P. Schollmeyer

Karlsruhe Institute of Technology

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Christoph Wanner

University of Würzburg

Walter H. Hörl

Medical University of Vienna

G. Hoppe‐Seyler

Intelligent Transport Systems Niedersachsen

Joachim Böhler

Deutsche Klinik für Diagnostik

Hermann Pavenstädt

University Hospital Münster

E. Keller

University of Zurich

B. Krumme

Deutsche Klinik für Diagnostik

H. B. Steinhauer

University of Freiburg

R. Greger

University of Freiburg

Lars Christian Rump

Heinrich Heine University Düsseldorf

Cooperative Institutions

University of Freiburg

298

University Medical Center Freiburg

230

Heidelberg University

117

Pediatric Nephrology of Alabama

University of Tübingen

Ludwig-Maximilians-Universität München

Goethe University Frankfurt

Medizinische Hochschule Hannover

University Hospital Heidelberg

University of Würzburg

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

EXTRACTION OF FREE FATTY ACIDS BY THE HUMAN KIDNEY

H. Nieth Frederick G. Duerr M. Eggstein B Hoermann P. Schollmeyer

Source

Cite

Citations (0)

Urinary proteinase activity in patients with multiple traumatic injuries, sepsis, or acute renal failure.

PubMed (1986)

C. Wanner P. Schollmeyer Hörl Wh

Proteolytic enzymes

Source

Cite

Citations (11)

Quiz of the Month

American Journal of Nephrology (1988)

K. Schaefer D. von Herrath Christiane M. Erley A. Böhle E. Biwer

10.1159/000167587

Cite

Citations (0)

Late Manifestation of Autosomal-Recessive Polycystic Kidney Disease in Two Sisters

American Journal of Nephrology (1988)

Hartmut P.H. Neumann Klaus Zerres Carl L. Fischer G. Wolff Hans E. Schaefer

We report on 2 siblings with autosomal-recessive polycystic kidney disease, diagnosed at the ages of 14 and 18 years, respectively. Clinical findings and differential diagnosis, especially for autosomal-dominant polycystic kidney disease, are given. The consequences for genetic counselling are discussed.

10.1159/000167582

Cite

Citations (15)

Renal functional reserve in elderly patients.

PubMed (1993)

Joachim Böhler D Glöer P. Reetze-Bonorden E. Keller P. Schollmeyer

The concept of renal functional reserve (RFR) is used in the evaluation of renal function in health and disease. RFR is defined as the difference between glomerular filtration rate (GFR) at rest and the maximum GFR for example under stimulation by an amino acid infusion or a protein rich meal. GFR decreases normally with age by about 1 ml/min per year. The purpose of this study was to establish the effect of the GFR decrease with age on absolute and relative values of RFR. We investigated 12 hospitalized patients 60 to 85 years of age (mean 74 +/- 2.0 SEM) recovering from nonrenal disease. On two consecutive days, inulin and paraaminohippuric acid (PAH) clearance was performed over a period of 4 hours. On day A patients received 1 liter of a 5% glucose solution i.v. On day B an equal volume of an amino acid solution (2 mg/kg/min) was given. In these elderly patients baseline GFR without stimulation measured 73.2 +/- 7.9 ml/min per 1.73 m2 and stimulated GFR was 99.1 +/- 8.5 ml/min, a 35.3% increase (p < 0.025). Thus, renal functional reserve measured 25.9 +/- 8.7 ml/min. PAH clearance increased from 329.0 +/- 41.9 ml/min per 1.73 m2 to 438.8 +/- 50.3 ml/min (p < 0.025). These data confirm that baseline GFR is lower in the elderly compared to young adults. However, renal functional reserve is well maintained in elderly human subjects. This suggests that glomerulosclerosis of aging may not be the only explanation for the low baseline GFR in the elderly.(ABSTRACT TRUNCATED AT 250 WORDS)

Liter

Source

Cite

Citations (23)

Treatment of Ostial Renal-Artery Stenoses with Vascular Endoprostheses after Unsuccessful Balloon Angioplasty

New England Journal of Medicine (1997)

Ulrich Blum B. Krumme Peter Flügel Andreas Gabelmann T Lehnert

Percutaneous transluminal renal angioplasty is a safe and effective treatment for nonostial stenoses of the renal arteries, but it has proved to be disappointing for ostial stenoses. Therefore, we prospectively studied the use of intravascular stents for the treatment of critical ostial stenoses after unsuccessful balloon angioplasty.Stainless-steel endoprostheses were placed across 74 renal-artery stenoses located within 5 mm of the aortic lumen in 68 patients with hypertension. Twenty patients had mild or severe renal dysfunction. The indications for stent placement were elastic recoil (63 arteries) or dissection (1 artery) of the vessel after angioplasty, or restenosis after initially successful balloon angioplasty (10 arteries). Patients were followed for a mean of 27 months with measurements of blood pressure and serum creatinine, duplex sonography, and intraarterial angiography.Initial technical success was achieved in all patients. Minor complications (local hematomas) occurred in only three patients; there were no major complications. Eighty-four percent of the patients were free of primary occlusion 60 months after the procedure. Restenosis of more than 50 percent of the vessel diameter occurred in 8 of 74 arteries (11 percent). Reintervention resulted in a secondary patency rate of 92 percent. Long-term normalization of blood pressure was achieved in 11 patients (16 percent). Serum creatinine levels did not change significantly after successful stent implantation in patients with previously impaired renal function.Accurate placement of renal-artery stents is technically feasible without major complications. The favorable early and long-term results suggest that primary stent placement is an effective treatment for renal-artery stenosis involving the ostium.

Cutting balloon

Lumen (anatomy)

10.1056/nejm199702133360702

Cite

Citations (521)

BONE FRACTURE AND OSTEODENSITOMETRY WITH DUAL ENERGY X-RAY ABSORPTIOMETRY IN KIDNEY TRANSPLANT RECIPIENTS

Transplantation (1994)

Wolfgang Grotz F. Mundinger Bernd Gugel V. Exner Günter Kirste

Kidney transplant recipients have multiple factors leading to osteoporosis. The purpose of this study was to determine the fracture rate after kidney transplantation and the significance of osteodensitometry with dual energy x-ray absorptiometry (DXA) in identifying the risk patients. Bone mineral density (BMD) was measured with DXA in 100 graft recipients (mean interval 63±53 months after transplantation) and correlated with the incidence of fractures. Fracture rate of peripheral bones increased from 0.009 before transplantation and 0.012 on hemodialysis to 0.032 fractures per patient and year after transplantation. Seventeen fractures of peripheral bones occurred in 11% of the patients within a mean of 103±59 months after transplantation. Three additional patients had fractures of the lumbar spine. Patients with fractures were characterized by low or low-normal BMD (0.93±0.23 versus 1.04±0.17 g/cm2 at lumbar spine), a frequent history of parathyroidectomy (21% versus 6%), and a longer transplant interval (103±59 versus 57±49 months). Fractures occurred in patients with low and normal BMD. DXA at the femoral neck proved to be of no value to define patients at risk of fractures. DXA at the lumbar spine also proved to be of limited value for this question. Therefore, alternatively, more sensitive methods of BMD and of bone architecture measurements are necessary for identifying the kidney transplant recipients at risk of fracture.

Dual-Energy X-ray Absorptiometry

10.1097/00007890-199410270-00009

Cite

Citations (217)

Beclobrate: Pharmacodynamic properties and therapeutic use in hyperlipidemia

European Journal of Clinical Pharmacology (1991)

Christoph Wanner Heinrich Wieland P. Schollmeyer W. H. H�rl

Pharmacodynamics

Hyperlipidemia

10.1007/bf01409416

Cite

Citations (6)

Kidney Independent Serine Synthesis in the Rat

The Nephron journals/Nephron journals (1985)

Walter H. Hörl R. Kluthe Paul Gierlach P. Schollmeyer

The potential role ofthe kidney in renal serine synthesis was elucidated in rats following dietary serine as well as serine and glycine depletion for 6 weeks. Serine deficient diet caused a significant rise in blood serine and glycine values. In contrast, blood glycine concentration decreased significantly following serine and glycine depletion, whereas blood serine levels remained unchanged. Bilateral nephrectomy caused a significant decrease of blood serine values of control and serine deficient rats. Serine concentration, however, was not affected by bilateral nephrectomy following serine and glycine deficiency indicating kidney-independent serine synthesis under these conditions. There was a significant increase of blood lactate and pyruvate levels under serine and serine/glycine deficient diet compared with control animals, whereas blood ketone bodies fell. In contrast, 24 h after bilateral nephrectomy blood ketone bodies rose and blood lactate and pyruvate concentrations decreased significantly. 24 h after bilateral nephrectomy there was a marked rise in blood citrate values of female rats compared with male animals indicating sex dependency of kidney citrate metabolism in the rat.

10.1159/000183490

Cite

Citations (3)

Urinary Concentration and Dilution

Springer eBooks (1969)

Jürgen Schnermann Heinz Valtin H. Fischbach Wolfram Nagel M. Horster

Loop of Henle

Renal sodium reabsorption

10.1007/978-3-642-87957-9_5

Cite

Citations (28)