Ali Timuçin Atayoğlu

Istanbul Medipol University

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i-10 index

Research Trends

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Co-Authors

Sibel Doğan

Istanbul Medipol University

Sibel Sílící

Erciyes University

Ayten Güner Atayoğlu

Istanbul Medipol University

Nİ

Neriman İnanç

Nuh Naci Yazgan University

OÖ

Onur Öztürk

Samsun University

İE

İsmaıl Evren

Bakırköy Dr.Sadi Konuk Eğitim ve Araştırma Hastanesi

İT

İlknur Topal

Istanbul Medipol University

Abdürrahim Koçyiğit

Bezmiâlem Vakıf Üniversitesi

Aslı Gizem Çapar

Nuh Naci Yazgan University

MÜ

Mustafa Ünal

State Hospital

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

University of Health Science

University of Health Sciences

Istanbul Medipol University

Erciyes University

Istanbul University

State Hospital

Ondokuz Mayıs University

Kayseri Eğitim ve Araştırma Hastanesi

Ankara University

Author Statistics

Papers

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Assessment of Association Between the Potential Immunomodulatory Activity and Drinking Olive Leaf Tea in the Coronavirus Disease-2019 Pandemic: An Observational Study

Journal of Integrative and Complementary Medicine (2022)

Abdürrahim Koçyiğit Eray Metin Güler Arzu İrban Bayram Kıran Ali Timuçin Atayoğlu

Objective: During the Coronavirus Disease-2019 (COVID-19) pandemic, in addition to the current measures, the healthy immune system plays an essential role and various natural agents have been recommended to boost innate immunity. The aim of this study was to investigate any association between the potential immunomodulatory activity and drinking olive leaf tea (OLT) in the COVID-19 pandemic. Design: The study was conducted among the workers in a tractor factory where OLT was served in routine. Drinking at least one cup of OLT per day for a minimum of 1 month was the inclusion criteria used in the study. The workers who had a history of vaccination and COVID-19 were excluded from the study, and lymphocyte subsets, interleukin (IL)-2, IFN-γ, COVID-19-specific IgM and IgG levels were analyzed in all the participants to determine the asymptomatic individuals among the participants and compare the immunological parameters. Results: The study was conducted among 336 workers, 183 of them were OLT drinkers and 153 were OLT nondrinkers. The results showed higher values of CD3-/CD16/56 (natural killer [NK]) cells, CD3+/CD16/56 (natural killer T [NKT]) cells, total NK (NK+NKT) cells, and serum IFN-γ, and IL-2 levels in OLT drinkers compared to the nondrinkers. Although all the OLT drinkers and nondrinkers included in the study reported no history of COVID-19, specific COVID-19 IgG levels were found positive in 60% of OLT drinkers and 38% OLT nondrinkers. Conclusions: Peripheral NK and NKT cell values and IL-2 and IFN-γ secretion levels were found higher in the OLT drinking group. There were positive correlations between the OLT drinking frequency and NK cell counts. Moreover, the number of individuals who had "asymptomatic" COVID-19 infection was higher in the OLT drinking group than in the nondrinking cohort. Clinical Trial Registration Number: The trial has been registered in the ClinicalTrials.gov database (CTR NCT05222347).

Pandemic

CD16

10.1089/jicm.2022.0554

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Holistic Approach In Stroke Patients: A Clinical Trial

Medical Science and Discovery (2023)

Abdulvahap Kaya Ali Timuçin Atayoğlu

Objective: This study aimed to explore the holistic relationship between personality types, coping attitudes, physical functioning, and cognitive levels in individuals diagnosed with stroke. Material and Methods: The research employed a single-group design and included 25 stroke patients. The participants, comprising 7 females and 12 males with a mean age of 54.211±8.979 years, underwent a comprehensive assessment. Physical function was assessed using the Berg Balance Scale and Timed Up and Go Tests, and cognitive levels were measured with the Montreal Cognitive Assessment Scale, coping strategies were evaluated through the COPE-R Coping Attitudes Evaluation Scale, and personality types were determined using the Enneagram Scale. Results: A significant correlation was identified between the Montreal Cognitive Assessment, Timed Up and Go, and Berg Balance Scales (p<0.05). However, no significant correlation was observed between COPE-R Coping Attitudes and Enneagram scales (p=0.503). Conclusion: This study underscores the interplay between cognitive and physical functioning in stroke survivors, highlighting the potential impact of cognitive levels on physical capabilities. Surprisingly, coping attitudes and personality types did not significantly influence cognitive or physical function.

Montreal Cognitive Assessment

Stroke

10.36472/msd.v10i10.1064

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Comparison of Medical Treatment and Acupuncture in Treatment of Psychogenic Erectile Dysfunction: a Prospective, Randomized, Placebo-Controlled Study

International Journal of Traditional and Complementary Medicine Research (2021)

İsmaıl Evren İlhan Öztekin Ali Timuçin Atayoğlu Noor Buccholz

Objective: Erectile dysfunction (ED) is the persistent inability to achieve or maintain an erection that is sufficient for satisfactory sexual performance. The aim of this study was to assess the impact of acupuncture in psychogenic ED patients, in comparison with the medical treatment. Material-Method: A total of 60 male patients, with psychogenic ED were randomized into 4 groups as electro-acupuncture only, electro-acupuncture and oral sildenafil 25 mg, a placebo sham acupuncture and oral sildenafil 50 mg only. The treatment lasted for six weeks in all groups, and patients were evaluated with the International Index of Erectile Function (IIEF-5 scores).Results: After the treatment, all groups except the placebo group showed a significant increase in IIEF-5 scores, without significant differences among them. Conclusion: Acupuncture can be used in the complementary treatment of psychogenic ED patients.

Psychogenic disease

10.53811/ijtcmr.985680

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İstanbul’daki aile hekimlerinin geleneksel ve tamamlayıcı tıp bakış açıları

Family practice and palliative care (2023)

Ali Timuçin Atayoğlu Mahmut Tokaç Sibel Doğan Abdullah Emre Güner Erdoğan KOCAYİĞİT

Introduction: The World Health Organization, within the scope of the Traditional Medicine Strategy for 2014-2023, recommends the development of integrated health policies, particularly in the area of primary healthcare. However, family physicians often report feeling insufficiently trained to effectively integrate these practices into patient care. This study aims to assess the views, understanding, and experiences of family physicians regarding the utilization of Traditional & Complementary Medicine (T&CM).Methods: The family physicians employed by the Istanbul Health Directorate Public Health Services were solicited to participate in an 18-question online survey to assess their level of education in T&CM methods, their views on integration of T&CM into family medicine, and the impact of these practices on patient care.Results: A total of 324 family physicians took part in the survey; 12.0% were specialists, 64.5% had worked in primary care for over 10 years, and 59.6% were in the age range of 31-50 years. Among the physicians, the majority (70.1%) reported a preference for integrating T&CM practices with conventional medicine (ConvM). The majority of the participants (71.6%) had no formal T&CM training, and 66.4% reported inquiring about T&CM in their patient consultations. Over half of the physicians (56.79%) believed that T&CM methods should be used in preventive medicine. The most widely recognized T&CM technique was cupping therapy (18.5%), which was also the most frequently recommended method by physicians.Conclusion: Most of the family physicians who participated in the study expressed a desire for integrative medicine, despite acknowledging limited formal education in this field. Offering physicians training in evidence-based complementary medicine therapies could provide them with additional non-invasive treatment options. However, patients' diffidence to inform their family physicians about T&CM practices they undergo may pose significant risks. As a result, incorporating education on integrative medicine into formal medical education and residency training may be necessary.Keywords: Family physician, complementary medicine, integrative medicine, traditional medicine

Scope of Practice

10.22391/fppc.1192917

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Transfer anxiety in critical care patients and their caregivers

Family practice and palliative care (2020)

Merve Bat Tonkuş Sibel Doğan Ali Timuçin Atayoğlu

Introduction: Both admission and discharge in the critical care units can cause anxiety in the patients and their family caregivers. Coordination and integration of primary and secondary healthcare is important for those individuals. The aim of the study was to investigate the transfer anxiety in patients and their caregivers due to being transferred from the intensive care unit (ICU).Methods: This is a descriptive study that was carried out through interviewing with the patients and their caregivers who were hospitalized in the ICU and then transferred out due to the improvement of their general condition. The data of the study were carried out by using a Questionnaire Form and the State-Trait Anxiety Inventory (STAI).Results: A total of 170 individuals (85 patients and 85 family caregivers) were involved in the study. The patient’s anxiety scores were higher than their caregivers and the difference was statistically significant (p<0.001). The patients and their caregivers’ mean anxiety scale scores after the transfer were higher in comparison with the mean scores before the transfer and the difference was statistically significant (p<0.001). Conclusions: Patients and their caregivers experience transfer anxiety due to being transferred from the ICU. Therefore, healthcare professionals are encouraged to make the necessary adjustments to prevent transfer anxiety. In this process, the involvement of primary healthcare professionals, in particular family physicians and nurses, who know them closely is crucial.

Interview

Family Caregivers

Health Professionals

10.22391/fppc.787056

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Burnout Syndrome in Urology Residents: A Multicenter Survey Study

Zenodo (CERN European Organization for Nuclear Research) (2022)

İsmaıl Evren Ubeyd Sungur Mithat Ekşi Taner Kargı Hakan Polat

Burnout Syndrome

10.5281/zenodo.7296628

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Quercus pyrenaica Honeydew Honey With High Phenolic Contents Cause DNA Damage, Apoptosis, and Cell Death Through Generation of Reactive Oxygen Species in Gastric Adenocarcinoma Cells

Integrative Cancer Therapies (2019)

Abdürrahim Koçyiğit Gökhan Aydoğdu Ezgi Balkan Vildan Betül Yenigün Eray Metin Güler

Many studies have shown that honey with high phenolic contents prevents cancer formation. Furthermore, recent studies have demonstrated that honey can be used for the treatment of cancer as well as cancer prevention. Antineoplastic effects of honey are often associated with their antioxidant phenolic contents. However, very few studies have dealt with the association of phenolic contents of honeys in terms of antiproliferative effects. The aim of this study was, therefore, to elucidate the cytotoxic, genotoxic, apoptotic, and reactive oxygen species (ROS) generating effects of honey samples on the basis of their phenolic and flavonoid contents. Fourteen different honey varieties were collected from various parts of Turkey, and their characteristics regarding total phenols, flavonoids, and antioxidant contents were determined to test their effects on gastric cancer cells (AGS). For convenience, 2 honey varieties were selected, namely, Ida Mountains Quercus pyrenaica honeydew honey (QPHH-IM) having the highest phenolic and antioxidant content and Canakkale multifloral honey (MFH-C) with the lowest phenolic and antioxidant content. Levels of 11 different phenolic compounds in QPHH-IM and MFH-C samples were determined by LC-MS/MS. AGS cells were incubated with different concentrations of QPHH-IM and MFH-C for 24 hours, then the cell viability, DNA damage, apoptosis, and generation of ROS were determined. We found that QPHH-IM had more cytotoxic, genotoxic, and apoptotic effects than that of MFH-C. We think that these effects are probably related to pro-oxidant activities due to the high phenolic contents present. Therefore, further research on high-phenolic honey may contribute to the future development of cancer therapeutics.

Honeydew

10.1177/1534735419876334

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Citations (22)

Is there a place for a holistic approach in surgical training?

Arab Journal of Urology (2013)

Ali Timuçin Atayoğlu Noor Buchholz Ayten Güner Atayoğlu Müjgan Çalışkan

Introduction:The holistic approach in medicine is a framework that considers and treats all aspects of a patient's needs, as it relates to their health. The goal of such an approach is to prevent illness, and to maximise the well-being of individuals and families. Holistic medicine is also referred to as integrative, which has been interpreted by some professionals as the combination of evidence-based medicine and complementary medicine.The problem:The speciality of Family Medicine (FM) is often referred to as General Practice (GP), a terminology which emphasises the holistic nature of that discipline. Furthermore, GP/FM professional bodies in some countries have incorporated the holistic and integrative approach into curricula and guidelines for doctors in training, which reflects its acceptance as a component of medical training. However, despite this validation, and despite research showing the effectiveness of such strategies in enhancing the outcomes of surgery, a holistic framework or integrative approach has not been equally integrated into speciality training for would-be surgeons.Conclusion:We argue that it would be advisable to include holistic approaches into surgical training and help surgeons to recognise their role in the continuum of care.

10.1016/j.aju.2013.06.005

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Citations (5)

Knowledge Level and Opinions of Secondary School Students About Traditional and Complementary Medicine

DergiPark (Istanbul University) (2021)

Onur Öztürk Mustafa Ünal Muhammet Ali Oruç Ali Timuçin Atayoğlu Mustafa Yasin Selçuk

Objective: The place of traditional and complementary medicine (TC of the approaches in T&CM, the highest level of awareness was about 'hypnosis' (67.7%). It was found out that information about T&CM approaches was mostly acquired from the media (32.0%). Of the student opinions about T&CM, 40.7% were positive. The percentage of students thinking that classical medicine and T&CM can be integrated and complement each other was 32.5% (n=149). Most of the students with a family member utilizing T&CM were wishing to work in the health sector in the future (32.1%) (p=0.02) and aiming to have a T&CM-related job more than other participants (32.7%) (p=0.001). Conclusion: The level of awareness about T&CM was found to be low among secondary school students. If health literacy education in schools is organized better, awareness of T&CM may grow.

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Analysis of post-migration traumatic events influence on immigrants and their personality traits

Central European Journal of Public Health (2023)

İlknur Aydın Avcı Mehmet Korkmaz Özge Öz Yıldırım Ayşe Çal Hakan Gülerce

This study aims to analyse the way immigrants and their personality traits get affected by traumatic events in the post-migration process.This descriptive study was conducted through Google Forms with the involvement of 2,509 immigrants. A descriptive questionnaire, the "IFOMA Post-Migration Post-Traumatic Effect Scale" and the "GADOT Personality Types Determination Scale" were used to collect the research data. Independent samples t-test, one-way ANOVA, and related sample Friedman's two-way analysis tests were used in data analysis.Immigrants were exposed to significant effects in all sub-dimensions of the Post-Migration Post-Traumatic Effect Scale. Experiencing post-traumatic stress was found to be significantly related to the research parameters, which, respectively, are gender, age, marital status, educational background, legal status, years of living in the current country, employment status, ethnicity, Turkish language proficiency, and post-migration psychological problems (p < 0.05); 42.8% of the immigrants had the Type 9 personality, and all personality types were affected by the Psychological Affection, Physical Affection, Anxiety, and Social Adaptation sub-dimensions, respectively (p < 0.05).By analysing the impact of migration-induced trauma on immigrants within their society, it can be recommended to implement initiatives specific to immigrants' personality traits and to carry out protective/preventive projects that will minimize immigrants' exposure to trauma and encourage their participation in social adaptation processes.

Affection

Psychological adaptation

Marital status

10.21101/cejph.a7651

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