Purpose Contact lenses (CLs) used for myopia control incorporate variable power distribution across the optic zone potentially creating degradation of the high-order aberrations. The present study aims to evaluate the retinal image quality and visual performance in three prototypes of CLs intended to control axial elongation of the eye before they are considered for clinical trials.Methods This is a non-dispensing cross-over, double-blind study where 30 right eyes of myopic subjects worn 3 multifocal test lenses and 1 monofocal control lens in random order. Lens 1 was a radial refractive gradient design (center distance) and Lens 2 and 3 center-near with an additional annular ring for near. Nominal add power was 2.00D, 1.50D, and 2.00D, respectively. Subjects had an age 21.96 ± 2.23 years [18–30] and mean spherical equivalent refraction M = −2.23 ± 1.50D [−0.75 to −5.50] with refractive astigmatism below −0.75D. Higher-order aberrations (HOA), glare formation (halo), high- and low-contrast LogMAR visual acuity (VA), and contrast sensitivity function (CSF) was measured under monocular conditions.Results All individual terms of HOA and total root mean square from 3rd to 8th order increased significantly with the 3 test lenses compared to control. Between test lenses, Lens 1 increased significantly the higher HOA compared with Lens 2 and Lens 3. Halo size was significantly larger with test lenses compared with control, with Lens 1 showing the largest. VA under high-contrast conditions was similar for all lenses. Under low-contrast conditions, Lens 1 and Lens 2 performed significantly worse than control (Bonferroni post hoc correction, p < 0.001). CSF was below normal limits with Lens 1 for 3 and 6 cpd spatial frequency but was not significantly different between test lenses and control.Conclusions Lenses with larger stabilized areas for distance vision interfere less with VA and induce lower values of HOA and image degradation.
O objetivo deste trabalho foi estudar o potencial da vinhaça para a produção de biogás, através de um planejamento de experimentos. A vinhaça foi doada pela Usina Ipiranga, Descalvado- SP. Um planejamento fatorial do tipo composto central a dois níveis foi realizado, com dois fatores principais: concentração de vinhaça e pH, cuja a região dos valores foi escolhida de forma a obter um biogás rico em hidrogênio, segundo a literatura. A resposta do planejamento foi a produção de biogás em cada caso. Com os resultados obtidos verificou-se que todos os fatores são significativos, sendo que valores baixos de pH não favorecem a produção de biogás ao passo que valores elevados de concentração de vinhaça favorecem sua produção. Estes valores de concentração indicam possibilidade de se utilizar vinhaça in natura como substrato para a produção de biogás, sendo uma vantagem tecnológica, e operacional.
An urban wastewater treatment plant (WWTP) with two different parallel lines of treatment and located in the north of Portugal was studied during four months, following recurrent episodes of filamentous bulking caused by Sphaerotilus natans and eventual occurrences of Nocardioforms and Type 1863. An aerobic selector was introduced in both lines in the beginning of the studied period, suppressed in one of the lines during six weeks, and then put into operation again until the end of the study. A total of 14 filamentous bacteria morphotypes were identified. The results showed that the presence of an aerobic biological selector in continuous operation prevented the overgrowth of the filamentous Type 1863, of Nocardioforms and, in particular, of S. natans. Simultaneously, it allowed lowering the oxygen levels in the aeration tanks without negative consequences in the overall performance of the WWTP, namely bulking occurrence. Dissolved oxygen (DO) in the aeration tank varied initially between 2 and 3 mg/L, but the introduction of the selector enabled to lower it to 1–1.5 mg/L in the aeration tank and around 0.5 mg/L in the selector. A significant energy save was allowed, even considering the aeration of the selector. The results are more relevant if one considers the fact that the main cause of the bulking problems in this WWTP was the overgrowth of S. natans, a filamentous bacterium known to be stimulated by low DO levels.
A biodigestão anaeróbia é um processo químico de natureza biológica usadapara converter matéria orgânica biodegradável em bioenergia. Nesse trabalho doisplanejamentos de experimentos foram realizados onde a vinhaça foi biodigerida em ensaiosbatelada. Alcançou-se uma produtividade máxima de 1,1 Lbiogás/Lvolume.útil-dia com um pH de 7,3e concentração inicial de substrato de 15 gDQO.L-1. Esse trabalho também permitiu verificar ainfluência de fatores como a população microbiana, observando que lodos com diferentesatividades metabólicas podem afetar consideravelmente a produtividade de biogás.