D. V. Gokhale

National Chemical Laboratory

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K. B. Bastawde

National Chemical Laboratory

Mukund Adsul

Sardar Patel Renewable Energy Research Institute

Mamata Singhvi

Chungbuk National University

A.J. Varma

Armed Forces Medical College

U. S. Puntambekar

National Chemical Laboratory

S. G. Patil

National Chemical Laboratory

Meera Christopher

National Institute for Interdisciplinary Science and Technology

Rajeev K. Sukumaran

National Institute for Interdisciplinary Science and Technology

Dileep N. Deobagkar

Savitribai Phule Pune University

AthiraRaj Sreeja-Raju

National Institute for Interdisciplinary Science and Technology

Cooperative Institutions

National Chemical Laboratory

University of California, Riverside

Savitribai Phule Pune University

Academy of Scientific and Innovative Research

University of California, Berkeley

National Institute for Interdisciplinary Science and Technology

University of Wisconsin–Madison

University of California System

Iowa State University

University of Michigan–Ann Arbor

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Lignocellulose processing: a current challenge

RSC Advances (2014)

Mamata Singhvi Shivani Chaudhari D. V. Gokhale

Lignocellulosic biomass, of which inedible crops are a renewable source, is expected to become one of the key renewable energy resources in the near future, to deal with global warming and the depletion of conventional fossil fuel resources. It also holds the key to supplying society's basic needs for the sustainable production of chemicals and fuels without impacting the human food supply. Despite this, the production of 2nd generation biofuels and chemicals has not yet been commercialized. Therefore, the challenges involved in the production of lignocellulosic biomass derived fuels and chemicals must be addressed. The search for economic pretreatment methods has been recognized as one of the main hurdles for the processing of biomass to biofuels and chemicals. The conversion of all biomass components, lignin in particular, would greatly contribute to the economic viability of biomass based processes for 2nd generation biofuels and chemicals. The highly organized crystalline structure of cellulose presents an obstacle to its hydrolysis. Hydrolysis of lignocellulose carbohydrates into fermentable sugars requires a number of different biomass degrading enzymes such as cellulases and hemicellulases. Still, a number of technical and scientific issues within pretreatment and hydrolysis remain to be solved. Depending on the raw material and pretreatment technology, the enzyme mixtures must be designed to degrade biomass carbohydrates. Rapid advances in enzyme, microbial and plant engineering would provide the necessary breakthroughs for the successful commercialization of biomass derived fuels and chemicals.

Lignocellulosic Biomass

Renewable resource

Enzymatic Hydrolysis

10.1039/c3ra46112b

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Citations (109)

A Class of Alternatives to Independence in Contingency Tables

Journal of the American Statistical Association (1978)

D. V. Gokhale Nicole Johnson

Abstract A class of alternative hypotheses to independence is proposed for two-way contingency tables. It is assumed that a certain proportion of the cell probabilities under independence has been removed from (or put into) each of a subset of cells and redistributed over (or taken from) the remaining cells, keeping the marginals unchanged. The redistribution or depletion is not necessarily restricted to neighboring cells. The proposed alternatives can be expressed in log-linear form amenable to usual methods of analyses. Two numerical examples are given. Some generalizations for two-way and multi-way tables are discussed. Key Words: Contingency tablesLog-linear modelsSpecified alternative hypothesisAlternative hypothesisTest of independence

Contingency table

Independence

Contingency

10.1080/01621459.1978.10480102

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Citations (8)

INFORMATION THEORETIC METHODS FOR CATEGORICAL DATA

Advances in econometrics (1997)

Ehsan S. Soofi D. V. Gokhale

Categorical variable

10.1108/s0731-9053(1997)0000012006

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Citations (7)

Lorenz order with common finite support

METRON (2016)

Barry C. Arnold D. V. Gokhale

Lorenz curve

Identification

Finite set

10.1007/s40300-016-0101-z

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Citations (3)

Lignin–carbohydrate complexes from sugarcane bagasse: Preparation, purification, and characterization

Carbohydrate Polymers (2005)

Rishabh Singh Sandip K. Singh K.D. Trimukhe Kiran Pandare Kulbhushan B. Bastawade

Bagasse

10.1016/j.carbpol.2005.07.011

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Citations (143)

Isolation of intergeneric hybrids between Bacillus subtilis and Zymomonas mobilis and the production of thermostable amylase by hybrids.

PubMed (1994)

D. V. Gokhale Dileep N. Deobagkar

Stable hybrids were obtained by protoplast fusion between Bacillus subtilis and Zymomonas mobilis. All the hybrids were able to hydrolyse starch and possessed ampicillin- and tetracycline-resistant phenotypes. Two of the hybrids, BZ-1 and BZ-2, were hyperproducers of alpha-amylase. The enzyme produced by these hybrids exhibited increased thermostability. The results show that stable intergeneric gene transfer can be achieved through poly(ethylene glycol)-mediated protoplast fusion between two industrially important genera of bacteria.

Zymomonas mobilis

Protoplast

Thermostability

Bacillaceae

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Citations (4)

Estimation and Tests for Departures from Rao‐Structured Covariance Matrices

Biometrical Journal (1987)

Subir Ghosh D. V. Gokhale

Abstract For linear models, a measure of departure of a variance‐covariance matrix from Rao‐structure (Rao, 1967) is proposed. Relevant estimation and testing problems are discussed. Illustrative examples are also presented.

10.1002/bimj.4710290304

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Meet Our Associate Editor

Recent Patents on Biotechnology (2019)

D. V. Gokhale

10.2174/187220831302190329092506

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A Class of Alternatives to Independence in Contingency Tables

Journal of the American Statistical Association (1978)

D. V. Gokhale Nicole Johnson

Contingency table

Independence

Contingency

Redistribution

10.2307/2286283

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Citations (1)

Production of Lactic Acid from Cellobiose and Cellotriose by Lactobacillus delbrueckii Mutant Uc-3

Applied and Environmental Microbiology (2007)

Mukund Adsul J. M. Khire K. B. Bastawde D. V. Gokhale

Lactobacillus delbrueckii mutant Uc-3 utilizes both cellobiose and cellotriose efficiently, converting it into L(+) lactic acid. The enzyme activities of cellobiose and cellotriose utilization were determined for cell extracts, whole cells, and disrupted cells. Aryl-beta-glucosidase activity was detected only for whole cells and disrupted cells, suggesting that these activities are cell bound. The mutant produced 90 g/liter of lactic acid from 100 g/liter of cellobiose with 2.25 g/liter/h productivity.

10.1128/aem.00774-07

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Citations (69)