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Eugen Osiac

University of Medicine and Pharmacy of Craiova

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G. Hüber

Universität Hamburg

S. Kück

Physikalisch-Technische Bundesanstalt

E. Heumann

Universität Hamburg

I. Sokólska

Center for Non-Communicable Diseases

Veronica Mercuţ

University of Medicine and Pharmacy of Craiova

A. Lupeǐ

National Institute for Laser Plasma and Radiation Physics

Monica Scrieciu

University of Medicine and Pharmacy of Craiova

Sanda Mihaela Popescu

University of Medicine and Pharmacy of Craiova

Bogdan Cătălin

University of Medicine and Pharmacy of Craiova

Dan Ionuƫ Gheonea

University of Medicine and Pharmacy of Craiova

Cooperative Institutions

University of Medicine and Pharmacy of Craiova

University of Craiova

National Institute for Laser Plasma and Radiation Physics

Yahoo (United Kingdom)

Institutul de Fizică Atomică

Carol Davila University of Medicine and Pharmacy

University of Bucharest

Hai phong University Of Medicine and Pharmacy

Universität Hamburg

Centre National de la Recherche Scientifique

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[Epidemiological evaluations of the incidence of posttransfusion hepatitis in Iaşi County in 1985-1995].

A Ivan Doina Azoicăi R Grigorescu I Mitroi I Iacob

In the interval 1985-1995 the morbidity rate of viral hepatitis of various causes showed yearly variations, an average of 181 cases being recorded. The performed investigations revealed markers for viral hepatitis B in an yearly average of 154 cases for the 11 years under study. Posttransfusion hepatitis had an average incidence of 43 cases per year, in 59.1% the markers for viral hepatitis B being absent. 93.3% of the cases with posttransfusion hepatitis belonged to the age groups over 20 years and workers presented a mean yearly incidence of 28.3% of all cases. In 1995 the blood donors with viral hepatitis C antibodies represented 4.05% and 75% of them belonged to the age groups 21-60 years, 50% of them being industrial workers and 40% having the A II blood group. Of the 321 admitted cases, 26.7% presented AgHBs, 8.4% AcVHC, in 2.3% markers for both viruses were evidenced and in 62.8% of the cases the diagnosis was made on epidemiological criteria and serologic exclusion (non A, B, C) without excluding the possible intervention of other hepatitic viruses.

Viral Hepatitis

Hepatitis B

Hepatitis C

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CELL MEMBRANE GPER AND ERα ON MYOMETRIUM: TWO DISTINCT RECEPTORS WITH DISTINCT SIGNALLING PATHWAYS

Oana Sorina Tica Elena Deliu Tudorel Ciurea Xīn Gào Eugen Osiac

The “rapid” effects of oestrogens on myometrium mainly result by activating cell membrane oestrogen receptors: ERα and GPER (G protein coupled oestrogen receptor 1). In contrast to the contractile effect induced by G-1 (GPER agonist), effect involving the opening of L-type calcium channels, oestradiol (E 2 ) inhibited until arrest the spontaneous contractile activity and significantly decreased the contraction induced by high K + or oxytocin. The effects of E 2 were not blocked by G-15 (GPER antagonist). We concluded that the “rapid” effects E 2 -induced on myometrium are the result of cell membrane ERα activation and mainly consist of the inhibition of L-type calcium channels. It is a sticking difference between the genomic and non-genomic effect of E 2 on oxytocin-induced signalling pathway. Finally, it is very probable a masking/inhibition (modulator) effect of ERα on cell membrane GPER activity.

GPER

Myometrium

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Pulsed Laser Ablation of the Solid Targets in a Liquid Environment

Annals of West University of Timisoara - Physics (2016)

Eugen Osiac Mihaela Dinu Mihaela Tinca Udriștioiu

Abstract In this paper, the viability of laser ablation of gold target immersed in medical distillated water used to produce nanoparticles having morphological, structural and compositional properties for medical applications is explored. The morphological properties were investigated by means of scanning electron microscopy (SEM). Energy-dispersive X-ray spectroscopy (EDX) analysis was used to reveal the composition of resulting particles. The absorbance in the wavelengths range of 300-800 nm can be assigned to the small gold nanoparticles.

Laser Ablation

Absorbance

Energy-dispersive X-ray spectroscopy

10.1515/awutp-2016-0007

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Evaluation Through the Optical Coherence Tomography Analysis of the Influence of Non-Alcoholic Fatty Liver Disease on the Gingival Inflammation in Periodontal Patients

Diabetes Metabolic Syndrome and Obesity (2021)

Petra Șurlin Andreea Cristiana Didilescu Luminița Lazăr Cristian Cosmin Arsenie Adrian Camen

The purpose of this ex vivo study is to exhibit the inflammatory changes that occur within the gingival tissue by using optical coherence tomography (OCT) in periodontal patients with non-alcoholic fatty liver disease (NAFLD) and if NAFLD could influence the local periodontal inflammation.Gingival tissue samples obtained from patients were divided into three groups - P (periodontitis), NAFLD+P (NAFLD+periodontitis) and H (healthy) groups - and were scanned using an OCT light beam, in order to perform a qualitative and quantitative analysis of images. The value of average pixel density has been associated with the degree of inflammation.The highest average pixel density was found in patients from the H group, while the lowest value of average pixel density was recorded in gingival tissue samples collected from patients with NAFLD+P. The image assessments from NAFLD+P group delivered lower values of average pixel density than those of P group, suggesting a possible influence of this disease on the inflammatory tissular changes produced by periodontal disease.After comparing the OCT analysis results obtained for the three groups of patients, we can consider that NAFLD may be an aggravating factor for the inflammation of periodontal disease.

10.2147/dmso.s310314

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Inhomogeneous broadening effects in optical spectra Nd/sup 3+/ in CNGG and CLNGG

A. Lupeǐ V. Lupeǐ L. Rogobete Eugen Osiac L. Gheorghe

Summary form only given. Interesting classes of solid state hosts for diode pumped lasers or for short pulse emission could be those with broad spectral bands. Although rare earth ions in glasses satisfy this condition, their use in diode pumped lasers is limited by the small stimulated emission cross section and thermal conductivity. Therefore, a crystal that fulfils all these three requirements is expected to give better performances. These characteristics could be satisfied by crystals with disordered structure such as calcium niobium gallium garnet Ca/sub 3/Nb/sub 1.6875/Ga/sub 3.187/O/sub 12/ (CNGG) and calcium lithium niobium gallium garnet Ca/sub 3/Nb/sub 1.775/Ga/sub 2.95/Li/sub 0.275/O/sub 12/ (CLNGG). These crystals have several advantages compared with ordered garnet crystals, such as YAG: low melting point (smaller than 1500/spl deg/C), broad absorption and emission bands, larger doping level with ions such as Nd/sup 3+/, better thermal properties than glasses. Though laser emission was reported for Nd/sup 3+/ in CNGG and CLNGG, the growth conditions for homogeneous crystals or fibres, the spectroscopic characteristics, the nature of nonequivalent centers, and the energy transfer peculiarities are still problems to investigate. The paper attempts to elucidate the nature of non-equivalent Nd/sup 3+/ centers leading to Nd/sup 3+/ multisites in both crystals, CNGG and CLNGG, and to discuss the energy transfer processes.

Crystal (programming language)

Neodymium

10.1109/cleoe.2000.910402

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Pump wavelengths for an Er:YLiF4 green-emitting laser

Optical Materials (2006)

O. Toma Eugen Osiac S. Georgescu

Photon Upconversion

Rate equation

Optical Pumping

10.1016/j.optmat.2006.11.023

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Green upconverted emission by infrared pump in Ho3+-doped YAlO3

Journal of Alloys and Compounds (2002)

Photon Upconversion

Rate equation

10.1016/s0925-8388(02)00103-2

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Diode pumping of a continuous-wave Pr^3+-doped LiYF_4 laser

Optics Letters (2004)

André Richter E. Heumann Eugen Osiac G. Hüber Wolf Seelert

We report, for the first time to our knowledge, diode-pumped cw laser oscillation of Pr3+:LiYF4 in the red spectral range. The pump power is provided by a GaN laser diode emitting a maximum output power of 25 mW at a wavelength of approximately 442 nm. The Pr3+ laser emits 1.8 mW of output power at a 639.7-nm wavelength. Threshold pump power and slope efficiency in a nonoptimized setup are determined to be 5.5 mW and 24%, respectively.

Continuous wave

Optical Pumping

Laser diode

Slope efficiency

10.1364/ol.29.002638

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Citations (171)

Characterization of stationary and pulsed inductively coupled RF discharges for plasma sterilization. Invited paper

Timo Gans Eugen Osiac Deborah O’Connell V. A. Kadetov Uwe Czarnetzki

Characterization

Sterilization

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Terawatt laser system irradiation of carbon/tungsten bilayers

physica status solidi (a) (2012)

C.P. Lungu Aurelian Marcu C. Poroşnicu I. Jepu A.M. Lungu

Abstract Using the original thermionic vacuum arc method (TVA), carbon films with the thickness of about 2500 nm were coated on top of 200 nm tungsten films deposited on fine grain graphite substrates. The carbon/tungsten bilayers were irradiated using a terawatt laser system (TEWALAS), 360 ps and 100 fs pulse duration, 110–150 mJ pulse energy. The analysis of the selected area electron diffraction (SAED) pattern allowed the identification of rhomboedral structures corresponding to diamond. The Raman scattering measurements were also performed on the produced craters and the specific peak at 1330 cm −1 corresponding to diamond was observed. The CC sp 3 bonding content increased to 39.4% in the irradiated region compared to 30.8% in the “as deposited” zone, as shown by XPS. The craters produced by the laser irradiation were morphologically studied using optical imaging and scanning electron microscopy.

Selected area diffraction

Carbon fibers

10.1002/pssa.201200046

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