ABSTRAK : To study drug efficiency and strain resistancy in Indonesia the drugs Suramin, Isometamedium chloride and Diminazene aceturate were tested in mice. Mice were inoculated with the fresh blood from animals infected with various T. evansi isolates and treatment was carried out 24 hours later. Suramin has been found to be an effective drug against surra at a dose rate of 5 mg/kg and there are some indications that a smaller dose is still effective. At dose rates of 3.5 to 7 mg/kg Diminazene aceturate appeared to be an effective drug for certain isolates, but was not effective against others. Isometamidium chloride at the dose rates of 0.25 to 3 mg/kg was generally ineffective.
