Céline Fournier

Idorsia (Switzerland)

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Laurent Sandrin

Ipsen (France)

Véronique Miette

École Nationale Vétérinaire d'Alfort

Stephen A. Harrison

GKN (United States)

Philip N. Newsome

King's College Hospital

Quentin M. Anstee

NIHR Newcastle Biomedical Research Centre

Jérôme Boursier

Centre Hospitalier Universitaire d'Angers

Jörn M. Schattenberg

University Medical Center of the Johannes Gutenberg University Mainz

Victor de Lédinghen

Hôpital Cardiologique du Haut-Lévêque

Pierre Bédossa

Université Paris Cité

Jeremy Cobbold

John Radcliffe Hospital

Cooperative Institutions

Inserm

Screen

Clinical Research Consortium

Sorbonne Université

Centre National de la Recherche Scientifique

Assistance Publique – Hôpitaux de Paris

Université Paris Cité

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

Universitat de Barcelona

Hospital Clínic de Barcelona

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P1C-2 Liver Stiffness Measurement Using Transient Elastography in Patients with Non-Alcoholic Fatty Liver (NAFLD) and Non-Alcoholic Steatohepatitis (NASH)

Proceedings/Proceedings - IEEE Ultrasonics Symposium (2007)

Véronique Miette Céline Fournier L. Adara Laurent Sandrin

Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of injury in many countries around the world. NAFLD covers a wide spectrum, ranging from simple steatosis, which is generally non progressive, to nonalcoholic steatohepatitis. There are no established noninvasive methods of evaluation for patients with NASH and until recently, liver biopsy was the unique method to quantify liver fibrosis. Liver stiffness measurement (LSM) has been proposed as non invasive tool to assess liver fibrosis in patients with hepatic chronic disease. This poster presents 3 clinical studies which demonstrate the usefulness of LSM to assess liver fibrosis in patients with histological features of NAFLD and which compared the efficiency of LSM and of two blood markers.

Transient elastography

Steatohepatitis

Steatosis

Chronic liver disease

10.1109/ultsym.2007.335

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Citations (3)

Comparison of optical, electrical, and centrifugation techniques for haematocrit monitoring of dialysed patients

Medical & Biological Engineering & Computing (1999)

Michel Y. Jaffrin Céline Fournier

Ultrafiltration (renal)

10.1007/bf02513326

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Citations (19)

Diagnostic accuracy of non-invasive tests for fibrotic NASH-An individual participant data meta-analysis

Journal of Hepatology (2022)

Ferenc E. Mózes Jenny Lee Yasaman Vali Emmanuel Selvaraj Arjun Jayaswal

10.1016/s0168-8278(22)01237-5

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Citations (0)

Comportement à l’exercice des patients atteints de protéinose alvéolaire

Revue des Maladies Respiratoires (2005)

Nathalie Bautin Céline Fournier Emilie Marie Stéphane Robin Rémi Nevière

10.1016/s0761-8425(05)85725-0

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Totally implantable venous access port systems and risk factors for complications: A one-year prospective study in a cancer centre

European Journal of Surgical Oncology (2011)

Fabrice Narducci Mehdi Jean-Laurent Luke Boulanger Sophie El Bedoui Y. Mallet

Venous access

Port (circuit theory)

10.1016/j.ejso.2011.06.016

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Citations (117)

Lanifibranor therapy reduces the FibroScan-aspartate aminotransferase (FAST) score associated with histological ‘NASH resolution and improvement of fibrosis’ and biomarker response

Journal of Hepatology (2022)

Michael P. Cooreman Manal F. Abdelmalek Martine Baudin Philippe Huot-Marchand Lucile Dzen

10.1016/s0168-8278(22)01762-7

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Citations (0)

Cas clinique n° 4

Revue des Maladies Respiratoires Actualités (2021)

Céline Fournier

10.1016/s1877-1203(21)00007-0

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Individual patient data meta-analysis of the diagnostic performance of single and sequentially combined non-invasive tests in detecting advanced fibrosis

Ferenc E. Mózes Jenny Lee Emmanuel Selvaraj Arjun Jayaswal Michael Trauner

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Transient Elastography: From Research to Noninvasive Assessment of Liver Fibrosis Using Fibroscan®

Laurent Sandrin M. Sasso Stéphane Audière Cécile Bastard Céline Fournier

This chapter presents the principles of transient elastography. It focuses on Fibroscan device and the clinical review of its applications to liver diseases. The chapter discusses the applications of transient elastography. Transient elastography yielded the development of an average stiffness measurement method referred as 1D transient elastography. The technique relies on a single element ultrasound transducer and a mechanical actuator. 1D transient elastography was successfully applied to in vivo measurement of liver stiffness. Several probes are being used with FibroScan depending on the patient morphology. Liver stiffness measurement has been shown to have utility beyond the assessment of liver fibrosis stage. Esophageal varices (EV) represent one of the most severe complications of cirrhosis. The performances of spleen stiffness measurement were assessed with a modified FibroScan in order to detect the presence of significant EV in cirrhotic patients.

Transient elastography

Hepatic fibrosis

Transient (computer programming)

10.1002/9781119021520.ch20

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GYN6 Apport de l’etude dynamique de la prise de contraste en IRM pour evaluer la reponse a l’irradiation des cancers inferieurs a 4 cm du col uterin

Journal de Radiologie (2004)

S. Taïeb L. Ceugnart B. Castelain Céline Fournier A. Chevalier

10.1016/s0221-0363(04)77544-7

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