Raymundo Cruz

Center for Research and Advanced Studies of the National Polytechnic Institute

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Juan B. Kourí

Center for Research and Advanced Studies of the National Polytechnic Institute

Moisés Romero‐Ortega

Universidad Autónoma del Estado de México

Magdalena Miranda-Sánchez

Center for Research and Advanced Studies of the National Polytechnic Institute

Guillermo Negrón

Universidad Autónoma Metropolitana

Rubén Gaviño

Universidad Nacional Autónoma de México

Aydeé Fuentes

Universidad Autónoma del Estado de México

Yolanda Dı́az

Universidad Rovira i Virgili

B. QUICLET‐SIRE

Centre National de la Recherche Scientifique

Carlos Lavalle-Montalvo

Universidad Nacional Autónoma de México

F. García

Pontificia Universidad Javeriana

Cooperative Institutions

John Wiley & Sons (United States)

123

Bioengineering Center

119

National Center for Genetic Engineering and Biotechnology

116

Universidad Nacional Autónoma de México

Center for Research and Advanced Studies of the National Polytechnic Institute

Instituto Politécnico Nacional

Centre National de la Recherche Scientifique

Hudson Institute

Universidad Autónoma de la Ciudad de México

Universidad Autónoma del Estado de México

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ChemInform Abstract: STEREOSELECTIVE TOTAL SYNTHESIS OF (.+‐.)‐ISOCOSTIC AND (.+‐.)‐3‐OXOISOCOSTIC ACIDS

Chemischer Informationsdienst (1982)

Raymundo Cruz R. M. MARTINEZ

Abstract Das durch Robinson‐Anellierung aus Methylcyclohexanon (I) zugängliche Enon (II) wird durch allylische NBS‐Bromierung und anschließende Dehydrohalogenierung in das Dienon (III) übergeführt, das in einer stereoselektiven Michael‐Addition mit Cyanessigester bevorzugt das cis‐Addukt (IV) liefert, das durch fraktionierte Kristallisation isoliert wird.

10.1002/chin.198228301

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ChemInform Abstract: A New Synthesis of 2′,3′‐Didehydro‐3′‐deoxy‐3‐alkylthymidine.

ChemInform (1995)

Guillermo Negrón B. QUICLET‐SIRE Yolanda Dı́az Rubén Gaviño Raymundo Cruz

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199551268

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3,3',5'-Triiodo-L-Thyronine Reduces Efficiency of mRNA Knockdown by Antisense Oligodeoxynucleotides: A Study with Pyroglutamyl Aminopeptidase II in Adenohypophysis

Oligonucleotides (2004)

Raymundo Cruz Lucía Chávez‐Gutiérrez Patricia Joseph‐Bravo Jean‐Louis Charli

The impact of hormones on the efficacy of antisense oligodeoxynucleotides (ASOs) is a poorly analyzed subject. We designed, based on the identification of potentially favorable local elements of mRNA secondary structure, eight phosphorothioate ASOs to knock down the expression of an ectopeptidase, pyroglutamyl aminopeptidase II (PPII), in primary cultures of adenohypophysis. Two of the PPII ASOs were very efficient, sequence-specific, and target-specific. Because the expression of PPII is upregulated by 3,3',5'-triiodo-L-thyronine (T3), we studied the impact of varying the protocol of PPII induction on the knockdown efficacy. Hormone removal at transfection increased markedly the ability of (1) PPII ASOs to reduce PPII mRNA levels or PPII activity in adenohypophyseal cells or in C6 rat glioma cells and (2) a thyrotropin-releasing hormone (TRH) receptor-1 (TRH-R1) ASO to reduce TRH-R1 mRNA levels in adenohypophyseal cells. There was no effect of hormone removal on transfection efficacy and no correlation between target mRNA levels and ASO efficacy. These data demonstrated that ASO efficacy could depend on T3 levels; this might be due to regulation of a step generally critical for ASO efficiency.

Polyproline helix

Thyronine

10.1089/oli.2004.14.176

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Structure and function of pyroglutamyl peptidase II, the TRH inactivating enzyme

Neuropeptides (2006)

Jean-Louis Charli Lucía Chávez‐Gutiérrez Eduardo J. Matta Raymundo Cruz Milagros A. Fuentes-Vargas

10.1016/j.npep.2006.09.036

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Citations (1)

198 MORPHOFUNCTIONAL CHANGES OF CHONDROCYTES DURING OSTEOARTHRITIS ARE RELATED WITH THE EXPRESSION OF MOLECULES INVOLVED IN THE INFLAMMATORY PROCESS

Osteoarthritis and Cartilage (2008)

Mariel Rojas-Ortega Maylin Almonte‐Becerril Raymundo Cruz Elena González‐Castillo Maria Zena Miranda

Expression (computer science)

10.1016/s1063-4584(08)60244-7

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A New Synthesis of 2′,3′-Didehydro-3′-deoxy-3-Alkylthymidine

Nucleosides and Nucleotides (1995)

Guillermo Negrón B. QUICLET‐SIRE Yolanda Dı́az Rubén Gaviño Raymundo Cruz

Abstract The preparation of 3-alkyl D4T derivatives has been carried out starting from the corresponding 5′-O-t-butyldimethylsilyl-3′-O-methanesulfonylthymidine 2 by way of deprotection-elimination and succesive alkylation reactions.

10.1080/15257779508009490

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Citations (6)

Latexin expression correlated with mineralization of articular cartilage during progression of post-traumatic osteoarthritis in a rat model.

Histology and histopathology (2020)

América Martínez-Calleja Raymundo Cruz Magdalena Miranda-Sánchez Rogelio Fragoso‐Soriano M. A. Vega-López

As latexin has been linked with chondrocyte hypertrophic differentiation it is possible that this protein may also be involved in the mineralization of cartilage in OA. Therefore, we correlated latexin expression with the mineralization marker, alkaline phosphatase and determined the mineral deposition in the articular cartilage by analyzing the Ca/P ratio and the collagen fibrils pattern, during the progression of post-traumatic OA in a rat model. OA was induced by medial meniscectomy and post-surgery exercise for 5, 10, 20 and 45 days. Protein expression in articular cartilage was evaluated by immunofluorescence, histochemistry and Western blot. Minerals and structure of collagen fibrils in the superficial zone of cartilage were analyzed by energy dispersive X-ray spectroscopy (EDX) and atomic force microscopy (AFM) respectively. Protein expression analysis showed time-dependent up-regulation of latexin during OA progression. In the cartilage, latexin expression correlated with the expression and activity of alkaline phosphatase. EDX of the superficial zone of cartilage showed a Ca/P ratio closer to theoretical values for basic calcium phosphate minerals. The presence of minerals was also analyzed indirectly with AFM, as the collagen fibril pattern was less evident in the mineralized tissue. Latexin is expressed in articular cartilage from the early stages of post-traumatic OA; however, minerals were detected after latexin expression was up-regulated, indicating that its activity precedes and remains during the pathological mineralization of cartilage. Thus, our results contribute to the identification of molecules involved in the mineralization of articular chondrocytes.

10.14670/hh-18-151

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Citations (3)

Technical basis of autotransplantation of islets in the spleen: (An experimental study in dogs)

Abcd: Arquivos Brasileiros de Cirurgia Digestiva (1989)

Jaques Waisberg Joana Goncalves Raymundo Cruz Gijs W.D. Landman A Zanotto

Autotransplantation

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Citations (1)

CCDC 768383: Experimental Crystal Structure Determination

The Cambridge Structural Database (2010)

Braulio Rodríguez‐Molina Arturo Pozos Raymundo Cruz María‐Paz Romero Bienvenido Flores

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/cctskkp

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The Immediate Effects of Myofascial Release on Lumbar Range of Motion and Flexibility in Healthy Individuals: A Double-Blind, Randomized Sham-Controlled Trial

Journal of Bodywork and Movement Therapies (2025)

Mark Gugliotti Alex Rothstein Ellior Badash Raymundo Cruz Cordon Cummings

Myofascial release

Single blind

10.1016/j.jbmt.2025.01.052

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