Shangli Zhang

Shandong University

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Jun‐Ying Miao

Shandong University

Jing Zhao

Shandong University

Bao‐Xiang Zhao

Shandong University

Le Su

Qilu University of Technology

Wenhao Gui

Beijing Jiaotong University

Yun Zhang

Chinese Academy of Medical Sciences & Peking Union Medical College

Yun Zhang

Harbin Medical University

Qitao Zhao

Shandong University of Traditional Chinese Medicine

Deling Yin

Shandong First Medical University

Xia Liu

Zhejiang University

Cooperative Institutions

Shandong University

Chinese Academy of Sciences

Shandong First Medical University

Peking University

Chinese Academy of Medical Sciences & Peking Union Medical College

Shandong Provincial Hospital

Shanghai Jiao Tong University

Ministry of Education of the People's Republic of China

Fudan University

Massachusetts General Hospital

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Influence Analysis on Ridge Estimator in General Growth Curve Model

Shangli Zhang

We discuss the influence analysis of Ridge Estimator in General Growth Curve Model,establish the relationships of Ridge Estimator among different models,give the influential measurement and its computational formal which can be assessed the disturbing influence.

Growth curve (statistics)

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The effect of two novel amino acid-coated magnetic nanoparticles on survival in vascular endothelial cells, bone marrow stromal cells, and macrophages

Nanoscale Research Letters (2014)

Qinghua Wu Ning Meng Yanru Zhang Lei Han Le Su

Magnetic nanoparticles (MNPs) have been popularly used in many fields. Recently, many kinds of MNPs are modified as new absorbents, which have attracted considerable attention and are promising to be applied in waste water. In our previous study, we synthesized two novel MNPs surface-coated with glycine or lysine, which could efficiently remove many anionic and cationic dyes under severe conditions. It should be considered that MNP residues in water may exert some side effects on human health. In the present study, we evaluated the potential nanotoxicity of MNPs in human endothelial cells, macrophages, and rat bone marrow stromal cells. The results showed that the two kinds of nanoparticles were consistently absorbed into the cell cytoplasm. The concentration of MNPs@Gly that could distinctly decrease survival was 15 μg/ml in human umbilical vascular endothelial cells (HUVECs) or bone marrow stromal cells (BMSCs) and 10 μg/ml in macrophages. While the concentration of MNPs@Lys that obviously reduced viability was 15 μg/ml in HUVECs or macrophages and 50 μg/ml in BMSCs. Furthermore, cell nucleus staining and cell integrity assay indicated that the nanoparticles induced cell apoptosis, but not necrosis even at a high concentration. Altogether, these data suggest that the amino acid-coated magnetic nanoparticles exert relatively high cytotoxicity. By contrast, lysine-coated magnetic nanoparticles are more secure than glycine-coated magnetic nanoparticles.

Viability assay

Nanotoxicology

10.1186/1556-276x-9-461

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Citations (12)

Sodium orthovanadate suppresses palmitate-induced cardiomyocyte apoptosis by regulation of the JAK2/STAT3 signaling pathway

APOPTOSIS (2016)

Jing Liu Hui Fu Fen Chang Jinlan Wang Shangli Zhang

Dephosphorylation

Lipotoxicity

Sodium orthovanadate

10.1007/s10495-016-1231-8

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Admissibility of linear estimators with respect to inequality constraints under some loss functions

Acta Mathematicae Applicatae Sinica English Series (2017)

Shangli Zhang Hong Qin Chang-Chun Wu

Matrix (chemical analysis)

TRACE (psycholinguistics)

Linear algebra

10.1007/s10255-017-0719-5

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Chloroquine inhibits cell growth and induces cell death in A549 lung cancer cells

Bioorganic & Medicinal Chemistry (2006)

Chuandong Fan Weiwei Wang Bao‐Xiang Zhao Shangli Zhang Jun‐Ying Miao

Viability assay

10.1016/j.bmc.2005.12.035

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Citations (171)

Gene polymorphisms (rs324957, rs324981) in NPSR1 are associated with increased risk of primary insomnia

Medicine (2020)

Yuping Xie Yuan Zhao Liya Zhou Lijun Zhao Jinfeng Wang

Neuropeptide S and neuropeptide S receptor (NPSR1) are associated with sleep regulation. Herein, the possible contribution of 6 polymorphisms in NPSR1 on the chromosome to primary insomnia (PI) and objective sleep phenotypes was investigated.The study included 157 patients with PI and 133 age- and sex-matched controls. All subjects were investigated by polysomnography for 3 consecutive nights. The genotyping of 6 polymorphisms was carried out by polymerase chain reaction-restriction fragment length polymorphism method.A significant difference was detected for rs324957 and rs324981 between PI and controls. The PI patients had a higher frequency of AA than controls in rs324957 (P = .02) and rs324981 (P = .04). However, for other single nucleotide polymorphisms (rs323922, rs324377, rs324396, and rs324987), no significant differences were observed between PI patients and controls. There were 2 different allelic combinations that were associated with PI susceptibility (CATGTC, GCCAAT) and its risk factor. A significant difference in sleep latency was observed among 3 genotype carriers of NPSR1 gene polymorphism rs324957 in PI group (P = .04), with carriers of the A/A genotype having the longest sleep latency (mean ± SD: 114.80 ± 58.27), followed by the A/G genotype (112.77 ± 46.54) and the G/G genotype (92.12 ± 42.72).This study provided the evidence that the NPSR1 gene polymorphisms (rs324957, rs324981) might be susceptibility loci for PI. Further studies are needed to explore the role of NPSR1 gene polymorphisms in molecular mechanisms of PI in a larger sample size.

10.1097/md.0000000000021598

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Citations (3)

Cooperation of phosphatidylcholine-specific phospholipase C and basic fibroblast growth factor in the neural differentiation of mesenchymal stem cells in vitro

The International Journal of Biochemistry & Cell Biology (2007)

Nan Wang Chunhui Sun Si-Wei Huo Yun Zhang Jing Zhao

10.1016/j.biocel.2007.08.003

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Citations (33)

Cross-entropy minimization estimation for two-phase sampling and non-response

Journal of Systems Science and Complexity (2015)

Chang-Chun Wu Linjun Tang Shangli Zhang