Zr doped NBT-BZT(94Na 0.5 Bi 0.5 TiO 3 -6BaZr x T 1-x O 3 ) (x=0.1) powder was synthesis with solid-state method. The sintering process was carried out at between 1035 to 1180°C in air for 2h. The crystal phase and microstructure of the ceramics were characterized using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The influence of Zr content on the piezoelectric and energy harvesting performance were investigated and compared with PZT4, PZT5H. Ferroelectric and piezoelectric properties of NBT-BZT ceramics were obtained with impedance/gain phase analyzer. The results showed that, the best electrical properties were obtained at 1150°C. Also, energy harvesting potential of cymbal form of NBT-BZT materials were greater than disc (bulk) form.
Doxorubicin is a chemotherapeutic agent used in a wide spectrum of cancers. However, cardiotoxic effects have limited its clinical use. The early detection of doxorubicin-induced cardiotoxicity is crucial. The purpose of our study was to assess values of Doppler and tissue Doppler imaging (TDI)-derived myocardial performance index (MPI) in adult cancer patients receiving doxorubicin treatment.A total of 45 patients underwent echocardiographic examinations before any doxorubicin had been administered and then after doxorubicin. Doppler and TDI-derived MPI of left ventricular (LV) were determined in the evaluation of cardiotoxicity. Additionally, TDI-derived MPI of right ventricular (RV) was determined.All patients underwent control echocardiographic examination after mean 5 ± 1.7 months. The LV MPI obtained by both Doppler and TDI were increased after doxorubicin treatment (0.56 ± 0.11, 0.61 ± 0.10, p = 0,005 vs 0.51 ± 0.09, 0.59 ± 0.09, p = 0.001, respectively). There was no correlation between Doppler-derived MPI and cumulative doxorubicin dose (coefficient of correlation 0.11, p = 0.6). TDI-derived MPI was correlated with cumulative doxorubicin dose (coefficient of correlation 0.35, p = 0.015), but this correlation is weak (r = 0.38). The study population was divided into two groups according to doxorubicin dose (below and above 300 mg level). There was a moderate correlation between TDI-derived MPI and less than 300 mg of doxorubicin dose (coefficient of correlation 0.51, p = 0.028). However, Doppler-derived MPI was not correlated with less than 300 mg of doxorubicin dose (coefficient of correlation 0.38, p = 0.123). Also, there was no significant change in the TDI-derived RV-MPI (0.49 ± 0.14, 0.50 ± 0.12, p = 0.56).TDI-derived MPI is a useful parameter and an early indicator compared with Doppler-derived MPI in the detection of cardiotoxicity during the early stages. Also, doxorubicin administration does not affect RV function.
Birleşmiş Milletlere göre 2021 yılında 7,9 milyar olan Dünya nüfusu, 2100 yılında %38 artarak 11 milyara yaklaşacaktır. Artan küresel ısınma ve onun ortaya çıkardığı olumsuz gıda üretim koşulları, sınırlı tarımsal alanlar, artan atıklarla birlikte çevre kirliliği; çevreye duyarlı uygulamaları daha da önemli hale getirmektedir. Türkiye’de çevreye duyarlı tesis olarak sertifikalandırılan yeşil oteller ve uygulamaları da çevreye duyarlılık noktasında önemlidir. Bu bağlamda, araştırma Ankara’daki yeşil otel restoranlarının çevreye duyarlı uygulamalarını, mutfak yöneticileri gözünden değerlendirmeyi amaçlamaktadır. Ankara’daki 14 yeşil otelde yüz yüze görüşme tekniğiyle verilerin toplandığı araştırmada yeşil otellerin restoran mutfaklarında çevreye duyarlı uygulamalardan; atık yönetimi, sürdürülebilir gıda, su ve çevreye duyarlılık ile müşteri boyutları incelenmiştir. Çalışmada, nitel durum çalışma deseni kullanılmış, katılımcıların görüşleri alınarak, betimsel analizleri yapılmıştır. Araştırmaya göre en çok atık madde taze sebze ve meyve kabuklarından oluşmaktadır. Gıda atıklarının oluşum nedenleri arasında ilk sırayı açık büfeler almaktadır. Tüm mutfak yöneticilerinin yerel ürün tedarikine bakışı olumlu ve destekler niteliktedir. İşletmelerde en çok su tüketimi, mutfakta ürün hazırlığında olmaktadır.
From 1993 to 1998, 19 patients with mediastinal tuberculosis underwent mediastinoscopy without any demonstrable parenchymal lesion and with negative diagnostic bronchoscopy. The mean age was 34.4 years (range, 15 to 67 years) and 10 were male. The most common symptom was cough in 12 patients, 4 were asymptomatic. Computed tomography showed involvement of the right paratracheal nodal station in 8 cases. Multiple biopsies of 3 to 5 mediastinal nodal stations diagnosed tuberculous lymphadenitis in 16 patients; in 5 of these, nonspecific inflammatory nodes were also sampled. In 3 patients who had biopsies of 1 mediastinal nodal station, the diagnosis could not be established. It was concluded that when used effectively, mediastinoscopy was acceptable as a final diagnostic step in patients with mediastinal tuberculous lymphadenitis.
Objectives Both metabolic syndrome (MetS) and nondipping status (insufficient reduction in nocturnal blood pressure) have been linked with target organ damage. We evaluated the effect of nondipping status on target organ damage in subjects with MetS. Study design Eighty-two patients diagnosed as having MetS were divided into two groups according to the findings of 24-hour ambulatory blood pressure monitoring as dipper (n=35, 19 women, 16 men; mean age 48.4+/-6.4 years) and nondipper (n=47, 35 women, 12 men; mean age 50.4+/-4.7 years). Cardiac damage was assessed by conventional and tissue Doppler echocardiography, and renal damage by 24-hour urinary albumin excretion. Results The two groups were similar with regard to age, body mass index, presence of diabetes, smoking, clinical and 24-hour, daytime and nighttime blood pressures, plasma lipid profile, distribution of and the mean total number of MetS criteria. The ratio of early (Em) to late (Am) left ventricular peak diastolic myocardial velocities (Em/Am) was significantly lower in nondippers (p=0.016). Nondippers also had higher values of left ventricular mass index, myocardial performance index, and 24-hour urinary albumin excretion, but these differences did not reach a significant level (p=0.110, p=0.099, p=0.093, respectively). Multivariate regression analysis showed increasing age and nondipping status as independent factors associated with decreased Em/Am ratio (beta=-0.25, p=0.020 and beta=-0.22, p=0.042, respectively). Conclusion In subjects with MetS, nondipping status may be associated with both cardiac and renal damage independent of other components of MetS. Since the degree of diastolic dysfunction is more marked than that of albuminuria in nondippers, it may be extrapolated that the extent of cardiac damage surpasses renal damage in these subjects.
