Р.И. Ишметова

Research Field

Dissociation constant

Base (topology)

10.1134/s1070428009070197

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Citations (15)

HETARYL DISPLACEMENT IN 3,6-DISUBSTITUTED 1,2,4,5-TETRAZINES WITH ANHYDRO BASES OF N-METHYLQUINALDINIUMS

Heterocyclic Communications (2006)

Gennady L. Rusinov Р.И. Ишметова I.N. Ganebnykh О. Н. Чупахин

3,6-Bis(4-R-3,5-dimethylpyrazol-1 -yl)-s-tetrazine, 3,6-bis(imidazol-1 -yl)-s-tetrazine, 3,6bis(benzotriazol-l-yl)-s-tetrazine,3,6-bis(4-methylimidazol-l-yl)-s-tetrazine react with anhydro bases of 1-methylquinaldium and 1,6-dimethylquinaldium to form products of C-nucleophilic substitution of azolyl fragment or Carboni-Lindsey reaction followed by subsequent pyridine ring cleavage in the quinoline moiety.

10.1515/hc.2006.12.2.99

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Citations (11)

Synthesis of 1,2,4,5-tetrazines, symmetrically and unsymmetrically 3,6-disubstituted by N-nucleophiles

Russian Journal of Organic Chemistry (2006)

Gennady L. Rusinov Н. И. Латош I. I. Ganebnykh Р.И. Ишметова N.K. Ignatenko

Moiety

Substitution reaction

10.1134/s1070428006050198

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Citations (22)

CCDC 795393: Experimental Crystal Structure Determination

The Cambridge Structural Database (2012)

E.S. Salmina G.L. Rusinov Павел А. Слепухин Р.И. Ишметова S.G. Tolshchina

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccvpnv0

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Citations (0)

Synthesis and Antibacterial and Antifungal Activity of 3-(Azol-1-Yl)-6-R-1,2,4,5-Tetrazines

Pharmaceutical Chemistry Journal (2020)

Р.И. Ишметова Н. А. Герасимова Н. П. Евстигнеева I.A. Belyaninova N.K. Ignatenko

10.1007/s11094-020-02097-y

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Citations (4)

Synthesis of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines and investigation of their fungistatic activity

Beilstein Journal of Organic Chemistry (2022)

А.V. Korotina S.G. Tolshchina Р.И. Ишметова Н. П. Евстигнеева Н. А. Герасимова

A series of novel [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines has been synthesized through oxidation reaction of the corresponding 3,6-disubstituted 1,2,4,5-tetrazines bearing amidine fragments. It is shown that the heterocyclic systems obtained can be modified easily at C(3) position in the reactions with aliphatic alcohols and amines. Also, the reactivity of [1,2,4]triazolo[1,5-b][1,2,4,5]tetrazines towards CH-active compounds has been studied. The obtained triazolo[1,5-b]annulated 1,2,4,5-tetrazines proved to be active in micromolar concentrations in vitro against filamentous anthropophilic and zooanthropophilic dermatophyte fungi (Trichophyton, Microsporum and Epidermofiton), which cause skin and its appendages (hair, nails) diseases.

Reactivity

Dermatophyte

Amidine

10.3762/bjoc.18.29

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Citations (3)

ChemInform Abstract: Synthesis of Some 5‐Aryl(hetaryl)tetrazoles Using the Ultrasound Techniques.

ChemInform (1995)

Г. Л. Русинов Р.И. Ишметова V. G. Kitaeva Dmitry G. Beresnev

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199528149

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Citations (0)

Synthesis and reactions of 7-phenylimidazo[1,2-b][1,2,4,5]tetrazines with nucleophiles

Russian Chemical Bulletin (2018)

I.N. Ganebnykh Р.И. Ишметова S.G. Tolshchina А.V. Korotina D.S. Filatov

10.1007/s11172-018-2281-6

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Citations (5)

CCDC 807609: Experimental Crystal Structure Determination

The Cambridge Structural Database (2011)

I.N. Ganebnykh S.G. Tolshchina Р.И. Ишметова N.K. Ignatenko Павел А. Слепухин