Shahrbanoo Oryan

Kharazmi University

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Akram Eidi

Islamic Azad University, Science and Research Branch

Mohammad‐Reza Zarrindast

Tehran University of Medical Sciences

Delaram Eslimi Esfahani

Kharazmi University

Kazem Parivar

Islamic Azad University, Science and Research Branch

Alireza Komaki‬

Hamedan University of Medical Sciences

Jalal Solati

Islamic Azad University, Karaj

Jalal Zaringhalam

Shahid Beheshti University of Medical Sciences

Abolhassan Ahmadiani

Shahid Beheshti University of Medical Sciences

Mohammad Nabiuni

Kharazmi University

Leila Dargahi

Shahid Beheshti University of Medical Sciences

Cooperative Institutions

Kharazmi University

Tehran University of Medical Sciences

Islamic Azad University, Science and Research Branch

Shahid Beheshti University of Medical Sciences

University of Tehran

Islamic Azad University, Tehran

Iran University of Medical Sciences

Tarbiat Modares University

Shahid Beheshti University

Mashhad University of Medical Sciences

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Role of serotonergic system on modulation of depressogenic-like effects of silymarine.

PubMed (2012)

Parichehreh Yaghmaei Shahrbanoo Oryan Khadijeh Mohammadi Jalal Solati

In the present study, we have investigated the effects of silymarine on depression and the possible role of serotonergic system in these effects. The rats were anesthetized intraperitoneally with ketamine hydrochloride and placed in a Stoelting stereotaxic instrument. A stainless steel guide cannula (22-gauge) was implanted in the third ventricular region. The third ventricular region was infused by means of an internal cannula (27-gauge), terminated 1 mm below the tip of the guide cannula. Forced swimming test was used for evaluating the depression. The results obtained from this study showed that oral administration of silymarin (35, 70, 140 and 280 mg/rat) for two weeks increased the immobility time in forced swimming test, indicating an increase in depression level of the treated rats. Intra-third-ventricle (Intra-TV) infusion of 5HT1A receptor agonist 8-OH-DPAT (25 and 10 ng/rat) decreased the immobility time indicating an anti-depression effect, while injection of 5HT1A receptor antagonist NAN190 (0.25, 0.5 and 1 μg/rat) had no significant effect on immobility time. An effective dose of 8-OH-DPAT (10 ng/rat) co-administered with silymarin (140 and 280 mg/rat) decreased the depressogenic effects of silymarin. These results showed that the depressogenic effects of silymarin may be modulated via 5HT1A receptor of serotonin.

8-OH-DPAT

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Citations (7)

The effect of hepatic impairment on the aquaporin-4 in the paraventricular (PVN) and Supraoptic (SON) nuclei of rat hypothalamus

Medical Science Journal of Islamic Azad Univesity - Tehran Medical Branch (2017)

Delaram Eslimi Esfahani Shahrbanoo Oryan Mohammad Nabiuni Manijeh Karimian Peiro Karimian Peiro Fatemeh Gharooni

Supraoptic nucleus

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Citations (1)

Possible involvement of ATP-sensitive potassium channels in the antidepressant-like effect of baclofen in mouse forced swimming test

Pharmacological Reports (2016)

Seyedeh Khadijeh Nazari Vahid Nikoui Sattar Ostadhadi Zahra Chegini Shahrbanoo Oryan

Baclofen

10.1016/j.pharep.2016.07.006

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Citations (20)

The neuroprotective effect of MicroRNA-149-5p and coenzymeQ10 by reducing levels of inflammatory cytokines and metalloproteinases following focal brain ischemia in rats

Brain Research Bulletin (2021)

Elham Ghasemloo Shahrbanoo Oryan Mohammad Reza Bigdeli Hossein Mostafavi Mehdi Eskandari

Brain ischemia

10.1016/j.brainresbull.2021.01.013

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Citations (23)

The involvement of kisspeptin in centrally regulatory mechanism of neuropeptide Y on testosterone secretion in male Wistar rats

Physiology and Pharmacology (2016)

Vahid Azizi Shahrbanoo Oryan Homayoun Khazali Abdolkarim Hosseini

Kisspeptin

Adult male

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Effect of morphine, naloxone and histamine system on water intake in adult male rats

European Journal of Pharmacology (2003)

Maryam Eidi Shahrbanoo Oryan Akram Eidi Leili Sepehrara

Pyrilamine

Histaminergic

10.1016/j.ejphar.2003.07.001

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Citations (16)

Visfatin Inhibits Apoptosis and Necrosis of Hippocampus CA3 Cells Following Transient Global Ischemia/Reperfusion in Rats

International Journal of Peptide Research and Therapeutics (2014)

Sohaila Erfani Nahid Aboutaleb Shahrbanoo Oryan Nabi Shamsaei Mehdi Khaksari

10.1007/s10989-014-9449-1

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Citations (27)

Downregulation of Extracellular Matrix and Cell Adhesion Molecules in Cumulus Cells of Infertile Polycystic Ovary Syndrome Women with and without Insulin Resistance.

PubMed (2019)

Fatemeh Hassani Shahrbanoo Oryan Poopak Eftekhari‐Yazdi Masood Bazrgar Ashraf Moini

10.22074/cellj.2019.5576

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Citations (30)

Effects of Hippocampal Microinjection of Irisin, an Exercise-Induced Myokine, on Spatial and Passive Avoidance Learning and Memory in Male Rats

International Journal of Peptide Research and Therapeutics (2019)

Saeed Mohammadi Shahrbanoo Oryan Alireza Komaki‬Akram Eidi Mohammad Zarei

Myokine

FNDC5

10.1007/s10989-019-09842-2

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Citations (14)

Antinociceptive and Anti-inflammatory Effects of Hydroalcoholic Extract of Female Cones of Juniper (Juniperus excelsa) and Plantago ovata in Male Wistar Rats

Qom Univ Med Sci J (2019)

Mohadese Shekari Sareh Gorgi Maryam Rahimi Tesiye Farhad Valizadegan Shahrbanoo Oryan

Antinociceptive and Anti-inflammatory Effects of Hydroalcoholic Extract of Female Cones of Juniper (Juniperus excelsa) and Plantago ovata in Male Wistar Rats

Plantago ovata

Cupressaceae

Plantago

Juniperus communis

Plantaginaceae

10.29252/qums.13.7.62

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