Chenyu Wu

Shanghai University of Medicine and Health Sciences

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Shuo Shi

Beijing Jiaotong University

Xuemai Gu

Harbin Institute of Technology

Yuanwei Liu

Queen Mary University of London

Changsheng You

Southern University of Science and Technology

Jian Wu

China Agricultural University

Mingfang Yi

China Agricultural University

Shanshan Seng

China Agricultural University

Benhe Gong

China Agricultural University

Junna He

China Agricultural University

Xiuzhen Wang

Nankai University

Cooperative Institutions

National Cheng Kung University

Harbin Institute of Technology

National Cheng Kung University Hospital

Chinese Academy of Sciences

China Agricultural University

Northwest A&F University

Sun Yat-sen University

Huazhong University of Science and Technology

I-Shou University

University of Electronic Science and Technology of China

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AB031. Management of congenital cystic adenomatoid malformation in newborns

Journal of Thoracic Disease (2017)

Chenyu Wu Chao‐Chun Chang Yi‐Ting Yen Yau‐Lin Tseng

Congenital cystic adenomatoid malformations (CCAM), also known as congenital pulmonary airway malformation, is a developmental defect of the respiratory tract, with unknown etiology. It is a rare disease, with an incidence of 1 in 8,300 to 1 in 35,000 but also the most common congenital lung anomaly. We present a newborn boy, GA 31+6 weeks, who was diagnosed with left CCAM at GA 20+ weeks. We did echo-guide pig-tail insertion for decompression soon after delivery, and we arranged posterolateral thoracotomy left lower lobe lobectomy 4 days later when vital sign stabilized. His post-operative course was smooth and final pathology report showed type II CCAM.

10.21037/jtd.2017.s031

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Near-Field Beam Management for Extremely Large-Scale Array Communications

arXiv (Cornell University) (2023)

Changsheng You Yunpu Zhang Chenyu Wu Yong Zeng Beixiong Zheng

Extremely large-scale arrays (XL-arrays) have emerged as a promising technology to achieve super-high spectral efficiency and spatial resolution in future wireless systems. The large aperture of XL-arrays means that spherical rather than planar wavefronts must be considered, and a paradigm shift from far-field to near-field communications is necessary. Unlike existing works that have mainly considered far-field beam management, we study the new near-field beam management for XL-arrays. We first provide an overview of near-field communications and introduce various applications of XL-arrays in both outdoor and indoor scenarios. Then, three typical near-field beam management methods for XL-arrays are discussed: near-field beam training, beam tracking, and beam scheduling. We point out their main design issues and propose promising solutions to address them. Moreover, other important directions in near-field communications are also highlighted to motivate future research.

Aperture (computer memory)

10.48550/arxiv.2306.16206

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Citations (13)

Amelioration of collagen-induced arthritis in mice by lentivirus-mediated microRNA-223 silencing

Human Gene Therapy (2011)

Chenyu Wu Y. T. Li S. Y. Chen C. R. Wang Ai‐Li Shiau

Collagen-induced arthritis

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Novel Variations in the KDM5C Gene Causing X-Linked Intellectual Disability

Neurology Genetics (2021)

Po‐Ming Wu Wenhao Yu Chi‐Wu Chiang Chenyu Wu Jia‐Shing Chen

To investigate the pathogenicity of 2 novel KDM5C variations, report the clinical and neuroimaging findings, and review the available literature.Physical examinations, structural neuroimaging studies, and exome sequence analysis were performed. KDM5C constructs were used to study the effect of the variations in transfected cells.We identified 2 novel variations c.2233C>G and c.3392_3393delAG in the KDM5C gene harboring from 2 Chinese families with X-linked intellectual disability (ID). The affected male patients exhibited severe ID, short stature, and facial dysmorphism. The 1 with c.3392_3393delAG additionally had epilepsy and autistic spectrum disorder (ASD). Transiently transfected mutant KDM5C constructs both reduced protein expression and stability and decreased histone demethylase activities in cells. Reviewing the available literature, we found that the associated ASD tended to occur in patients with variations near the C-terminus of KDM5C.We report the clinical, molecular genetic, and pathologic features in patients with novel variations of KDM5C. The variability of the clinical phenotype in addition to an ID may associate with altered particular parts of KDM5C.

10.1212/nxg.0000000000000646

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Citations (10)

DDFS design using the equi-section division method for SDR transceiver

Shiann‐Shiun Jeng Hsing-Chen Lin Chenyu Wu

In this paper, the equi-section division method utilizing the symmetry property and amplitude approximation of a sinusoidal waveform to design a direct digital frequency synthesizer (DDFS) is proposed. Here, the sinusoidal phase of a one-quarter period is divided into equi-sections. The error value between each line segment value and the sinusoidal amplitude value is saved in a ROM to reconstruct the real sinusoidal waveform. As a result, the total compression ratio of the DDFS using the equi-section division method is superior to that of the DDFS using the basic look up table (LUT). The simulation and experimental results show that the proposed method can compress the size of the ROM effectively without affecting the spectrum performance. Therefore, the new ROM compression method can be used to generate a sinusoidal waveform, and then be applied to the software defined radio (SDR) system to complete the modulation, demodulation, upconversion, and downconversion.

Direct digital synthesizer

Photon Upconversion

10.1109/pimrc.2008.4699640

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Synergic anti-tumor effect of pterostilbene, an inhibitor of type I insulin-like growth factor receptor, and trastuzumab against HER2-overexpressing bladder cancer cells

輔仁醫學期刊 (2017)

Chung-Hsien Chen Chenyu Wu Yu‐Chi Chen Tzong‐Der Way Victor C. Lin

背景及目的：二苯乙烯（stilbene）在各面都被廣泛的研究，包括對抗惡性腫瘤的能力。此研究希望證明紫檀芪（pterostilbene），一個強力的二苯乙烯，可做為新一代類胰島素生長因子1受體抑制劑並且對於膀胱癌細胞有毒殺的加乘作用。方法：我們使用紫檀芪治療膀胱癌細胞，並且利用西方墨點法分析細胞增殖試驗以及利用流式細胞技術分析癌細胞之增生及細胞週期。我們分析紫檀芪在類胰島素生長因子1受體膀胱癌的細胞並嘗試找尋下游路徑。周塔氏藥物合併指數（Chou and Talalay's combination index）被用來檢驗紫檀芪對於賀癌平（trastuzumab）在治療HER-2過度表現的膀胱癌上之成效影響。結果：在此試驗中，紫檀芪顯現出隨著劑量上升可以激發G0/G1期細胞的數量上升並且降低G2/M以及S期的細胞數量。更甚者，紫檀芪可以引發p27的表現上升以及降低p21的表現。除此之外，此藥物更能下降在HER-2過度表現的T24細胞中磷酸化蛋白激酵素（Akt）的濃度，藉此引發其凋亡。紫檀芪合併賀癌平治療膀胱癌的協同作用在此試驗中被明顯地觀察到。結論：紫檀芪可作為新一代的類胰島素生長因子1受體抑制劑並且可以對於賀癌平在抑制HER-2過度表現的膀胱癌細胞增生上有協同作用。這個結果可以驗證像紫檀芪這類抗類胰島素生長因子1受體之藥物，可以與賀癌平合併使用達到對其有抗性之膀胱癌有更好的療效。

Pterostilbene

10.3966/181020932017121504003

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Location-Aware Cross-Tier Cooperation in Cache-Enabled Heterogeneous Networks

2022 International Wireless Communications and Mobile Computing (IWCMC) (2021)

Tianming Feng Shuo Shi Chenyu Wu Xuemai Gu

Interference management is an interesting topic to be studied in cache-enabled heterogeneous networks (HetNets). In this work, by carefully exploring the relationships among the nearest macro base station (MBS), the nearest small base station (SBS) that stores the requested file, and the nearest SBS that does not store the requested file of a typical user, we propose a location-aware cross-tier cooperation (LCC) scheme to mitigate the cross-tier interference in cache-enabled HetNets. Taking the successful transmission probability (STP) as the performance metric, we firstly derive the expression of it using stochastic geometry. Then, a local-optimal random caching strategy (LORC) that maximizes the STP is obtained. Finally, simulation results verify the effectiveness of the proposed LCC scheme, and demonstrate the advantages of the LORC over three existing caching strategies.

Stochastic geometry

Macro

Base (topology)

10.1109/iwcmc51323.2021.9498678

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Citations (1)

Coverage Characterization of STAR-RIS Networks: NOMA and OMA

IEEE Communications Letters (2021)

Chenyu Wu Yuanwei Liu Xidong Mu Xuemai Gu Octavia A. Dobre

The novel concept of simultaneously transmitting and reflecting reconfigurable intelligent surface (STAR-RIS) is investigated, where incident signals can be transmitted and reflected to users located at different sides of the surface. In particular, the fundamental coverage range of STAR-RIS aided two-user communication networks is studied. A sum coverage range maximization problem is formulated for both non-orthogonal multiple access (NOMA) and orthogonal multiple access (OMA), where the resource allocation at the access point and the transmission and reflection coefficients at the STAR-RIS are jointly optimized to satisfy the communication requirements of users. For NOMA, we transform the non-convex decoding order constraint into a linear constraint and the resulting problem is convex, which can be optimally solved. For OMA, we first show that the optimization problem for given time/frequency resource allocation is convex. Then, we employ the one dimensional search-based algorithm to obtain the optimal solution. Numerical results reveal that the coverage can be significantly extended by the STAR-RIS compared with conventional RISs.

noma

Maximization

Star (game theory)

10.1109/lcomm.2021.3091807

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Citations (160)

An Energy-Efficient Continuous Deployment Scheme for UAV-D2D Networks

ICC 2022 - IEEE International Conference on Communications (2023)

Shuo Zhang Shuo Shi Chenyu Wu Deyou Zhang Xuemai Gu

Unmanned aerial vehicles (UAVs) are regarded as powerful assistance for emergency communications due to their disregard for the limitations of the geographic environment. In this paper, we consider a multi-UAV-assisted wireless emergency communication system, where UAVs are applied as aerial base stations to serve terrestrial device-to-device users (DUs). Our goal is to maximize the UAVs' energy efficiency (EE) through the user grouping strategy with a joint optimization scheme regarding UAVs' trajectories and transmit power. To deal with the resultant mix-integer non-linear programming problem, we divide the optimization process into two stages. In the first stage, we discretize the trajectory into a set of stop points (SPs). Then, the grouping of DUs is achieved by pre-planning the location and optimization range of SPs. In the second stage, with the determined DU grouping strategy, we apply Dinkelbach method and successive convex approximation to convert the original problem into a solvable convex optimization problem. Finally, simulation results verify the effectiveness of our proposed algorithm, which has better performance compared with benchmark schemes in the low user-density region.

Benchmark (surveying)

Transmitter power output

10.1109/icc45041.2023.10279695

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Facile Synthesis of the Sex Pheromone Components of the Legume Pod Borer and Soybean Pod Borer by Suzuki-Miyaura Cross-Coupling Reaction

Letters in Organic Chemistry (2008)

Chenyu Wu Min-Feng Hsien Yao‐Pin Yen

The pheromone components of the legume pod borer, (E,E)-10,12-hexadecadienal, and the soybean pod borer, (E,E)-8,10-dodecadienyl acetate, were synthesized in good yields via Suzuki-Miyaura cross-coupling reactions. Keywords: Synthesis, legume pod borer, soybean pod borer, Suzuki-Miyaura reaction, sex pheromone and (E,E)-10, 12-hexadecadienal

10.2174/157017808785982293

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Citations (3)