W. Benton

Texas Woman's University

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Dayna L. Averitt

Texas Woman's University

Sirima Tongkhuya

United States Army Institute of Surgical Research

Lynda Uphouse

Texas Woman's University

Rebecca Hornung

Texas A&M University

Cierra M.C. Lopez

MIND Research Institute

J. Lee

Texas Woman's University

Phillip R. Kramer

Texas A&M University

R. Besher

Woman’s Hospital of Texas

Sukhbir Kaur

Saskatchewan Health

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Texas Woman's University

National Institutes of Health

Texas A&M University

The University of Texas at Dallas

Gaston College

Woman’s Hospital of Texas

Women's Hospital

United States Army Institute of Surgical Research

University of North Texas

National Institute of Environmental Health Sciences

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Sex Differences and Estrous Cycle Effects of Peripheral Serotonin-Evoked Rodent Pain Behaviors

Neuroscience (2018)

Sukhbir Kaur W. Benton Sirima Tongkhuya Cierra M.C. Lopez Lynda Uphouse

Rodent model

10.1016/j.neuroscience.2018.05.017

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Citations (24)

Progesterone and Allopregnanolone Rapidly Attenuate Estrogen-Associated Mechanical Allodynia in Rats with Persistent Temporomandibular Joint Inflammation

Frontiers in Integrative Neuroscience (2020)

Rebecca Hornung W. Benton Sirima Tongkhuya Lynda Uphouse Phillip R. Kramer

Temporomandibular joint disorder (TMD) is associated with pain in the joint (temporomandibular joint, TMJ) and muscles involved in mastication. TMD pain dissipates following menopause but returns in some women undergoing estrogen replacement therapy. Progesterone has both anti-inflammatory and antinociceptive properties, while estrogen's effects on nociception are variable and highly dependent on both natural hormone fluctuations and estrogen dosage during pharmacological treatments, with high doses increasing pain. Allopregnanolone, a progesterone metabolite and positive allosteric modulator of the GABA

Allopregnanolone

Allodynia

10.3389/fnint.2020.00026

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Citations (35)

(115) Protective role of progesterone against allodynia in rats with persistent temporomandibular joint inflammation

Journal of Pain (2017)

Rebecca Hornung W. Benton Sirima Tongkhuya Lynda Uphouse Dayna L. Averitt

Allodynia

10.1016/j.jpain.2017.02.021

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Citations (1)