Linda L. Hernández

The effects of intraseptal scopolamine hydrobromide injections on Pavlovian (classical) conditioning were evaluated, with tones used as the conditioned stimulus (CS) and a periorbital electric shock train as the unconditioned stimulus (UCS). Eye blink (EB) and heart rate (HR) conditioned responses were concomitantly recorded. Although injections of scopolamine into the medial septum impaired the acquisition of the Pavlovian conditioned eyelid reflex, these injections enhanced the magnitude of accompanying Pavlovian conditioned HR decelerations. However, scopolamine applied to the lateral septal area had no effect on EB conditioning, relative to the vehicle, but, like medial injections, enhanced the magnitude of the accompanying HR decelerations. These results are compatible with those of previous investigations: Medial septal dysfunction impairs somatomotor conditioning but leaves autonomic conditioning intact, and septal dysfunction produces a parasympathetic bias of the cardiovascular system.

Scopolamine Hydrobromide

Stimulus (psychology)

10.1037/0735-7044.99.1.75

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Citations (21)

Intraseptal scopolamine has differential effects on Pavlovian eye blink and heart rate conditioning.

Behavioral Neuroscience (1985)

D. A. Powell Linda L. Hernández Shirley L. Buchanan

Scopolamine

10.1037//0735-7044.99.1.75

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Citations (1)

Ethanol enhancement of Pavlovian conditioning.

Behavioral Neuroscience (1986)

Linda L. Hernández James D. Valentine D. A. Powell

10.1037/0735-7044.100.4.494

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Citations (20)

Effects of opiates on the discriminative stimulus properties of dopamine agonists

Pharmacology Biochemistry and Behavior (1978)

Linda L. Hernández Alice M. Holohean James B. Appel

Apomorphine

Pentazocine

Stimulus generalization

Opiate

Stimulus (psychology)

10.1016/0091-3057(78)90041-2

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Citations (20)

Experimental Aging Research (1981)

D. A. Powell S.L. Buchanan Linda L. Hernández

Abstract Two groups of New Zealand albino rabbits of approximately six and forty months of age respectively were subjected to Pavlovian conditioning in which a 1216 Hz, 75 dB tone served as the conditioning stimulus and a brief paraorbital electric shock train served as the unconditioned stimulus. Eyeblink and heart rate responses were assessed. Older animals revealed acquisition deficits in the somatomotor eyelid conditioning task compared to the young animals: however, the magnitude of the concomitantly occurring heart rate change was greater in older than in younger animals. These age-related changes appeared to be enhanced in males and were unrelated to general activity differences, or to the un- conditioned response to unpaired tones or electric shocks.

Stimulus (psychology)

Conditioned response

Eyeblink conditioning

10.1080/03610738108259824

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Citations (66)

Dopaminergic involvement in the mechanism of action of pentazocine

Behavioral and Neural Biology (1979)

Linda L. Hernández James B. Appel

Pentazocine

Neurochemical

Opiate