated β‐cyclodextrins (RAME‐β‐CD). The modified cyclodextrins were used as mass transfer agents without catalyst for reactive ketones and with nitrophenol as catalyst for more hindered ketones.

Pyrrole

Aqueous medium

10.1002/ejoc.201402327

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Citations (18)

Efficient synthesis of novel 6-substituted 2-(4-aryl-1,2,3-triazol-1-yl)pyrimidines and 7-deazapurines

Synthetic Communications (2018)

Virginija Jakubkienė Edita Vaičiūnaite Kamile Kriukaite J. Didzgalvis Sigitas Tumkevičius

A simple and efficient synthesis of 6-substituted 2-(4-aryl-1,2,3-triazol-1-yl)pyrimidines and 7-deazapurines from readily available 6-chloro-2-methylthiopyrimidine and 6-chloro-2-methylthio-7-deazapurine derivatives is described. The synthetic strategy is based on sequential reactions: substitution of 6-chlorine group with amines or (2-pyridyl)tributylstannane, oxidation of the obtained 6-substituted 2-methylthiopyrimidines, and 7-deazapurines to the corresponding 2-methylsulfonyl derivatives, their conversion to 2-azido derivatives and Cu(I)-catalyzed azide − alkyne cycloaddition reaction with arylethynes.

Alkyne

10.1080/00397911.2018.1474229

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Citations (3)

ChemInform Abstract: Access to Pyrrole Derivatives in Water with the Assistance of Methylated Cyclodextrins.

ChemInform (2015)

Stéphane Menuel Jolanta Rousseau Cyril Rousseau Edita Vaičiūnaite Jelena Dodonova

Pyrrole

10.1002/chin.201508171

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