Vlad Pieptu

Grigore T. Popa University of Medicine and Pharmacy

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Alexandru Mihai

National Institute of Research and Development for Biological Sciences

Doina Azoicăi

Grigore T. Popa University of Medicine and Pharmacy

Nicolae Gheţu

Institutul Regional de Oncologie

Dragoș Pieptu

Grigore T. Popa University of Medicine and Pharmacy

Vladimir Poroch

Grigore T. Popa University of Medicine and Pharmacy

Diana Cimpoieşu

Grigore T. Popa University of Medicine and Pharmacy

Lucian Miron

Institutul Regional de Oncologie

Dan Ferariu

Institutul Regional de Oncologie

Costin Groza

Grigore T. Popa University of Medicine and Pharmacy

Nicolae Ioanid

Institutul Regional de Oncologie

Cooperative Institutions

Grigore T. Popa University of Medicine and Pharmacy

Institutul Regional de Oncologie

Spitalul Clinic de Recuperare

Creative Commons

Carol Davila University of Medicine and Pharmacy

Spitalul Clinic Judeţean de Urgenţe "Sf. Spiridon" Iaşi

Institut de Biologie et de Chimie des Protéines

Centre National de la Recherche Scientifique

Advanced Neural Dynamics (United States)

Alexandru Ioan Cuza University

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Romanian Journal of Legal Medicine (2019)

Vlad Pieptu Alexandru Mihai Răzvan Grecu Diana Bulgaru-Iliescu Doina Azoicăi

Burn center

Center (category theory)

10.4323/rjlm.2019.28

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Epidemiology of hospitalized burns in Romania: A 10-year study on 92,333 patients

Burns (2021)

Vlad Pieptu Roxana Moscalu Alexandru Mihai Mihaela Moscalu Dragoș Pieptu

10.1016/j.burns.2021.05.020

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Bilateral V-Y advancement gluteal fold flaps following vulvo-vaginal melanoma resection

Archive of Clinical Cases (2015)

Vlad Pieptu Alexandru Mihai Nicolae Gheţu Nicolae Ioanid Dan Ferariu

The soft tissue defects of the anterior perineum can be caused by tumour excision, trauma, burns, Fournier’s gangrene and genital mutilation. Various reconstruction methods were described: vacuum-assisted closure, skin grafts and skin substitutes, pedicled or free flaps. In the case of defects following oncologic surgery, flaps are the reconstructive method of choice. We present the case of a 65 year-old woman diagnosed with stage III A vulvo-vaginal melanoma affecting also the distal urethra. Radical vulvectomy and en-bloc excision of the anterior third of the vagina and distal urethra, along with bilateral inguinal lymphadenectomy was performed. The resulting defect was covered with bilateral V-Y advancement gluteal fold flaps. A local vaginal recurrence appeared 18 months after surgery and was safely removed. The patient followed chemotherapy with Dacarbazine. The gluteal fold flap offered good defect coverage and survived completely. Follow-up period was two years without distant metastases. Functional result was excellent, urinary function being normal and patient satisfaction high. Due to the gluteal flap’s advantages (appropriate thickness, good vascularity, minimal donor site morbidity, and same operative field allowing for shorter operating time), reconstruction of the anterior perineum after oncological resection with bilateral V-Y advancement gluteal flaps is a viable solution.

Wide local excision

Radical Vulvectomy

Gluteal region

10.22551/2015.07.0203.10047

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EPIDEMIOLOGY OF BURNS IN IAȘI COUNTY, A 10-YEARS STUDY

The Medical-Surgical Journal (2020)

Vlad Pieptu Adriana Mihai Doina Azoicăi

This study intends to obtain a baseline epidemiological evaluation regarding hospitalizations for burns cases in Iași County. Material and methods: We performed an epidemiological descriptive study of all hospital admitted burns patients from Iași County, for a period of 10 years, from 2006 to 2015. Data used in this study originates from standard government collected information upon hospital discharge and freely available public demographic information. Statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS). Results: There were a total of 3,065 residents of Iași County hospitalized for burn-related causes in the studied period. Monthly distribution showed an average of 25.5 cases, with peaks in December (30.3 cases/month) and July (29.1 cases/month). Males represented 56% of cases and Male to female Ratio period was 1.27:1. The urban/rural proportion averaged 1:1.55. Average length of stay had a mean value of 9.79 days, while average median length of stay was 7.5 days. A total of 106 deaths were reported. Mortality expressed as deaths-to-cases ratio resulted in 3.54% for the overall period. Conclusions: This is the first study upon the epidemiology of burns in Romania in the last 30 years. The studied group presents a strong rural predominance with an increasing trend, and a decrease of annual case numbers combined with an increase in burn-related deaths. Quality of collected data is critical towards a precise overview and specific indicators are needed in reporting burns.

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Burns in the Emergency Department: A One-Year Single Center Analysis on 355 Cases

Chirurgia (2020)

Vlad Pieptu Alexandru Mihai Costin Groza Corneliu Gheorghiţă Diana Cimpoieşu

Background: Burns are common reasons for emergency department presentations. While extensive or special burns require treatment in a specialized center, the majority are amenable to ambulatory treatment or hospitalization in a surgical ward. Romania has a national data collecting mechanism regarding all hospitalized patients, but there are no available statistics concerning non-hospitalized burn cases. This study aims to explore the amplitude of burn trauma by analyzing data from an Emergency Department at a major Romanian regional trauma center. Methods: This is a retrospective single-center 1-year study of all burn-related emergency department presentations at the trauma referral center for Romania's North-East region, in 2015. Included in the study were all cases of burns, indiscriminate of their etiology. Results: A total of 355 burn cases were analyzed. The average monthly number of cases was 29.58, with a maximum of 54 and a minimum of 18. There were 206 males and 149 females and 57.7% urban residents. Only 134 cases have been hospitalized during this period. Conclusions: Almost two-thirds of cases have not been hospitalized, thus missing from national statistics. Precise epidemiological data is paramount for a successful national burn management strategy. Creation of a national burn registry is suggested.

Burn center

Trauma Center

Etiology

10.21614/chirurgia.115.4.486

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Citations (4)

Integra for penile coverage after traumatic degloving – case report

Archive of Clinical Cases (2014)

Vlad Pieptu Alexandru Mihai Nicolae Gheţu

Penile soft tissue defects can be caused by tumor excision, trauma, burns, Fournier’s gangrene and self-mutilation. Reconstruction of such defects has been achieved through various methods (local or regional flaps, full-thickness or split-thickness skin grafts, skin substitutes). Although no consensus has been reached, it seems that split thickness skin grafts are the method of choice. Penis resurfacing is a delicate procedure, especially in potent men, as it aims normal coverage, sensibility, aesthetic aspect and restoring erectile function with sexual satisfaction. We present a case of traumatic avulsion of the anterior perineum successfully treated using split thickness skin grafts for the testicles and Integra for the penis. The follow-up period was 5 years. Functional result was excellent, the penile skin regaining its elasticity, flexibility and pliability. No urinary problems or erectile dysfunctions were noted. Due to its advantages (skin elasticity, limited hypertrophic scar formation and inhibited myofibroblasts contraction) Integra might be the optimal penile coverage solution.

Degloving

Penile Fracture

Penectomy

10.22551/2014.04.0103.10021

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