Steven Tringali

California State University, Fresno

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Tushar Acharya

National Heart Lung and Blood Institute

G Catenacci

University of Pavia

Jian Huang

Medtronic (United States)

Giovanni Paolo Pollini

Azienda Ospedaliera Universitaria Integrata Verona

G Pezzagno

Fondazione Salvatore Maugeri

U Maugeri

Fondazione Salvatore Maugeri

Manminder Bhullar

University of California, San Francisco

Dino Dukovic

California Miramar University

Ishak A. Mansi

University of Central Florida

Prakash Deedwania

University of California, San Francisco

Cooperative Institutions

University of California, San Francisco

California State University, Fresno

University of Arizona

Dayanand Medical College & Hospital

Liver Institute Northwest

Punjab Institute of Medical Sciences

Icahn School of Medicine at Mount Sinai

VA Central California Health Care System

Ross University School of Medicine

Ark Medical Center

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Seasonal Variations of Hospital Admissions for Alcohol-Related Hepatitis in the United States

Gastroenterology Research (2022)

Aalam Sohal Kanwal Bains Armaan Dhaliwal Hunza Chaudhry Raghav Sharma

Background: Clinical experience suggests an increased hospitalization rate for alcohol-related hepatitis (AH) in the winter months; however, seasonal variations in the prevalence of hospitalizations for AH have not been described previously. We hypothesized that AH hospitalizations would be higher in the winter months due to the holiday season and increased alcohol sales. Methods: Patients with primary or secondary discharge diagnoses of AH were included in the study (International Classification of Diseases, Clinical Modification-10th Revision codes K70.4 and K70.1) between January 2016 and December 2019. The primary outcome measure for this study was daily hospitalizations by each month of the year. Secondary outcome measures included the rate of in-hospital mortality associated with AH, hospital length of stay, and total hospitalization cost for each month. Results: The highest number of AH-related admissions was reported in July (n = 56,800; 9%), followed by August (n = 55,700; 8.8%) and May (n = 54,865; 8.7%). February had the lowest number of admissions (n = 46,550; 7.37%). The adjusted mortality was highest in December (overall mortality: 9.6%; adjusted odds ratio: 1.29; 95% confidence interval: 1.142 - 1.461; P < 0.0001) and lowest in May (overall mortality rate: 7.7%). No difference was noted between length of stay and total hospitalization cost between months. Conclusion: Our findings demonstrate that seasonal variations in hospitalizations related to AH do exist across the United States. Regional differences also exist and follow unique patterns. The increase in admissions for AH is in line with other studies suggesting that heavy drinking happens during the warm season. Hospital administrators and other stewards of healthcare resources can use seasonal patterns to guide allocation of resources. Gastroenterol Res. 2022;15(2):75-81 doi: https://doi.org/10.14740/gr1506

10.14740/gr1506

Cite

Citations (1)

[The biological monitoring of those exposed to 1,1,1-trichloroethane: a longitudinal study].

PubMed (1991)

G Catenacci G Pezzagno Steven Tringali R Terzi L Fidanza

Data on long-term biological monitoring in two groups of workers engaged in cleaning operations in a wool factory and exposed to methylchloroform are presented. The longitudinal survey lasted one year and brought about 19 random systematic sampling (once or twice a month for everyone of the 13 subjects monitored). The biological marker adopted was the urinary concentration of the solvent as such, according to a previously studied method. The collected data allowed to measure: the annual average level of exposure (estimated by the long term geometric mean); the day to day variation of the true daily exposure averages (estimated by the geometric standard deviation); the probability of overexposure (daily exposures exceeding the biological exposure limit) and the yearly number of work shifts of overexposure. The usefulness of performing long-term surveys of occupational exposure to the chemical substances by mean of longitudinal biological monitoring is discussed.

Geometric standard deviation

Source

Cite

Citations (0)

Reduction of diastolic blood pressure: Should hypertension guidelines include a lower threshold target?

World Journal of Hypertension (2017)

Steven Tringali Jian Huang

Reduction of diastolic blood pressure: Should hypertension guidelines include a lower threshold target?

10.5494/wjh.v7.i1.1

Cite

Citations (3)

Low Diastolic Blood Pressure as a Risk for All-Cause Mortality in VA Patients

International Journal of Hypertension (2013)

Steven Tringali Charles William Oberer Jian Huang

Background. A paradoxical increase in cardiovascular events has been reported with intensively lowering diastolic blood pressure (DBP). This J-curve phenomenon has challenged the aggressive lowering of blood pressure, especially in patients with coronary artery disease. Objective. Our objective was to study the effects of low DBP on mortality and determine a threshold for which DBP should not be lowered beyond. Methods. We evaluated a two-year cross-section of primary care veteran patients, from 45 to 85 years of age. Receiver operating characteristics (ROC) were employed to establish an optimal cut-off point for DBP. Propensity-score matching and multivariate logistic regression were used to control for confounders. All-cause mortality was the primary outcome. Results. 14,270 patients were studied. An ROC curve found a threshold value of DBP 70 mmHg had the greatest association with mortality (P < 0.001). 49% of patients had a DBP of 70 mmHg or less. Using a propensity-matched multivariate logistic regression, odds ratio for all-cause mortality in subjects with a DBP less than 70 mmHg was 1.5 (95% CI 1.3-1.8). Conclusions. Reduction of DBP below 70 mmHg is associated with increased all-cause mortality. Hypertension guidelines should include a minimum blood pressure target.

10.1155/2013/178780

Cite

Citations (29)

[Decrement of respiratory function indices in a case series of workers exposed to cement dust: a longitudinal study].

PubMed (1988)

G Catenacci Steven Tringali Giuseppe Brunetti G Pezzagno

Longitudinal changes in some respiratory parameters (FEV1 and VC) have been examined in a sample of cement workers (163 male subjects differently exposed to cement dusts); the subjects have been surveyed over a period of 10 years performing yearly spirometric tests (Vital capacity--VC and Forced Expiratory Volume in 1 second--FEV1 measurements). Three possible risk indicators have been considered: occupational exposure, smoking habit and age. 65.6% and 60.7% of the cases showed significant individual annual decreases of VC and FEV1 throughout the time of follow up. According to our results the occupational risk indicator has not significantly influenced the normal trend of decreases of the respiratory parameters; instead age brings about an increase of longitudinal changes of VC and smoke habit an increase of longitudinal changes of FEV1, (but only in the younger group, people less than forty years old). 16 subjects characterized by abnormal losses (more than 100 ml/year) have been selected as "VC-FEV1, losers".

Longitudinal Study

Habit

Vital capacity

Source

Cite

Citations (2)

Statin Use and the Risk of Kidney Disease With Long-Term Follow-Up (8.4-Year Study)

The American Journal of Cardiology (2015)

Tushar Acharya Jian Huang Steven Tringali Christopher R. Frei Eric M. Mortensen

10.1016/j.amjcard.2015.11.031

Cite

Citations (40)

Resistant Hypertension and Associated Comorbidities in a Veterans Affairs Population

Journal of Clinical Hypertension (2014)

Tushar Acharya Steven Tringali Manmeet Mahinderjit Singh Jian Huang

Resistant hypertension ( RH ) is understudied and its reported prevalence varies with study populations. The authors sought to determine its prevalence and association with certain comorbid conditions in a Veterans Affairs population. This cross‐sectional study utilized demographic and clinical data from 17,466 patients. Chi‐square or t test was used for comparing groups with and without RH . Multivariate logistic regression analysis was used to determine independent associations. Overall, the prevalence of RH was 9%, and 13% of all hypertensive patients met criteria for RH. After adjusting for confounding variables, RH was significantly associated with older age (odds ratio [ OR], 1.007), higher body mass index ( OR, 1.04), Framingham score ( OR, 1.14), and coexisting coronary artery disease , cerebrovascular accident / transient ischemic attack , peripheral vascular disease , congestive heart failure , chronic kidney disease , diabetes mellitus , erectile dysfunction, and metabolic syndrome ( OR, 1.3, 1.32, 1.29, 2.88, 2.13, 1.2, 1.12, and 1.2, respectively; all P <.05). Our results indicate a complex interplay of certain comorbid conditions among patients with RH and suggest the need for multifaceted interventions in this high‐risk population to prevent cardiovascular events.

Veterans Affairs

10.1111/jch.12410

Cite

Citations (36)

Serum lipids and lipoproteins in relation to smoking among the apparently healthy workers: a preliminary survey. The Pavia Study.

PubMed (1985)

Giovanni Paolo Pollini U Maugeri Steven Tringali W Jedrychowski

This pilot study is concerned mainly with the interrelationships between serum lipids and lipoproteins, and personal variables like age, body mass index (BMI) and smoking habit. The analysis was limited to the male workers employed in the Lombardia region. The results of the study confirm the findings of the other investigators on the interaction between smoking and lipid metabolism. The effect of smoking on the cholesterol level appeared to have been the most pronounced and the clear strong relationship with the exposure was established. Also triglycerides concentration was related to the smoking exposure. The HDL lipoproteins were lower and LDL-VLDL higher in smokers than in nonsmokers, however, the association with the smoking exposure was insignificant. The findings showed that HDL-cholesterol level was inversely dependent on the plasma triglycerides both in nonsmokers and smokers. The paper discusses the implications of the research carried out on the interpretation of the HDL-cholesterol values as a eventual potential risk factor for the coronary heart disease.

Source

Cite

Citations (1)

A Single Controlled Exposure to Secondhand Smoke May Not Alter Thrombogenesis or Trigger Platelet Activation

Nicotine & Tobacco Research (2015)

Sundararajan Srikanth Fridolin Sy Kamal Kotak Richard Kiel Muhammad Bajwa

Chronic secondhand smoke (SHS) exposure increases cardiovascular events, particularly acute thrombotic events. There are little human data on acute SHS exposure. The aim of this study was to determine whether a single controlled exposure of humans to SHS increased thrombogenesis. After 6–8 hours fast, subjects ( n = 50) were exposed to constant dose SHS (particulate level of 500 μg/m 3 ) for 120 minutes in a temperature-regulated and ventilated, simulated bar environment. Blood was drawn before and immediately after SHS exposure for thromboelastography (TEG) and flow cytometry. Maximum clot strength (MA) was measured using TEG and platelet leukocyte aggregates (LPA) were measured as an index of platelet activation. Anti-CD 14 antibodies were used as leukocyte markers and anti-CD 41 antibodies as platelet markers for cytometry. Data were analyzed using students' t test for paired samples. There was no effect of acute exposure to SHS on platelet activation or thrombogenesis. Also, intra group (smokers [ n = 19] and nonsmokers [ n = 31]) comparisons of LPA and TEG parameters did not show changes with SHS exposure. While there are abundant data showing enhanced thrombogenesis and platelet activation following repeated exposure to SHS, our study suggests that a single exposure does not appear to significantly alter thrombin kinetics nor result in platelet activation. The effects of SHS on thrombogenesis might be nonlinear.

Secondhand Smoke

10.1093/ntr/ntv133

Cite

Citations (5)

[Retrospective study of morbidity in a group professionally exposed to chlorotriazine herbicides].

PubMed (1997)

G Catenacci Steven Tringali Rabia Terzi

Two different groups of workers involved, during the last 10 years, in the production or formulation of chlorotriazine herbicides have been retrospectively studied in order to verify the occurrence of diseases possibly related to Atrazine, Simazine, Propazine and Terbuthylazine exposure. A control group has been selected between clerical workers of the same plants. Exposure data have been collected during the last five years and some extrapolations have been performed to hypothesize the level of exposure in the preceeding years. Clinical findings and laboratory data obtained from ten year medical surveillance records have been evaluated to highlight possible differences between the investigated groups. A first close examination of the data concerning the anamnesis and clinical, hematochemical and functional reports of the three groups of investigated subjects does not show any pathological situation or symptoms specifically connected to chlorotriazine compounds exposure and/or significant differences between exposed and non exposed. A next series of statistical surveys involving some of the hematochemical indicators (RBC, WBC, Hb%, SGOT, SGPT, gamma GT) has been performed either on internal values of each group or on the average-values of the three groups differently exposed (production, formulation, control). The first survey was a longitudinal study, the second one was a cross sectional one. Both the investigations have excluded significant differences attributable to the occupational exposure.

Simazine

Source

Cite

Citations (1)