Karlien Raymenants

KU Leuven

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Jan Tack

KU Leuven

Tim Vanuytsel

KU Leuven

Lukas M. Balsiger

KU Leuven

Jolien Schol

KU Leuven

Emidio Scarpellini

Universitair Ziekenhuis Leuven

Florencia Carbone

KU Leuven

Bernhard Scheiner

Medical University of Vienna

Filippo Schepis

University of Modena and Reggio Emilia

José Luís Calleja

Hospital Universitario Puerta de Hierro Majadahonda

Giulia Tosetti

Ospedale Maggiore

Cooperative Institutions

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas

KU Leuven

Instituto de Salud Carlos III

ERN GUARD-Heart

Universitat de Barcelona

Universitair Ziekenhuis Leuven

Consorci Institut D'Investigacions Biomediques August Pi I Sunyer

Centro de Investigación Biomédica en Red

Centre for Biomedical Network Research on Rare Diseases

Hospital Clínic de Barcelona

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Sa1192: MANAGEMENT OF REFRACTORY GERD SYMPTOMS IN EUROPE: EXPERT OPINION IN A CASE-BASED DELPHI APPROACH

Gastroenterology (2022)

Karlien Raymenants Emidio Scarpellini Lukas M. Balsiger Serhat Bor Albert J. Bredenoord

Expert opinion

Delphi

Refractory (planetary science)

Delphi Method

10.1016/s0016-5085(22)60819-9

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Citations (0)

Primary combined lobar/diaphragm resection and liver transplantation for locally advanced alveolar echinococcosis: Report of a challenging case

Journal of Liver Transplantation (2022)

Karlien Raymenants Hannah van Malenstein Jacques Pirenne Diethard Monbaliu Vincent Vandecaveye

In alveolar echinococcosis (AE) radical surgery is still the only curative option. Because of the slow, tumor-like growth with invasion into surrounding tissue, patients usually present late when radical resection with preservation of sufficient functional liver tissue is no longer possible. In end-stage AE, liver transplantation represents an option as palliative treatment for life-threatening complications. We present a case of AE complicated by hepato-pulmonary fistula treated curatively with liver transplantation combined with resection of the right and central diaphragm, part of the pericardium and the inferior right lung. Only few cases with end-stage AE have been treated so far by such extensive surgery. Five years after surgery, PET/CT and MRI imaging are suggestive of limited local recurrence, for which the patient is still treated with albendazole and monitored closely.

Alveolar echinococcosis

Diaphragm (acoustics)

Albendazole

Radical surgery

Surgical oncology

10.1016/j.liver.2021.100058

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Su1653 PREVALENCE AND RISK FACTORS OF EPIGASTRIC PAIN SYNDROME (EPS) AND HEARTBURN OVERLAP, AND CORRELATION WITH H.PYLORI PREVALENCE.

Gastroenterology (2024)

Karlien Raymenants Michael Jones Cedric Van de Bruaene Rina Tanemoto Ami D. Sperber

Heartburn

Epigastric pain

10.1016/s0016-5085(24)02281-9

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433 MANOMETRIC DIAGNOSIS AND TREATMENT OF RETROGRADE CRICOPHARYNGEAL DYSFUNCTION (R-CPD).

Gastroenterology (2023)

Karlien Raymenants Friedel Vulsteke Stijn Arnaert Tim Vanuytsel Jan Tack

10.1016/s0016-5085(23)01163-0

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Citations (1)

Understanding and managing patients with overlapping disorders of gut–brain interaction

The Lancet. Gastroenterology & hepatology (2023)

Lukas M. Balsiger Florencia Carbone Karlien Raymenants Emidio Scarpellini Jan Tack

Confusion

10.1016/s2468-1253(22)00435-6

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Citations (5)

Tu1646 CONFOCAL LASER ENDOMICROSCOPY SHOWS HIGH RATE OF ACUTE MUCOSAL REACTIONS FOLLOWING FOOD ADMINISTRATION IN IRRITABLE BOWEL SYNDROME

Gastroenterology (2023)

Lukas M. Balsiger Jolien Schol Karlien Raymenants Karen Routhiaux Jenas Stevenheydens

Endomicroscopy

10.1016/s0016-5085(23)03489-3

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Review article: Functional dyspepsia—a gastric disorder, a duodenal disorder or a combination of both?

Alimentary Pharmacology & Therapeutics (2023)

Bert Broeders Florencia Carbone Lukas M. Balsiger Jolien Schol Karlien Raymenants

Summary Background Functional dyspepsia (FD) is one of the most frequent conditions in gastroenterological outpatient health care. Most recent research in FD has shifted its focus to duodenal pathophysiological mechanisms, although current treatments still focus mainly the stomach. Aim The aim of the study was to provide a comprehensive overview of the pathophysiology of FD focusing on a paradigm shift from gastric towards duodenal mechanisms. Methods We conducted a literature search in PubMed for studies describing mechanisms that could possibly cause FD. Results The pathophysiology of FD remains incompletely understood. Recent studies show that duodenal factors such as acid, bile salt exposure and eosinophil and mast cell activation correlate with symptom pattern and burden and can be associated with gastric sensorimotor dysfunction. The evolving data identify the duodenum an interesting target for new therapeutic approaches. Furthermore, the current first‐line treatment, that is proton pump inhibitors, reduces duodenal low‐grade inflammation and FD symptoms. Conclusion Future research for the treatment of FD should focus on the inhibition of duodenal mast cell activation, eosinophilia and loss of mucosal integrity.

Pathophysiology

Functional gastrointestinal disorder

10.1111/apt.17414

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Citations (8)

Retrograde Cricopharyngeus Dysfunction, a New Motility Disorder: Single Center Case Series and Treatment Results

Journal of Neurogastroenterology and Motility (2024)

Stijn Arnaert Joris Arts Karlien Raymenants Filip Baert Kathelijne Delsupehe

Retrograde cricopharyngeus dysfunction (R-CPD) is a new clinical entity characterized by inability to belch and associated symptoms of loud gurgling noises, chest and/or abdominal pressure, abdominal bloating, and excessive flatulence. R-CPD can be treated with botulinum toxin (BT) injection in the upper esophageal sphincter. We hereby report patient demographics, symptomatology, and treatment results of a series of consecutive patients who presented at our center.

High resolution manometry

10.5056/jnm23099

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Citations (5)

Tu1365: CASE-BASED EVALUATION SHOWS HIGHLY VARIED APPROACH TO IBS-D TREATMENT BY EUROPEAN EXPERTS

Gastroenterology (2022)

Lukas M. Balsiger Filiz Akyüz Brigida Barberio Serhat Bor Giuseppe Chiarioni

10.1016/s0016-5085(22)62218-2

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Porto sinusoidal vascular liver disorder: natural history and long-term outcome

Journal of Hepatology (2023)

Marta Magaz Heloïse Giudicelli-Lett Juan G. Abraldeṣ Oana Nicoară-Farcău Neil Rajoriya

10.1016/s0168-8278(23)00576-7

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Citations (3)