AIM: By investigating the detected rate of Helicobacter pylori(H.pylori) in the stomach following dental plaque control in patients,to provide new evidence on the correlated relationship of H.pylori between dental plaque and gastric mucosa and clarify the necessity of strategy of dental plaque controlling on those patients.METHODS: 80 patients with eradicated H.pylori of their gastric mucosa were selected.Dental plaque was controlled completely in the test group.Patients without dental plaque control were assigned in to control group.All patients were conducted by 13C-urea breath test again after half a year to determine the detected rate of H.pylori of their gastric mucosa.RESULTS: Detected rate of H.pylori in the test group was lower significantly than that in the control group(P0.05).CONCLUSION: There was significant association between dental plaque and gastric H.pylori infection.Dental plaque control procedures should be performed in the treatment of gastritis and peptic ulcer.
Objective
To explore the effects of clinical nursing path in the nursing of children with acute diarrhea.
Methods
A total of 80 cases of acute diarrhea children were enrolled from August 2014 to August 2017 in the First Hospital of Jilin University as the research object, and randomly divided into 2 groups with 40 cases in each group. The control group were given routine nursing, and the observation group received clinical nursing path. The time of antidiarrheal, the time of antipyretic, the time of normal stool recovery, the time of vomiting disappearance, the time of hospitalization, the recurrence and the degree of satisfaction of the family members were compared between the two groups.
Results
The time of antidiarrheal, the time of antipyretic, the time of normal stool recovery, hospitalization time and recurrence rate of the observation group were all lower than those of the control group. The scores of family members' satisfaction on communication and information support, emotional support and quality nursing support of the observation group were higher than those of the control group, and the differences were statistically significant (P 0.05) .
Conclusions
The clinical nursing path can effectively relieve the clinical symptoms of children with acute diarrhea, improve their family satisfaction and reduce the recurrence rate.
Key words:
Diarrhea; Nursing path; Children; Acute
Abstract Background: Circular RNAs play an important regulatory role in the occurrence and development of nerve damage and related diseases, but there is little research on non-coding RNAs in heat sickness, especially circRNAs, and there has been no report on the mechanism of fever progression. Methods: 1. Mice were randomly divided into a control group, a heat radiation disease 0.8 h group (HS 0.8), 8 h group (HS 8), 24 h group (HS 24). By establishing a mouse model of heat shock (HS), heat-damaged brain tissue was obtained, microglia were isolated. 2. QPCR was used to detect M1 and M2 marker molecules in microglia, and to evaluate the polarization direction and type of microglia. 3. The expression level of circhipk3 in microglial cells, and the effect of circhipk3 on microglial polarization was determined by determining the expression of circhipk3 in microglial cells. Results: The expressions of CD45 and CD11-b in the HS 8 group were significantly higher than those in the normal group, while the expressions of CD45 and CD11-b in the HS 24 group were significantly lower than those in the HS 8 group. At the same time, the expression of CD206, FIZZ, and Arg1 in the HS 8 group began to increase compared with the normal group, while CD206, FIZZ, and Arg1 in the HS 24 group significantly increased when compared with the normal group. Circhipk3 mimics significantly increased the expression of Arg1 and inhibited the expressions of CD45 and HO-1, while the circhipk3 inhibitor promoted the expressions of CD45 and HO-1 and inhibited the expression of Arg1. Conclusion: Microglial cells were the main M1-type in early neurological injury of heat radiation disease. HO-1 may be one of the microglial M1-type markers. The high expression of circhipk3 in microglial cells mainly promoted its transformation to the M2 type.
Background: Acupuncture can be used in clinical practice to promote motor recovery in patients with acute ischemic stroke and paralysis. It is an economical, safe, and effective method that can be easily implemented in clinical settings. However, although scalp acupuncture is an easy-to-perform micro-needle therapy, its efficacy in the treatment of hemiplegia resulting from acute ischemic stroke remains disputed. Methods/Design: This is a randomized parallel-controlled single-blind trial. It will be performed at the Department of Neurology, Second Hospital, Lanzhou University, China. Seventy-two patients suffering from acute ischemic stroke with paralysis will be randomly assigned to undergo 14 days of either conventional drug treatment (control group) or conventional drug treatment combined with scalp acupuncture that uses the twirling-needle method (once a day, 6 consecutive days followed by 1 day off per week). The primary outcome is the difference in National Institutes of Health Stroke Scale (NIHSS) scores between just after the stroke and 14 days after treatment. Secondary outcomes include motor recovery (assessed by the Fugl-Meyer Motor Scale) and activities of daily living (assessed by the Barthel index). Discussion: Objectively evaluating the efficacy of twirling-needle scalp acupuncture in the treatment of hemiplegia after acute ischemic stroke will provide evidence for assessing whether this method can improve motor recovery from hemiplegia resulting from acute ischemic stroke. Trial registration: This trial has been registered on 11 March 2016 in the Chinese Clinical Trial Registry (registration number: ChiCTR-IOR-16008083). Ethics: This trial has been approved by Ethics Committee, Second Hospital, Lanzhou University of China (approval number: 2016A-003) and will be performed in accordance with the Declaration of Helsinki, formulated by the World Medical Association.Informed consent: Written informed consent will be obtained from the patients and their relatives.
The development of leukemia after chemotherapy and/or radiotherapy for breast cancer has been recognized for 4 decades. In this issue, Churpek et al have conducted a retrospective study that expands on a growing body of knowledge for understanding an individual's genetic risk, not only for breast cancer, but also for second cancers such as leukemia.
Aberrant expression of several types of miRNAs has been reported in acute myocardial infarction (AMI). The objective of our study was to compare miRNA expression in AMI patients and normal healthy people and determine whether miR-26a, miR-191, and miR-208b could be measured in plasma as indicators for AMI. Detection of AMI patients and normal persons by using miRNA microarray chip analysis and miR-26a, miR-191, and miR-208b was screened out. Eighty-seven AMI patients and eighty-seven homogeneous healthy individuals were recruited. Total mRNA including miRNA was isolated and miR-26a, miR-191, and miR-208b expression were determined by qRT-PCR. Receiver operating characteristic curve analysis was performed to evaluate the instructive power of miR-26a, miR-191, and miR-208b for AMI. Dual-luciferase reporter assays indicated p21 is a direct target of miR-208b. miR-26a and miR-191 were low expressed in AMI compared with normal healthy people, but miR-208b was expressed at a high level in AMI. miR-26a showed an area under the curve (AUC) of 0.745, with a sensitivity of 73.6 % and a specificity of 72.4 %.The AUC for miR-191 was 0.669, with a sensitivity of 62.1 % and a specificity of 69.0 %.The AUC for miR-208b was 0.674, with a sensitivity of 59.8 % and a specificity of 73.6 %. miR-208b was significantly increased in the AMI compared with healthy people, while miR-26a and miR-191 were decreased. miR-26a, miR-191, and miR-208b were potential indices of AMI, and miR-208b was more effective in patients with non-ST-elevation myocardial infarction.
Objective To analyze problems of nursing reviews written by 60 trainees attending Nurse Specialist Certification Class,in order to provide references for better training and improve their level of scientific research.Methods Nursing reviews written by 60 trainees attending Nurse Specialist Certification Class were chosen by convenience sampling,and Criteria for nursing reviews by Beijing Nursing Institute was used for evaluation.Problems were summarized and analyzed.Results The average score of reviews was (75.97 ± 8.38),and the main problems included topic selection,preface,main part and summary writing.Conclusions The level of review writing is relatively low in clinical nurses who should improve their research awareness,and training as well as management on nurse specialists' review writing is extremely necessary.
Key words:
Review; Writing; Nurse specialist
Objective To investigating the condition of self-care agency in nursing undergraduates,to provide the basis for promoting the self-care agency.Methods A total of 150 nursing undergraduates who came from Harbin Medical College were investigated by the Chinese version of the exercise of self-care agency scale (ESCA).The stepwise regression analysis was carried out which was the self-care responsibility,the self-conception,the self-care skills and the health knowledge as the dependent variables and the personal data as independent variables.Results The scores of all dimensions of ESCA from low to high in order were respectively the sense of self-care responsibility (12.44 ± 4.320),the self-conception (23.25 ± 4.350),the self-care skills (31.94 ± 6.780) and the health knowledge (42.76 ± 7.900).The personal data had no effect on self-care responsibility,the self-conception,the self-care skills and the health knowledge.Conclusions The self-care agency of the undergraduate students should be enhanced.
Key words:
Self-care; Nursing undergraduates; Exercise of self-care agency scale
'/%3e%3cuse xlink:href='%23a' transform='rotate(23.036 .093 25.536)'/%3e%3cuse xlink:href='%23a' transform='rotate(45.87 1.273 16.18)'/%3e%3cuse xlink:href='%23a' transform='rotate(69.945 .996 12.078)'/%3e%3cuse xlink:href='%23a' transform='rotate(20.66 -19.689 31.932)'/%3e%3c/svg%3e)
