Apolipoprotein AIV (apo AIV) and cholecystokinin (CCK) are peptides that act both peripherally and centrally to reduce food intake by decreasing meal size. The present study examined the effects of intraperitoneally administered bolus doses of recombinant apo AIV, CCK-8, and a combination of subthreshold doses of apo AIV and CCK on 4-h food intake in rats that were fasted overnight. Apo AIV at 100 microg/kg reduced food intake significantly relative to the saline control for 1 h, as did doses of CCK-8 at or above 0.125 microg/kg. Doses of apo AIV (50 microg/kg) or CCK (0.06 microg/kg) alone had no effect on food intake. However, when these subthreshold doses of apo AIV and CCK were administered together, the combination produced a significant inhibition of food intake relative to saline controls (P < 0.001), and the duration of the effect was longer than that caused by the administration of either apo AIV or CCK alone. The satiation effect produced by CCK-8 + apo AIV was attenuated by lorglumide, a CCK1 receptor antagonist. We conclude that, whereas the intraperitoneal administration of doses of either recombinant apo AIV or CCK at or above threshold levels reduces food intake, the coadministration of subthreshold doses of the two peptides is highly satiating and works via CCK1 receptor.

Weanling

10.1152/ajpregu.00329.2007

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Application of Audio Education in Respiratory Medicine Wards

Clinical Nursing Research (2019)

Zhao Yong-mei Min Liu Zhihong Fan Jinjing Li Ling Shi

Improving the efficiency of patient education can help improve patient's satisfaction and alleviate the pressure of nurse shortage. This study aimed to develop and pilot an educational audio to improve the effectiveness of inpatient education. A primary literature review was conducted and educational materials were written and recorded by MP3. A pilot study was conducted in 713 adult patients in the department of respiratory medicine at a large urban Shanghai teaching hospital. Patients in the experimental group showed greater satisfaction with their health education. For the education to be effective during the admission, the asthma patients in the experimental group spent less time in face-to-face communication. The feedback rate for disease education among asthma patients in the experimental group was significantly higher. Wider applications of audio in patient education may be valuable to better adjust to nurse reduction and to improve nursing service quality.

Respiratory Medicine

10.1177/1054773819829622

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Nursing after pneumonectomy

Min Liu

Objective To explore the nursing experience after pulmonary resection.Methods Application of nursing procedure in patient with the implementation of a comprehensive approach to holistic nursing care.Results Application of the implementation of holistic nursing care in 8 cases,2 cases of postoperative arrhythmia,the remaining 6 cases without any complications,the mean hospital stay was 20 days,cured and discharged.Conclusion Patients and their families to pneumonectomy accept degree to rise,reduce postoperative complications and improve patients' quality of life.

Holistic nursing

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Experience Crystallization of Professor Bai Zhengping on Treating Cough

Min Liu

According to reviewing the experience of Professor Bai Zhengping on treating cough by Traditional Chinese Medicine,this paper states the deep insights of Professor Bai Zhengping on cause of disease,Mechanism of disease,classification and therapy about cough as well as the characteristic of clinical treatment.The experience in this paper is effective in guiding the therapy.

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Lung cancer in patients with and without rheumatoid arthritis: A propensity score‐matched survival analysis cohort study

Thoracic Cancer (2020)

Lei Zhang Qiliang Zhao Fan Yuan Min Liu

Background Connective tissue disease increases the risk of lung cancer, but whether rheumatoid arthritis (RA) has an effect on the overall survival (OS) rate in this population has not been well studied. Methods Patients diagnosed with lung cancer between January 2015 and December 2017 were enrolled in this retrospective analysis. Propensity score matching was performed to balance the baseline of the two groups, whereas the differences between patients with and without RA were compared using survival analysis. Further, the effects of interstitial lung disease (ILD) and qi deficiency on survival in cases of RA with lung cancer were examined. Cox regression analysis was applied to predict the factors that influenced the survival of lung cancer to one year. Results Overall, 154 lung cancer patients, including 136 (88.3%) without RA and 18 (11.7%) with RA, were included. Two comparison cohorts were matched by 1:2 propensity score matching, which yielded 18 lung cancer patients with RA and 36 lung cancer patients without RA. Ultimately, the survival prognosis of lung cancer and RA was worse than that without RA, that of patients with ILD with RA and lung cancer was worse than that among those without RA, and that of patients with qi deficiency with RA and lung cancer was worse than that among those without RA. Conclusions The survival prognosis of lung cancer patients with RA is worse than that of those without RA. ILD and qi deficiency promote reduced survival when found in conjunction with RA in patients with lung cancer.

10.1111/1759-7714.13388

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Study on Inner Drainage System Design of Top Grade Highways Bituminous Pavement

Value Engineering (2010)

Min Liu

依据公路排水现状和排水设施布设情况的分析表明,高等级公路路面在使用一段时间后,不可避免地要出现各种病害,其中水是危害公路的主要自然因素.大多数路基沉陷、冲刷、坍塌,翻浆,沥青路面松散、剥落、龟裂,水泥混凝土路面唧泥、错台、断裂等病害,都不同程度地与地表水和地下水的侵蚀有关.水的作用加剧了路基和路面结构的损坏,加快了路面使用性能的恶化,缩短了它们的使用寿命.因此,道路排水是否通畅是影响路面使用性能和...

Asphalt pavement

Drainage system (geomorphology)

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Research on Corrosion Mechanism and Anti-Corrosion Measures for Antennas Exposed to Ocean Environment

Journal of Spacecraft TT&C Technology (2012)

Min Liu

Corrosion of TTC antennas exposed to ocean environment could result in performance deterioration and failure of a ground TTC station.Following analysis of the corrosion mechanism and factors of influence and imperilment,the paper presents anti-corrosion measures for TTC antennas.Beneficial guiding principles and design methods,e.g.,use of corrosion-resistant materials,isolated environment and surface protection are recommended.The feasibility of two ways of protection,i.e.,slather PVDF dope protection and sacrificial anode protection,are analyzed and details of implementation are given.

Failure mechanism

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Treatment based on differentiation of cold-heat complication syndrome with six-meridian theory in Treatise on Cold Pathogenic Disease.

Zhonghua zhongyiyao zazhi (2009)

Min Liu Yingfeng Liu

Based on the viewpoint of six meridians separately varying with the pathogenesis of exterior-interior and cold-heat,which is separately dominated by different meridians,this article systematically analyzes and generalizes the connotation of the treatment based on differentiation of various syndromes of cold-heat complication involved in Treatise on Cold Pathogenic Diseases.By delimiting which meridian the cold-heat complication syndrome belong to in six meridians and what the pathogenesis is,the article further promotes the signifi cance of six-meridian theory guiding the treatment based on differentiation of miscellaneous diseases.

Meridian (astronomy)

Pathogenesis

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Deficiency of apoA-IV in Female 129X1/SvJ Mice Leads to Diet-Induced Obesity, Insulin Resistance, and Decreased Energy Expenditure

Nutrients (2023)

Jie Qu Dong Wu Chih‐Wei Ko Qi Zhu Min Liu

Obesity is one of the main risk factors for cardiovascular diseases, type II diabetes, hypertension, and certain cancers. Obesity in women at the reproductive stage adversely affects contraception, fertility, maternal well-being, and the health of their offspring. Being a major protein component in chylomicrons and high-density lipoproteins, apolipoprotein A-IV (apoA-IV) is involved in lipid metabolism, food intake, glucose homeostasis, prevention against atherosclerosis, and platelet aggregation. The goal of the present study is to determine the impact of apoA-IV deficiency on metabolic functions in 129X1/SvJ female mouse strain. After chronic high-fat diet feeding, apoA-IV−/− mice gained more weight with a higher fat percentage than wild-type (WT) mice, as determined by measuring their body composition. Increased adiposity and adipose cell size were also observed with a microscope, particularly in periovarian fat pads. Based on plasma lipid and adipokine assays, we found that obesity in apoA-IV−/− mice was not associated with hyperlipidemia but with higher leptin levels. Compared to WT mice, apoA-IV deficiency displayed glucose intolerance and elevated insulin levels, according to the data of the glucose tolerance test, and increased HOMA-IR values at fasting, suggesting possible insulin resistance. Lastly, we found obesity in apoA-IV−/− mice resulting from reduced energy expenditure but not food intake. Together, we established a novel and excellent female mouse model for future mechanistic study of obesity and its associated comorbidities.

10.3390/nu15214655

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