Leila Zeiad Gad

Cairo University

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Rabab Mohamed Abdelhay

Zagazig University

Wedad Z. Mostafa

Tanta University

Khadiga S. Sayed

Cairo University

Nahla Maher Mahran

Cairo University

Solwan Ibrahim El-Samanoudy

Cairo University

Manar Saeed Ali

Haidy Atef Afifi

Cairo University

Rania Abdel Hay

Cairo University

Cooperative Institutions

Cairo University

Advanced Dermatology

Zagazig University

Tanta University

King Faisal University

Ain Shams University

King's College London

Foundation for International Environmental Law and Development

National Research Centre

Ninewells Hospital

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Trichoscopic Diagnosis of Structural Hair Defects in a Clinical Setting: A Cross-Sectional Analytical Study

Skin Pharmacology and Physiology (2022)

Rania Abdel Hay Khadiga S. Sayed Wedad Z. Mostafa Haidy Atef Afifi Leila Zeiad Gad

Trichoscopy is a simple, noninvasive procedure practiced in the diagnosis of a multitude of scalp and hair disorders. Hair shaft abnormalities usually represent a diagnostic challenge to dermatologists.The aim of the study was to determine the practicality, versatility, and value of using the handheld dermoscope in the assessment of hair shaft abnormalities and the diagnosis of different hair/scalp disorders.Eight hundred and seven patients of both sexes, aged from 1 to 76 years, with complaints pertaining to scalp and hair, were the subjects of the study. All patients were examined by the handheld dermoscope, and 400 were additionally examined by the folliscope, digital dermoscope, or their hairs mounted for light microscopy.Based on trichoscopic findings, more than half the patients demonstrated thinned terminal hairs and a predominance of single-haired scalp pilosebaceous units (57% and 55.5%, respectively). Over a quarter of the patients showed hair diameter heterogeneity, upright regrowing hairs, and increased vellus hairs (37%, 31%, and 25%, respectively). Other trichoscopic findings included scalp scaling (19%), hair weathering (12%), thinned wavy hairs (10.5%), brush-like hair fractures (9%), exclamation mark hairs (9%), and longitudinal cleavage (trichoptilosis) (8%). The clinical diagnostic spectrum was topped by the following diagnoses in order of frequency: female pattern hair loss, telogen effluvium, traction alopecia, and trichotillomania. Trichodynia appeared to be significantly associated with numerous hair shaft abnormalities.Most hair shaft abnormalities can be reliably diagnosed with high accuracy using a handheld dermoscope in an office setting. Skillful knowledge of dermoscopy is an important aid in the diagnosis of hair and scalp disorders.

Cross-sectional study

10.1159/000526597

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Microneedling With Topical Insulin Versus Microneedling With Placebo in the Treatment of Postacne Atrophic Scars: A Randomized Control Trial

Dermatologic Surgery (2024)

Rabab Mohamed Abdelhay Manar Saeed Ali Leila Zeiad Gad Nahla Maher Mahran

BACKGROUND Among the treatment modalities for post-acne scars, microneedling is considered a safe and effective method. OBJECTIVE To compare the efficacy and safety of combined microneedling with topical insulin versus microneedling with placebo (topical saline) in treating atrophic acne scars. METHODS and MATERIALS Twenty-one patients with atrophic post-acne scars were randomized and treated in a split face manner with 4 sessions at 3-week intervals of microneedling using dermapen, followed by application of insulin on one side of the face and saline (placebo) on the other side. Evaluation of response was done before the sessions and after 1 month of the last session using the Global Scarring Grading System of Goodman & Baron and Lipper & Perez scores, Patient reported acne scar improvement using a 4-point scale, patient satisfaction, and the facial acne scar quality of life tools. RESULTS Both therapeutic modalities yielded a statistically significant improvement of atrophic acne scars. By comparing both modalities, there was no statistical significance regarding clinical improvement and side effects. CONCLUSION Using topical insulin combined with microneedling may have a value in improving atrophic acne scars, suggesting further evaluation using different delivery systems, insulin formulations, and assessment modalities.

Acne scars

10.1097/dss.0000000000004462

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