Reza Vafadoost

Islamic Azad University Medical Branch of Tehran

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Nasrin Esfahanizadeh

Islamic Azad University Medical Branch of Tehran

Hamidreza Daneshparvar

Iranian Legal Medicine Organization

Hamid Ahmadian-Moghadam

Tehran University of Medical Sciences

Hamid Ahmadian Moghadam

Iranian Institute for Health Sciences Research

Mohammad Reza Shabahangfar

Islamic Azad University Medical Branch of Tehran

Banafsheh Salehi

University of California, Los Angeles

Francisco B. Elegado

University of the Philippines Los Baños

D. Aghajani

Shahid Beheshti University

Somaiyeh Azmoun

Florida International University

Solmaz Khalifeh

Islamic Azad University Medical Branch of Tehran

Cooperative Institutions

Tehran University of Medical Sciences

Islamic Azad University Medical Branch of Tehran

Islamic Azad University Central Tehran Branch

Islamic Azad University, Tehran

Iranian Institute for Health Sciences Research

Islamic Azad University Dental Branch of Tehran

University of the Philippines Los Baños

National Drug Addiction Center

University of Tehran

University of California, Los Angeles

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Mineralization potential of Fresh Milk and Mineral Water Treatment on Enamel Surface after Demineralization by Citric Acid

DOAJ (DOAJ: Directory of Open Access Journals) (2022)

Reza Vafadoost Dorsa Aghajani Banafsheh Salehi Hamid Ahmadian-Moghadam

10.22038/jdmt.2022.58188.1447

Cite

Citations (0)

Dental implants in Sjögren syndrome

European Journal of Translational Myology (2020)

Hamidreza Daneshparvar Nasrin Esfahanizadeh Reza Vafadoost

Sjögren's syndrome (SS) is a complex autoimmune disease that predominantly affects the exocrine glands, notably the salivary and lacrimal glands, resulting in dryness of the mucosa recognized as xerostomia. Chief oral complications reported by patients consist of high caries rate, burning sensation of the mucosa, early tooth loss, intensified tooth wear and repetitive failure of dental restorations. In particular, due to the decreased salivary flow, conventional removable prostheses might irritate the mucosa and lead to painful ulcerations at the borders of the denture. Implant-supported prostheses offer a unique solution to the difficulties experienced by edentulous patients with Sjögren’s syndrome. This research showed no signs of peri-implantitis or peri-implant mucositis during 7-years following the placement of implants. The present study indicates that successful long-term maintenance of dental implants can be also achieved in SS patients.

Mucositis

Oral mucosa

Sjögren syndrome

Dry mouth

10.4081/ejtm.2020.8811

Cite

Citations (5)

Production of Bacteriocin by Various Strains of Pediococcus acidilacti during Batch Fermentation and Identification of the Pediocin Structural Genes

Biotekhnologiya (2021)

Reza Vafadoost Francisco B. Elegado D. Aghajani Maria Teresa M. Perez

Bacteriocins are antimicrobial peptides produced by certain bacteria that can be alternatives to traditional antibiotics. This study aimed at evaluating large-scale bacteriocin production by the Pediococcus acidilactici strains in batch fermentation and to analyze the pediocin structural gene (papA) by bioinformatic methods. The fermentation using bacterial strains was carried out in Sartorius Biostat A-Plus Bioreactor, and the bacteriocin production was tested on Listeria innocua as a result of 24 h fermentation. The pediocin structural gene papA was amplified, and the amplicons of each strain were sequenced and analyzed to assess the secondary structure of pediocin and related metabolic pathways. It was shown that the papA structural gene sequence is a conserved region. All strains with a papA amplicon synthesis exhibited active bacteriocin synthesis Keywords: fermentation, Pediococcus acidilactici, purified bacteriocin, pediocin structural gene Funding - The authors acknowledge the grant support by the National Institutes of Molecular Biology and Biotechnology (BIOTECH), Laguna, Philippines.

Pediococcus acidilactici

Pediococcus

Structural gene

10.21519/0234-2758-2021-37-4-20-31

Cite

Citations (0)

Seven Years Follow-up of a Patient with Sjögren's Syndrome Treated with Implant-supported Fixed Prostheses

European Journal of Translational Myology (2020)

Hamidreza Daneshparvar Nasrin Esfahanizadeh Reza Vafadoost

Sjögren's syndrome (SS) is a complex autoimmune disease that predominantly affects the exocrine glands, notably the salivary and lacrimal glands, resulting in dryness of the mucosa recognized as xerostomia. Chief oral complications reported by patients consist of high caries rate, burning sensation of the mucosa, early tooth loss, intensified tooth wear and repetitive failure of dental restorations. In particular, due to the decreased salivary flow, conventional removable prostheses might irritate the mucosa and lead to painful ulcerations at the borders of the denture. Implant-supported prostheses offer a unique solution to the difficulties experienced by edentulous patients with Sjögren’s syndrome. This report and review of the literature discuss a 46-year-old female patient with undiagnosed Sjogren's syndrome successfully treated with dental implants and followed for 7 years.

Oral mucosa

Sjögren syndrome

Dry mouth

10.4081/ejtm.2019.8811

Cite

Citations (3)

Histomorphic Analysis of UV-C Radiation on Osseointegration of Titanium Implants in the Rabbits.

DOAJ (DOAJ: Directory of Open Access Journals) (2022)

Reza Vafadoost Mohammad Reza Shabahangfar Ahad Khoshzaban Hamid Ahmadian Moghadam

Unsuccessful implant integration leads to pain and implant mobility. Implant photo-functionalization by ultraviolet (UV) light has been suggested as a method that may stimulate osseointegration.This study was conducted to analyze the histopathological feature of the titanium implant surface upon treatment with UV-C wave.In this interventional study, twenty rabbits were enrolled. In the treatment groups, the titanium implants, irradiated earlier with UV-C for four hours laterally, were inserted in one of the femur bones. In the control group, the titanium implants without irradiation were inserted in the other femur bone of the rabbits. After two and four weeks, the animals were sacrificed, and then the samples were histologically and histo-morphometrically analyzed. In addition, the amounts of new bone formation, bleeding, and inflammation were recorded, and the data were subjected to statistical analysis.The results confirmed that UV-C irradiation to titanium implants significantly improved new bone formation (p< 0.001). However, no significant new bone formation was observed between two and four weeks after implant insertion (p< 0.098).The study results showed that irradiating titanium implants with UV-C for four hours significantly improves osseointegration and new bone formation but does not considerably affect inflammation or bleeding around the implant. The study suggests that UV-C radiation can increase the success rate of implant treatment.

10.30476/dentjods.2021.91574.1592

Cite

Citations (0)

Tramadol Treatment Induces Change in Phospho-Cyclic Adenosine Monophosphate Response Element-Binding Protein and Delta and Mu Opioid Receptors within Hippocampus and Amygdala Areas of Rat Brain.

PubMed (2021)

Hamid Ahmadian-Moghadam Mitra‐Sadat Sadat‐Shirazi Somaiyeh Azmoun Reza Vafadoost Solmaz Khalifeh

Tramadol induces its unique effects through opioid pathways, but the exact mechanism is not known. The study aims to evaluate changes in the level of mu-opioid receptor (µOR), delta-opioid receptor (δOR), and phosphorylated cyclic adenosine monophosphate (cAMP) response element-binding protein (p-CREB) in the hippocampus (HPC) and amygdala (AL) areas of tramadol-treated rats.For this purpose, a total of 36 male rats were divided into two main groups for chronic or acute tramadol exposure. The animals were then exposed to 5 mg.kg-1 of tramadol, 10 mg.kg-1 of tramadol, and normal saline. The HPC and AL areas of the animals were dissected upon completion of the period. The levels of p-CREB and µOR were quantified using the western blotting technique. The data were subjected to analysis of variance (ANOVA) followed by Tukey's post-hoc analysis. The differences with the P-value lower than 0.05 were considered as significant.In the HPC and AL areas of the brain, the level of µOR was decreased by acute tramadol exposure, while no significant difference was observed by chronic tramadol exposure. Moreover, results showed that the level of p-CREB dose-dependently increased by acute and chronic tramadol exposure.HPC and AL are essential in the control of tramadol abuse. Tramadol abuse affects gene expression and transcription factors such as CREB. With acute drug tramadol treatments, the level of cAMP response element-binding protein (CREB) rapidly increases, while by chronic tramadol treatment, "peak and trough pattern is observing". The activation of the rewarding mechanism is a precise instance of addictive behavior in tramadol-treated individuals.

Cyclic adenosine monophosphate

Adenosine monophosphate

10.22122/ahj.v13i3.306

Cite

Citations (2)