E. Ortega García

Instituto de Investigación Marqués de Valdecilla

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A. Vega Bolívar

Marqués de Valdecilla University Hospital

P. Merino Rasillo

Instituto de Investigación Marqués de Valdecilla

P. Bartolomé

Hospital Del Mar

Pedro Muñoz

Servicio Cántabro de Salud

Pilar Alonso-Bartolomé

Marqués de Valdecilla University Hospital

M. Sánchez Movellán

Consejería de Educación de la Junta de Castilla y León

Sonia Sánchez Gómez

Marqués de Valdecilla University Hospital

Sheila Sánchez Gómez

Instituto de Investigación Marqués de Valdecilla

F. Garijo Ayensa

Marqués de Valdecilla University Hospital

E. Herrera Romero

Instituto de Investigación Marqués de Valdecilla

Cooperative Institutions

Marqués de Valdecilla University Hospital

Instituto de Investigación Marqués de Valdecilla

Universidad de Cantabria

Hospital Sierrallana

Osakidetza

Universidad de Navarra

Research Institute of Radiology

University of Pennsylvania

Autonomous University of San Luis Potosí

Universidad de Tamazunchale

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Carcinoma de intervalo en un programa de cribado de cáncer de mama (2007-2018). Características y pronóstico

Radiología (2023)

P. Bartolomé P. Merino Rasillo Sheila Sánchez Gómez E. Herrera Romero E. Ortega García

10.1016/j.rx.2023.03.005

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Ultrasound-guided core needle biopsy of non-palpable breast lesions: a prospective analysis in 204 cases

Acta Radiologica (2005)

A. Vega Bolívar Pilar Alonso-Bartolomé E. Ortega García F. Garijo Ayensa

Purpose: To assess the diagnostic value of ultrasound (US)-guided 14 G core needle breast biopsy in non-palpable suspicious breast lesions. Material and Methods: From August 1997 to April 2001, 198 patients with 204 suspicious non-palpable breast lesions underwent US-guided large core needle biopsy. Biopsies were performed with a free-hand technique using US equipment with a 7.5 MHz linear-array transducer; a minimum of three cores were obtained from each lesion. Pathological findings in US-guided core biopsy were correlated to findings in subsequent surgery or long-term (more than 2 years) imaging follow-up. Results: Among the 204 non-palpable breast lesions for which histopathological findings were obtained by US-guided core biopsy, 118 were malignant (114 carcinoma, 2 metastasis, 1 lymphoma, and 1 malignant phyllodes tumor) and 86 were benign (4 carcinoma and 82 benign lesions confirmed at surgery or after at least 2 years of follow-up). Sensitivity, specificity, positive predictive value, and negative predictive value for diagnosis of malignancy in our series were 97%, 100%, 100%, and 95%, respectively. Diagnostic yield with 1, 2, 3, and 4 specimens per lesion was 73.5%, 88%, 94%, and 97.5%, respectively. Conclusion: US-guided core needle biopsy is a sensitive percutaneous biopsy method for diagnosing non-palpable breast lesions. To achieve a high diagnostic yield, a minimum number of three cores per lesion is advisable.

Breast carcinoma

10.1080/02841850500225740

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Citations (51)

PROGRAMA DE DETECCIÓN PRECOZ DE CÁNCER DE MAMA.: INDICADORES DE CALIDAD.

Seram (2018)

Pilar Alonso Bartolomé Alexandra De Diego Díez Eduardo Romero P. Merino Rasillo E. Ortega García

OBJETIVOS: • El cribado sistematico mediante mamografia, ofrece la posibilidad de reducir la mortalidad por cancer de mama y aminorar los efectos adversos del tratamiento.• Para conseguir los objetivos previstos es necesario que los programas de cribado cumplan unos criterios de calidad establecidos. MATERIAL Y METODOS - Se estudia una vuelta completa del Programa de cribado de cancer de mama (2013 2014) en Cantabria.- Cribado con mamografia en mujeres de edad entre 50 y 69 anos.- Analizaremos los indicadores de calidad: porcentaje de participacion, tasa de deteccion de cancer de mama, porcentaje de Carcinoma ductal in situ (CDIS) y canceres invasivos de tamano igual o inferior a 1 cm, porcentaje de canceres invasivos sin afectacion ganglionar y tasa de canceres de intervalo.

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Interval carcinomas in a breast cancer screening program (2007–2018): Characteristics and prognosis

Radiología (English Edition) (2024)

P. Bartolomé P. Merino Rasillo Sheila Sánchez Gómez E. Herrera Romero E. Ortega García

10.1016/j.rxeng.2023.03.009

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Is excisional biopsy warranted after a diagnosis of flat epitelial atypia (FEA) at vacuum-assisted biopsy?

P. Merino Rasillo P. Bartolomé E. Ortega García S. Mayor Gómez Eduardo Torres Díez

Poster: ECR 2015 / C-0632 / Is excisional biopsy warranted after a diagnosis of flat epitelial atypia (FEA) at vacuum-assisted biopsy? by: P. Merino Rasillo , P. Alonso Bartolome, E. Ortega Garcia, S. M. Sanchez Gomez, E. Torres Diez, A. Vega Bolivar; Santander/ES

Atypia

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Intraductal placement of a kopans spring-hookwire guide to localize nonpalpable breast lesions detected by galactography

Acta Radiologica (1997)

A. Vega Bolívar R. M. Landeras Alvaro E. Ortega García

Purpose: to evaluate a new procedure for locating intraductal breast lesions detected by galactography, using the technique of intraductal placement of a Kopans spring-hookwire guide. Material and Methods: A catheter (0.7 mm) with a Kopans hookwire guide inside it was placed in 34 patients in whom an intraductal growth had been detected by galactography. the catheter was introduced through the discharging duct, with one hand holding the catheter and the other hand gently pushing the Kopans guide until it was anchored in the duct. the correct position of the guide was confirmed with new galactograms. Results: A precise excision of the lesion was satisfactorily executed in 29 of 34 patients (85%) who underwent this procedure. in 5 patients the method was unsuccessful because the Kopans guide was dislodged. Conclusion: This method is effective in removing intraductal lesions because it ensures a precise ductal excision and enables the pathologist to find the lesion more easily.

Nipple discharge

Intraductal papilloma

10.1080/02841859709172056

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Computer-aided detection system applied to full-field digital mammograms

Acta Radiologica (2010)

A. Vega Bolívar Sonia Sánchez Gómez Paula Merino Pilar Alonso-Bartolomé E. Ortega García

although mammography remains the mainstay for breast cancer screening, it is an imperfect examination with a sensitivity of 75-92% for breast cancer. Computer-aided detection (CAD) has been developed to improve mammographic detection of breast cancer.to retrospectively estimate CAD sensitivity and false-positive rate with full-field digital mammograms (FFDMs).CAD was used to evaluate 151 cases of ductal carcinoma in situ (DCIS) (n=48) and invasive breast cancer (n=103) detected with FFDM. Retrospectively, CAD sensitivity was estimated based on breast density, mammographic presentation, histopathology type, and lesion size. CAD false-positive rate was estimated with screening FFDMs from 200 women.CAD detected 93% (141/151) of cancer cases: 97% (28/29) in fatty breasts, 94% (81/86) in breasts containing scattered fibroglandular densities, 90% (28/31) in heterogeneously dense breasts, and 80% (4/5) in extremely dense breasts. CAD detected 98% (54/55) of cancers manifesting as calcifications, 89% (74/83) as masses, and 100% (13/13) as mixed masses and calcifications. CAD detected 92% (73/79) of invasive ductal carcinomas, 89% (8/9) of invasive lobular carcinomas, 93% (14/15) of other invasive carcinomas, and 96% (46/48) of DCIS. CAD sensitivity for cancers 1-10 mm was 87% (47/54); 11-20 mm, 99% (70/71); 21-30 mm, 86% (12/14); and larger than 30 mm, 100% (12/12). The CAD false-positive rate was 2.5 marks per case.CAD with FFDM showed a high sensitivity in identifying cancers manifesting as calcifications or masses. CAD sensitivity was maintained in small lesions (1-20 mm) and invasive lobular carcinomas, which have lower mammographic sensitivity.

Digital Mammography

Histopathology

10.3109/02841851.2010.520024

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Citations (15)

Stereotaxic core needle aspiration biopsy with multiple passes in nonpalpable breast lesions

Acta Radiologica (1998)

A. Vega Bolívar E. Ortega García F. Garijo Ayensa

Objective: To compare the grade of histologic agreement between stereotaxic core needle aspiration biopsy (SCNAB) with multiple passes, and surgical excision. Methods: A total of 180 patients with 182 nonpalpable breast lesions underwent SCNAB with multiple passes in an upright add-on stereotaxic device using a manual 1.8-mm needle (15 G). In this group, 125 patients underwent subsequent surgical excision. Results: A SCNAB result indicative of malignancy (invasive or noninvasive carcinoma) was obtained in 68 (87%) of the 78 breast carcinomas (14 noninvasive and 64 invasive) and definitive surgical therapy with a one-stage procedure was performed. Complete or partial agreement between core biopsy and surgery was observed in 19 (86%) of 22 invasive or noninvasive carcinomas discovered by microcalcifications, 40 (97.5%) of 41 invasive carcinomas discovered by a mass, and 9 (60%) of 15 invasive or noninvasive carcinomas discovered by architectural distortion. Six (33%) of the 18 patients whose core biopsies showed noninvasive carcinoma had an invasive or microinvasive component at subsequent surgery. Atypical hyperplasia or benign core biopsy was observed in 6 (8%) and 4 (5%) breast carcinomas respectively. Conclusion: SCNAB with multiple passes is a reliable method for identifying nonpalpable lesions in patients with noninvasive or invasive carcinomas discovered by respectively microcalcifications or mass.

Core biopsy

10.1080/02841859809172451

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Uso del Cuestionario de Capacidades y Dificultades (SDQ) como instrumento de cribado de trastornos psiquiátricos en la consulta de pediatría de Atención Primaria

D. Mata Zubillaga Suárez Rodríguez C. Torres Hinojal A. Carro Serrano E. Ortega García

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Pathological findings of suspicious axilary lymph nodes in patients with normal screening mammograms

E. Lopez Uzquiza A. Iturralde-Garriz A. De Diego Diez P. Bartolomé E. Ortega García

Poster: ECR 2015 / C-1031 / Pathological findings of suspicious axilary lymph nodes in patients with normal screening mammograms by: E. Lopez Uzquiza 1, A. Iturralde-Garriz2, A. De Diego Diez2, P. Alonso Bartolome1, E. Ortega Garcia1, P. Merino Rasillo1; 1Suances/ES, 2Santander/ES

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