Md Shahadat Hossain

Bangabandhu Sheikh Mujibur Rahman Science and Technology University

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Md Asadul Islam

Sunway University

Abu Shara Shamsur Rouf

University of Dhaka

M S Islam

University of Dhaka

Prasanta Kumar Chakraborty

National Institute of Cancer Research and Hospital

Md Ruhul Amin

Bangabandhu Sheikh Mujib Medical University

Md. Jahidul Islam

Bangladesh University of Engineering and Technology

Ahasanul Haque

International Islamic University Malaysia

Sohely Rahman

Dhaka Medical College and Hospital

Md Jahidul Islam

University of Florida

Subrata Bhadra

University of Dhaka

Cooperative Institutions

Dhaka Medical College and Hospital

Bangabandhu Sheikh Mujib Medical University

University of Dhaka

National Institute of Cardiovascular Diseases

Shaheed Suhrawardy Medical College

International Islamic University Malaysia

Universiti Putra Malaysia

National Institute of Neurosciences & Hospital

Swinburne University of Technology Sarawak Campus

National Institute of Traumatology & Orthopaedic Rehabilitation

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Role of Baclofen in Combination with Intensive Rehabilitation in Spastic Cerebral Palsy

Journal of National Institute of Neurosciences Bangladesh (2015)

Md Ruhul Amin Sohely Rahman Narayan Chandra Saha Md Shahadat Hossain Md Jahidul Islam

Background: The treatment of cerebral palsy is multifactorial.Objective: In this study we find out the combined efficacy of baclofen and intensive rehabilitation in the treatment of spastic cerebral palsy.Methodology: This observational study was conducted over 30 patients in Dhaka Medical College Hospital from January 2011 to December 2011.The patient satisfying the inclusion and exclusion criteria was randomly enrolled in this study. They received Baclofen orally two times daily according to the body weight regularly in combination with intensive rehabilitation 1 hour daily five times a week for 24 weeks. All patients were followed up at 4 weeks interval and were evaluated for a total of 24 weeks.Result: Combination of Baclofen and intensive rehabilitation is effective in reducing tone in spastic cerebral palsy by using Modified Ashworth scale (p<0.05). Combination of Baclofen and intensive rehabilitation is also effective in joint angle improvement in spastic cerebral palsy measured by physician rating scale crouch (p<0.05) and foot contact, (p<0.05) and also improvement in gross motor function (p <0.05).Conclusion: For reduction of generalized spasticity regarding muscle tone, range of motion of the joint and improvement of gait in cerebral palsy patients, combination of Baclofen and intensive rehabilitation may be used.J. Natl Inst. Neurosci Bangladesh 2015;1(1):18-21

Baclofen

Muscle tone

Modified Ashworth scale

Spastic cerebral palsy

10.3329/jninb.v1i1.22943

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Medical Rehabilitation Services in Bangladesh: Problems & Challenges

Journal of Shaheed Suhrawardy Medical College (2019)

Md Shahadat Hossain

Abstract not available J Shaheed Suhrawardy Med Coll, June 2019, Vol.11(1); 1-2

10.3329/jssmc.v11i1.43169

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Quantitation of Sitagliptin in Drug Product by Validated Reversed Phase Liquid Chromatographic Technique

Dhaka University Journal of Pharmaceutical Sciences (2018)

Sharifa Sultana Md Shahadat Hossain M S Islam Abu Shara Shamsur Rouf

A novel reversed phase ultra-high performance liquid chromatographic (RP-UHPLC) method was developed for the estimation of sitagliptin in pharmaceutical dosage form. Separation was done by a X-bridge C18 column (4.6 i.d.× 150 mm, 5 μm particle size) with a flow rate of 1 ml/min using phosphate buffer (pH 6) and acetonitrile (70:30, v/v) as mobile phase at 268 nm using photodiode array plus (PDA+) detector. The retention time was found at 4.607 min. The developed method was validated as per the requirements of ICH-Q2B guidelines for specificity, system suitability, linearity, precision, accuracy, sensitivity and robustness. The linear regression analysis data for the linearity plot showed correlation coefficient values of 0.999 with LOD value of 0.06 μg/ml and LOQ of 0.225 μg/ml. The relative standard deviation (%RSD) for inter-day and intra- day precision was not more than 2.0%. The method was found to be accurate with percentages recovery of 98.50±0.03 to 99.70±0.05 and the % RSD was less than 2. The results showed that the proposed method is highly convenient for routine analysis of sitagliptin.Dhaka Univ. J. Pharm. Sci. 17(1): 123-129, 2018 (June)

Chromatographic Separation

Linearity

Retention time

Phosphate buffered saline

Sitagliptin Phosphate

10.3329/dujps.v17i1.37128

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Citations (5)

HbA1c and Troponin-I Levels and Their Relationship in Patients with Acute Coronary Syndrome.

PubMed (2023)

Md Shahadat Hossain Fariba Sharmin Ive Sultana M R Faysal S Begum

Acute coronary syndrome is a growing public health concern. Diabetic patients are more vulnerable to develop acute coronary syndrome due to accelerated atherosclerosis. Acute coronary syndrome is common in diabetes mellitus and is a major cause of mortality and morbidity in these patients. Troponin-I is a biochemical marker for cardiac muscle injury. Elevated glycated hemoglobin (HbA1c) is also regarded as an independent risk factor for acute coronary syndrome in patients with diabetes mellitus.The aim of this study was to assess the relationship of HbA1c and Troponin-I level in patients with acute coronary syndrome. This cross-sectional study was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka, Bangladesh from July 2018 to June 2019. Total study subjects were ninety five of both gender selected from the admitted patients of the cardiology department of the National Institute of Cardiovascular Diseases (NICVD), Dhaka. Diagnosis of acute coronary syndrome was confirmed by cardiologist. Diagnosis of diabetes mellitus was confirmed by Random Blood Glucose (RBG) level. Study subjects were grouped, acute coronary syndrome with diabetes mellitus as Group A and acute coronary syndrome without diabetes mellitus as Group B. Baseline parameters was recorded in data collection sheet. HbA1c, Troponin-I level of all study subjects were analyzed and recorded. Mean age of the study subjects in Group A and Group B were 51.06 years and 51.66 years respectively. Male gender was predominant in both groups. Mean SBP and DBP were significantly higher in Group A than Group B. Mean HbA1c level of the study subjects in Group A was significantly higher than Group B (p=0.001). Mean Troponin-I level in Group A was also significantly higher than Group B (p=0.023). HbA1c and Troponin-I levels were positively correlated in Group A (r=0.471, p=0.001). The present study demonstrated significant positive correlation of HbA1c and Troponin-I level in diabetic patients with acute coronary syndrome.

Glycated hemoglobin

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Comparison of trabeculectomy with mitomycin-C versus medical treatment in moderate stage of steroid induced glaucoma.

PubMed (2013)

Nazia Khan M A Khaleque Md Shahadat Hossain M S Islam M S Uddin

This prospective, comparative and interventional study was done to compare the effects of Trabeculectomy with Mitomycin-C and medical treatment with Timolol maleate 0.5% by controlling IOP (intra ocular pressure) and assessing the visual acuity (VA) and mean sensitivity (MS) of visual field in moderate stage of steroid induced glaucoma and conducted in the Department of Ophthalmology, Bangabandhu Sheikh Mujib Medical University, Dhaka, from July 2004 to June 2009. Sixty eyes of thirty patients with glaucoma due to use of topical steroids for >1 year. IOP range was 22-30 mm of Hg, visual field with (MD) mean deviation >6 to 12 dB and (MS) mean sensitivity >12-21dB, C:D ratio 0.7-0.8 and visual acuity 6/9 to 6/6 were included in this study. At first, topical steroid was stopped. Sample was collected in lottery method. Patients were divided into two groups. In Group I, 30 eyes were treated with Timolol maleate 0.5%. In Group II, 30 eyes were treated surgically by Trabeculectomy with Mitomycin-C. Follow-up were done on 1st POD, after 7 days, 1 month, 3 months and 6 months. Successful IOP control (<15mm of Hg) were achieved in 23 eyes (77%) in Group I and 30 eyes (100%) in Group II and were highly significant (p<0.001). Visual acuity and mean sensitivity also improved more in Group II than the Group I. It was also highly significant (p<0.001). So, Trabeculectomy with mitomycin-C is effective procedure in comparison to medical treatment for steroid induced glaucoma.

Mitomycin C

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Moderating role of psychological empowerment on the relationship between green HRM practices and millennial employee retention in the hotel industry of Bangladesh

Business Strategy & Development (2021)

Md Asadul Islam Dieu Hack‐Polay Ahasanul Haque Mahfuzur Rahman Md Shahadat Hossain

Abstract The purpose of the paper is to examine the relationship between green human resource management (GHRM) practices such as green recruitment, green training, green performance management, green reward, green involvement and millennial employee retention in the hotel industry in Bangladesh. The study examined the moderating effect of psychological empowerment on the relationship between GHRM practices and millennials' retention. This study used a survey questionnaire of 394 employees in Bangladeshi 3‐star to 5‐star hotels to test hypotheses using SmartPLS. The study found that green reward and green training have significant relationships with millennials' retention in hotels. The results showed psychological empowerment as a significant moderator on the relationship between three GHRM practices, green training, green performance management, green and reward and millennials' retention. With significant environmental degradation in South‐Asia, this study establishes GHRM can reconcile environmental regeneration and business strategy in the hotel industry, whose environmental footprint is increasingly under scrutiny.

Moderation

Employee retention

10.1002/bsd2.180

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Citations (45)

Rehabilitation Infrastructure and Services in a Tertiary Hospital in Bangladesh

KYAMC Journal (2020)

Md Israt Hasan Mohammed Emran Md Atiquzzaman Md Shahadat Hossain Taufiq Morshed

Background: Rehabilitation Medicine is the focal point on the refurbishment of the health and function, and reintegration of the patient into the community. Since inception, department of Physical Medicine and Rehabilitation (PMR) is dispensing state of the art services despite its fewer resources. Objective: To anticipate a brief recapitulation of the infrastructure of Rehabilitation medicine and its' services as well as demographic data and, disease pattern among the patients dealt by it in a Tertiary Hospital. Materials and Methods: This is a retrospective study executed in the department of PMR of Kurmitola General Hospital, Dhaka from January 2019 to December 2019. Results: Currently 4 Rehabilitation Physicians (Physiatrist) and 3 Physical Therapists, are involved in indoor, outdoor and, specialized PMR services with 4 indoor beds. Total thirty four thousands seven hundred thirty six (n=34,736) patients were studied who received our services, among them 35.62% were male and 64.38% were female. 16% of patients were under 20 years of age, about 61% of patients belong to 2nd, 3rd, 4th, 5th decades and 23% were above 60 years of age. Nonspecific Low Back Pain (NSLBP) were 23.80%, 8.29% Neck pain, cervical spondylosis11.15%, lumbar spondylosis 11.52%, frozen shoulder 9.83%, PLID 7.39%, osteoarthritis 9.15%, facial palsy 0.53%, rheumatoid arthritis 4.47%, seronegative spondyloarthopathy 1.26%, Guillain-Barre` Syndrome (GBS) 0.15%, planter fasciitis 4.68%, 2.10 % postsurgical/post-traumatic stiffness and others were 5.13%. Conclusion: It is time demand to build more infrastructures country wide to improve physical medicine and rehabilitation services for the country people. KYAMC Journal Vol. 11, No.-2, July 2020, Page 62-66

10.3329/kyamcj.v11i2.48416

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A Review on Applications of Nanobots in Combating Complex Diseases

Bangladesh Pharmaceutical Journal (2019)

Tashnuva Rifat Md Shahadat Hossain Md Mahbubul Alam Abu Shara Shamsur Rouf

In the current years, a lot of research works have been continued in the quest to find a desired drug delivery system within the human body. Among different drug delivery systems, nanobots have become much popular due to its capability to perform different tasks like actuating, sensing, signaling, information processing and intelligence at nanoscale dimension. A nanobot is a robotic machine that can be programmed to diagnose, monitor and treat various vital diseases. It works at cellular level with minimum side effects and thus substitute the conventional treatment procedures. The major limitations of nanobots are proper designing and manufacturing process. In spite of its expensive manufacturing set up, they are pre-eminent for medical applications, such as nanobots like respirocytes, microbivores and clottocytes have been designed to act as artificial substitutes of blood. This article describes the use of nanobots in different fields of medical science like diagnosis and treatment of cancer, diabetes, aneurysm, tetanus, HIV, skin disease, gout as well as in the field of dentistry, surgery and treating many other diseases. It also represents the recent research which has been applied in vivo to different animals. Scientists hope that nanobots will act on molecular level, protect the biological system and thus ensure a better and longer life. Bangladesh Pharmaceutical Journal 22(1): 99-108, 2019

10.3329/bpj.v22i1.40081

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Citations (18)

Understanding residents’ behaviour intention of recycling plastic waste in a densely populated megacity of emerging economy

Heliyon (2023)

Qian Jia Md. Sahidul Islam Md Shahadat Hossain Fengting Li Ying Wang

Plastic waste is choking our planet, but the recycling rate is still universally low. Understanding factors affecting recycling behaviours can help address this pressing issue. Taking Dhaka as an example, this study explores the determinants of the intentions to recycle plastic waste. We employed the Theory of Planned Behaviour (TPB) and extended it with two additional variables: Moral Norms, and Perceived sufficiency of knowledge and policy support. Survey data of 577 were collected and analysed using PLS-SEM. The findings suggest attitude, perceived behavioural control, moral norms and subjective norms significantly impact recycling intention, among which moral norms (β = 0.148, p < 0.05) acts even more strongly than subjective norms (β = 0.12, p < 0.05). Moreover, low level perception of knowledge and policy support makes people perceive less control over recycling behaviour (β = 0.188, p < 0.05), but actually reinforce their recycling intention (β = −0.091, p < 0.1). This study enriches the theoretical discussion of TPB, and contributes to the efforts of encouraging plastic recycling in populated megacity of emerging economy.

Megacity

Choking

Risk Perception

10.1016/j.heliyon.2023.e18921

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Citations (11)

Tracing the route to organisational performance through expatriate leadership effectiveness: the role of emotional, cultural and spiritual intelligence

International Journal of Business Excellence (2024)

Ahasanul Haque Naila Anwar Chowdhury Md Asadul Islam Md Shahadat Hossain Md Atiqur Sarker

Expatriate

Tracing

10.1504/ijbex.2024.141322

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Citations (1)