Roberta Rossi

IRCCS Humanitas Research Hospital

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Sara Massironi

IRCCS Ospedale San Raffaele

Ettore C. degli Uberti

University of Ferrara

Dario Conte

Institute of Atmospheric Sciences and Climate

Maria Chiara Zatelli

University of Ferrara

Giorgio Trasforini

Arcispedale Sant'Anna

Brunangelo Falini

University of Perugia

Maria Paola Martelli

Ospedale Santa Maria

Martyn Caplin

Royal Free London NHS Foundation Trust

Alessandro Repici

IRCCS Humanitas Research Hospital

Federica Cavalcoli

Fondazione IRCCS Istituto Nazionale dei Tumori

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Istituti di Ricovero e Cura a Carattere Scientifico

263

University of Milan

162

Sapienza University of Rome

100

University of Perugia

University of Ferrara

University of Bologna

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Humanitas University

Fondazione IRCCS Istituto Nazionale dei Tumori

IRCCS Humanitas Research Hospital

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ANALISI DELLE CARATTERISTICHE PRESCRITTIVE DEGLIANTIBIOTICI ALLA DIMISSIONE IN PAZIENTI IN SORVEGLIANZAEPIDEMIOLOGICA PER IL RISCHIO DI INFEZIONE DEL SITOCHIRURGICO NELL’AZIENDA OSPEDALIERO-UNIVERSITARIA DIFERRARA (AOUFE) NEL QUARTO TRIMESTRE 2014

Andrea Formaglio Paola Antonioli Marco Libanore Monica Pantaleoni Carlo Contini

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Anti-tumour necrosis factor agent and liver injury: Literature review, recommendations for management

World Journal of Gastroenterology (2014)

Roberta Rossi

Abnormalities in liver function tests, including transient and self-limiting hypertransaminasemia, cholestatic disease and hepatitis, can develop during treatment with anti-tumour-necrosis-factor (TNF) therapy.The optimal management of liver injury related to anti-TNF therapy is still a matter of debate.Although some authors recommend discontinuing treatment in case of both a rise of alanine aminotransferase more than 5 times the upper limit of normal, or the occurrence of jaundice, there are no standard guidelines for the management of anti-TNF-related liver injury.Bibliographical searches were performed in PubMed, using the following key words: inflammatory bowel disease

Liver disease

Liver function

10.3748/wjg.v20.i46.17352

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Crisi distrofiche e variazioni della associazione a bivalvi in una Sacca del Delta del Po.

Piero Franzoi Michele Mistri Roberta Rossi Victor Ugo Ceccherelli

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Sessualità ed infertilità di coppia

Maria Luisa Moro Manuela Carrara Cristina Iacchia Alberto Oliet Palá Gerardo Rossetto

Lo stress psicologico correlato alla condizione di infertilita, la finalizzazione dell’atto sessuale alla riproduzione e l’interferenza dello staff medico nell’attivita sessuale possono rappresentare nella coppia infertile fattori di rischio per la sessualita. Obiettivo della ricerca e stato lo studio del comportamento sessuale di 100 coppie candidate ad un programma di riproduzione assistita nei sei mesi precedenti alla consultazione. Il campione e stato suddiviso a seconda del fattore di infertilita di coppia ed i partner sono stati sottoposti ad una intervista semistrutturata, differenziata per genere, formulata in base ai criteri del DSM IV per la diagnosi delle disfunzioni sessuali. Alle coppie e stato inoltre richiesto, con un quesito posto sotto forma di domanda aperta, se ritenessero che la condizione di infertilita avesse modificato il loro comportamento sessuale. I risultati hanno evidenziato una maggiore incidenza di disagio e disfunzioni sessuali nelle donne infertili rispetto agli uomini. Il desiderio sessuale ipoattivo e la disfunzione sessuale che piu frequentemente e stata correlata alla condizione di infertilita in entrambi i sessi. In conclusione sembra importante offrire alle coppie infertili afferenti ai programmi di riproduzione assistita un counseling sessuologico mirato alla prevenzione, alla diagnosi e al trattamento delle disfunzioni sessuali, anche in vista della relazione tra comportamento sessuale e fertilita.

10.1400/66847

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Middle term follow-up results of sentinel lymph node (SLN) detection in differentiated thyroid carcinoma

The Quarterly Journal of Nuclear Medicine and Molecular Imaging (2009)

Luciano Feggi Stefano Panareo Paolo Carcoforo Napoleone Prandini Melchiore Giganti

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Prevalence of Osteopathy In Chronic Pancreatitis: A Systematic Review and Meta-Analysis

Clinical and Translational Gastroenterology (2023)

Daryl Ramai Antonio Facciorusso Marcello Maida Gabriele Capurso Saurabh Chandan

Individuals with chronic pancreatitis (CP) are at increased risk for nutritional complications during their clinical course. We appraised the literature to provide updated estimates of the prevalence and predictors of osteoporosis, osteopenia, and osteopathy in CP using a systematic review and meta-analysis.Search strategies were developed for major databases from inception through October 2021. Outcomes of interest included rates of osteopenia and osteoporosis based on dual-energy X-ray absorptiometry scans and risk factors. A random-effects model was used for analysis, and results were expressed as pooled cumulative rates along with 95% confidence interval (CI).From an initial total of 1,704 identified articles, we ultimately selected 17 studies that involved 1,659 subjects (n = 1,067 men) with CP. The pooled rate of osteopathy was 58% (95% CI: 49%-67%; P < 0.001; I 2 = 91.8%). The pooled rate of osteoporosis was 18% (95% CI: 12%-23%; P < 0.001; I 2 = 86.3%), and the pooled rate of osteopenia was 39% (95% CI: 31%-48%; P < 0.001; I 2 = 91.53%). In the systematic review, factors associated with decreased bone mineral density included smoking, alcohol consumption, older age, female sex, low body mass index, decreased vitamins D and K, and fecal elastase levels.Patients with CP have high rates of osteopathy when assessed with dual-energy X-ray absorptiometry imaging. Additional studies with longitudinal follow-up are needed to understand the observed heterogeneity, the cumulative burden of disease, and rate of bone loss in CP.

Osteopenia

Osteopathy

10.14309/ctg.0000000000000623

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Faculty of 1000 evaluation for Quality of sexual life of women on oral contraceptive continued-regimen: pilot study.

F1000 - Post-publication peer review of the biomedical literature (2013)

Chiara Simonelli Roberta Rossi Marco Silvaggi

Sexual life

Regimen

10.3410/f.717974266.793478331

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P.04.15 CAN NEUTROPHIL-TO-LYMPHOCYTE RATIO (NLR) PREDICT CLINICAL OUTCOMES OF PANCREATIC NEUROENDOCRINE TUMORS (PanNETs)?

Digestive and Liver Disease (2018)

Sara Massironi Roberta Rossi Clorinda Ciafardini Alessandra Zilli Federica Cavalcoli

Pancreatic neuroendocrine tumor

10.1016/s1590-8658(18)30483-3

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Double-Balloon Enteroscopy in Detecting Small-Bowel Neuroendocrine Neoplasms: A Single-Center Prospective Study

Digestion (2020)

Roberta Rossi Luca Elli Federica Branchi Dario Conte Sara Massironi

Background and Aim: Small-bowel neuroendocrine neoplasm (sbNEN) diagnosis has improved with double-balloon enteroscopy (DBE). DBE efficacy in the detection of sbNENs is unknown. We aimed to report the experience at a single referral center for NENs. Methods: All consecutive patients with a suspected sbNEN selected for diagnostic DBE were enrolled. Results: Between 2011 and 2016, 25 patients were referred for a suspected sbNEN. In 15/25 patients, a primary NEN was detected outside the small bowel; in 4, NEN was excluded. After extensive workup, 6 patients (4 males, median age 50 years) underwent DBE (3 anterograde, 2 retrograde, and 1 both; median time: 60 min; median insertion 200 cm). DBE was positive in 3 patients: one had an ileal 2-cm NEN G1, one had an ileal 1.3-cm NEN G1, and one had an ileal 1-cm NEN G2, all surgically removed. Of the 3 other patients, one had a metastatic NEN of unknown primary, the other two had small intestinal NENs, both surgically removed (1.6-cm G1 and G2 NEN). DBE showed a sensitivity of 60% and, in absence of false-positive results, a specificity of 100%. Accuracy resulted 67%. No complications were observed. Conclusions: In line with data from the literature, the present series showed that DBE is a safe and effective procedure in the diagnosis of sbNENs. Further studies are needed to better clarify the diagnostic role of DBE in the neuroendocrine tumor setting and its relationship with other techniques.

Double-Balloon Enteroscopy

Enteroscopy

Single Center

10.1159/000511850

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“In vitro” and in Animal Model Studies on a Double Virus- Inactivated Factor VIII Concentrate

Thrombosis and Haemostasis (1995)

S. Arrighi Roberta Rossi Maria Giuseppina Borri Vladimir Lesnikov Marina Lesnikov

To improve the safety of plasma derived factor VIII (FVIII) concentrate, we introduced a final super heat treatment (100 degrees C for 30 min) as additional virus inactivation step applied to a lyophilized, highly purified FVIII concentrate (100 IU/mg of proteins) already virus inactivated using the solvent/detergent (S/D) method during the manufacturing process. The efficiency of the super heat treatment was demonstrated in inactivating two non-lipid enveloped viruses (Hepatitis A virus and Poliovirus 1). The loss of FVIII procoagulant activity during the super heat treatment was of about 15%, estimated both by clotting and chromogenic assays. No substantial changes were observed in physical, biochemical and immunological characteristics of the heat treated FVIII concentrate in comparison with those of the FVIII before heat treatment.

Animal model

10.1055/s-0038-1649839

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Citations (13)