Yuan Deng

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccwkhhd

Cite

Citations (0)

CCDC 1043496: Experimental Crystal Structure Determination

The Cambridge Structural Database (2015)

Lian Yu Yuan Deng Jian Cao

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc140v55

Cite

Citations (0)

CCDC 285876: Experimental Crystal Structure Determination

The Cambridge Structural Database (2009)

Yingxia Song Shu Zhang Yuan Deng Suyun Jie Lijun Li

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc9lgt4

Cite

Citations (0)

CCDC 983590: Experimental Crystal Structure Determination

The Cambridge Structural Database (2014)

Yuan Deng Yuanyuan Cheng Hui Liu J. E. Mack Hua Lu

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cc120hq9

Cite

Citations (0)

CCDC 2022856: Experimental Crystal Structure Determination

The Cambridge Structural Database (2020)

Li Li Bing Zhu Yuanyuan Cheng Yuan Deng

10.5517/ccdc.csd.cc25wyfg

Cite

Citations (0)

CCDC 621104: Experimental Crystal Structure Determination

The Cambridge Structural Database (2007)

Suyun Jie Shu Zhang K. Wedeking Wen Zhang Hongwei Ma

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccnv9md

Cite

Citations (0)

CCDC 870965: Experimental Crystal Structure Determination

The Cambridge Structural Database (2013)

Miaomiao Xue Liyuan Ding Liya Lin Yahong Lu Bairong He

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccy79n3

Cite

Citations (0)

Vacancy modulation on NiTi-layered double hydroxides towards highly selective CO2 photoreduction

Applied Catalysis B Environment and Energy (2024)

Congjia Luo Zeyang Li Yuan Deng Lei Wang Enze Xu

Layered double hydroxides

Nickel titanium

Modulation (music)

10.1016/j.apcatb.2024.124156

Cite

Citations (2)

CCDC 1002368: Experimental Crystal Structure Determination

The Cambridge Structural Database (2015)

Long‐Sheng Zheng Yun‐Long Wei Kezhi Jiang Yuan Deng Zhan‐Jiang Zheng

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

Crystal (programming language)

10.5517/cc12n1g7

Cite

Citations (0)

Zinc deficiency triggers ribosome remodeling to reverse biofilm azole resistance in Candida albicans

Research Square (Research Square) (2025)

Yingzhe Wang Shigan Ye Yuan Deng Yingting Huang Xiaoliang Zhu

Abstract Biofilm formation is a key cause of high azole resistance and prolonged infection in Candida albicans. Zinc ion is involved in the regulation of biofilm formation and azole resistance in C. albicans, but its specific role remains unknown. We assessed the alteration of azole resistance in C. albicans biofilm in vivo and in vitro by inducing zinc deficiency, and found that zinc deficiency inhibits biofilm formation, reduces the activity of efflux pumps, enhances cellular metabolism levels, reduces in vivo pathogenicity, and ultimately reverses azole resistance. RNA-seq showed that zinc deficiency promotes cell survival under zinc deficiency by triggering intracellular ribosome remodeling, and downregulates the expression of genes related to biofilm core transcription factors and efflux pumps and upregulates the expression of genes related to glucose metabolism. This study provides new insights into the treatment of clinical C. albicans infections, particularly biofilm-associated highly resistant and persistent infections, by targeting zinc.

Azole

10.21203/rs.3.rs-5862334/v1

Cite

Citations (0)

Papers

Citation

H-Index

i-10 index

Papers

Citation

H-Index

i-10 index