Abstract Trace elements are essential micronutrients for the human body. In this study, we evaluated the alterations in copper, chromium, manganese, selenium, magnesium, zinc, iron, arsenic, boron, and silicon levels in children with cyanotic and acyanotic CHD who underwent cardiac surgery with cardiopulmonary bypass. Participants were divided into the following three groups: patients acyanotic CHDs (n=34), patients with cyanotic CHDs (n=30), and healthy controls (n=30). Blood samples were collected before the surgery and 1 hour after the sternum was closed. Serum trace elements were determined by Inductively Coupled Plasma Optical Emission Spectrometer-ICAP 6000. The baseline serum arsenic, manganese, and zinc levels of both patient groups were lower compared with controls, but there was no significant difference between baseline serum trace element levels of cyanotic and acyanotic patients. In both the patient groups, there was a significant decrease in postoperative serum arsenic, boron, copper, and zinc levels, and a significant increase in postoperative serum iron and magnesium levels. Silicon levels increased in cyanotic patients. Alterations in trace element levels were in the same direction in cyanotic and acyanotic patients. Copper, zinc, and manganase replacement may be needed after on-pump cardiac surgery.
ECMO Geçmiş, Bugün ve Gelecek Melek YILMAZ ECMO Fizyolojisi Ülkü KAFA KULAÇOĞLU Endikasyonlar Kontrendikasyonlar Güncel Kılavuzlar Cihan YÜCEL ECMO Ekipmanları, Set Gereksinimleri ve Kurulum Tarık DEMİR Genel Prensipler, Kanulasyon ve Dekanulasyon Abdul Kerim BUĞRA Venoarteriyel ECMO Elif GÜNEYSU Candan ÖZTÜRK Venö-Venöz ECMO Serkan KETENCİLER ECMO Tedavisinde Takip ve Yönetim Burçin ÇAYHAN KARADEMİR ECMO’dan Ayrılma, Kriterler ve İşleyiş Timuçin AKSU ECMO ve Renal Replasman Tedavileri Burak ERSOY Pulmoner Embolizmde ECMO ve ECMO destekli girişimler Mehmed YANARTAŞ ECMO Destekli Kardiyopulmoner Resusitasyon: E-CPR Öner BOZAN Göğüs Cerrahisinde ECMO Onur DERDİYOK ECMO ve Plazmaferez Emre YAŞAR ECMO Mekanik Komplikasyonları Mehmet ATAY ECMO Hastalarında Nörolojik Komplikasyonlar Zeynep Vildan OKUDAN ATAY ECMO’nun Ventriküler Destek Cihazları ve Transplantasyona Köprü Aşamasındaki Rolü Aybala TONGUT Mobil ECMO: Kritik Hasta Transferindeki Rolü Okan UĞURLU ECMO Sırasında Gelişen Spesifik Sorunlar ve Çözümleri Behzat TÜZÜN COVID-19 Pandemisinde ECMO Haluk Mevre ÖZGÖZ ECMO Eğitiminde Simulasyonun Rolü Ercan SERVET ECMO Takımı Organizasyonu ve Çalışma İlkeleri Mobil ECMO Takımı Ali ARIKAN ECMO Hemşire Takibi Meral EKŞİOĞLU ECMO Sonuçları: Sağ Kalım ve Hayat Kalitesi İbrahim YILDIZHAN ECMO Koagulasyon Yönetimi Güncel Tartışmalar Meliha Zeynep KAHRAMAN ECMO ve İnflamatuar Yanıt Z.Özlem ULUBAY ECMO ve Sağlık Ekonomisi Canan METINOĞLU GÜRSOY Mete GÜRSOY ECMO ve Etik Hususlar Yusuf ÇETİN Anıl AKBAŞ Uyanık ECMO Mehmet KÖSEOĞLU Miyokarditte ve Nadir Kardiyomiyopatilerde ECMO Ali Aycan KAVALA Yusuf KUSERLİ Onur Emre SATILMIŞ İlaç Zehirlenmesinde ECMO Saygın TÜRKYILMAZ Hasan TOZ Selim TÜMKAYA Hipotermi İçin ECMO Yusuf KUSERLİ Mehmet Ali YEŞİLTAŞ Hasan TOZ Girişimsel Kardiyak İşlemler Sırasında ECMO Kullanımı Yalçın DALGIÇ Ekstrakorporal CO2 Uzaklaştırılması (ECCO2r) Altay Nihat ACAR Ahmet ESKİOCAK
Ventricular assist devices (VADs) are an important technological development for patients with end-stage heart failure, and approximately 50% of these patients require various additional cardiac procedures.Here we presente the case of a patient suffering from severe aortic insufficiency, aortic root dilatation, and an ascending aortic aneurysm with end-stage decompensated heart failure.We performed the Bentall procedure combined with a left VAD implantation during the same session.The postoperative period was uneventful for this patient, and he was discharged on the 32nd postoperative day.The heart failure symptoms of the patient are reasonable, and he is still on the heart transplantation waiting list.
Abstract Ventricular assist devices (VADs) are an important technological development for patients with end-stage heart failure, and approximately 50% of these patients require various additional cardiac procedures. Here we presente the case of a patient suffering from severe aortic insufficiency, aortic root dilatation, and an ascending aortic aneurysm with end-stage decompensated heart failure. We performed the Bentall procedure combined with a left VAD implantation during the same session. The postoperative period was uneventful for this patient, and he was discharged on the 32nd postoperative day. The heart failure symptoms of the patient are reasonable, and he is still on the heart transplantation waiting list.
Background: This study aims to investigate the risk factors and surgical outcomes of conversion to median sternotomy in minimally invasive direct coronary artery bypass grafting. Methods: Between January 2017 and July 2022, a total of 274 patients (246 males, 28 females; mean age: 57.0±9.6 years; range, 33 to 81 years) who underwent conventional (n=116) or robot-assisted (n=158) minimally invasive direct coronary artery bypass grafting were retrospectively analyzed. The primary outcome measure of the study was conversion to median sternotomy, and the secondary outcome measures were operative mortality, length of intensive care unit and hospital stay. Results: Conversion to median sternotomy was required in 26 (9.5%) patients. The most common cause of conversion was intramyocardial left anterior descending artery (27.0%). Among preoperative and operative characteristics, only age was statistically significant risk factor for conversion to sternotomy (odds ratio=1.06, p=0.01). Operative mortality occurred in one patient (0.36%) patient in the entire cohort. The length of intensive care unit and hospital stay was significantly longer in patients requiring conversion to median sternotomy (p=0.002 and p<0.001, respectively). There was no significant difference in other postoperative outcomes between the two groups (p>0.05). Conclusion: Intramyocardial left anterior descending artery is the most common reason for conversion to sternotomy, and older age increases the risk of conversion. Minimally invasive coronary artery bypass grafting can be performed with satisfactory results, even if it requires conversion to sternotomy.
Ozet Bu arastirma Ahi Evran Universitesi Egitim ve Arastirma Hastanesi Eriskin Yogun Bakim Unitesinde intoksikasyon tanisi ile tedavi edilmis hastalarin verilerini derlemek ve diger arastirma verileriyle karsilastirmak amaciyla yapildi. Ahi Evran Universitesi Egitim ve Arastirma Hastanesi Eriskin Yogun Bakim Unitesi’nde 01.06.2013–01.06.2014 tarihleri arasinda intoksikasyon tanisiyla tedavi gormus hastalarin dosyalari retrospektif olarak incelendi. Hastalarin yaslari, cinsiyetleri, ogrenim durumlari, ozgecmisleri, etkilenilen toksik madde, ve toksik madde sayisi, toksik madde alma sekilleri, toksik madde temin etme yollari, Glaskow koma skorlari, hastaneye basvuru sureleri, mekanik ventilasyon ihtiyaclari, komplikasyonlar, yogun bakimda kalis sureleri, yogun bakimdan cikis sekilleri kaydedildi. Yaslari 14-85 arasinda 87 hasta tedavi edilmistir. Hastalarin yas ortalamasi medyan 27.56’dir. Hastalarin %72.4’u kadin, %27.6’si erkektir. %98.9’u intihar amacli ilac almistir. Kullanilan ilaclar sirasiyla analjezik, antidepresan, antipsikotik, antigribal, antibiyotik, antiepileptik, antihipertansiflerdir. Intoksikasyona neden olan ilac disi maddeler ise organofosfat, fare zehirli bugday, temizlik kimyasallaridir. Hastalarin %46’si onceden antidepresan tedavi gormus, %4.6’si daha once de intihar girisiminde bulunmustur. Hastalarin %51.7’si ilaca ilk maruz kaldiktan 1 saat sonra hastaneye getirilmistir. Hastalarin %50.6’si tek, geri kalani cok sayida ilac almistir. Yogun Bakim servisine geldiklerinde hastalarin %81.6’sinda Glaskow skoru 15 olarak saptanmistir. Iki hastada mekanik ventilasyon ihtiyaci olmustur. Hastalarin %64.4’u servise devredilmis, %33.3’u taburcu edilmistir. Mortalite oranimiz %2.3 olup, kadinlarda mortalite gorulmemistir. Bircok merkezde yapilan calismalara benzer olarak, Yogun Bakim servisimizde intoksikasyon nedeniyle tedavi edilen hastalarin cogunlugunu intihar amacli ilac alan genc kadinlar olusturmaktadir. Ilac olarak siklikla analjezik ve antidepresan kullanilmistir. Anahtar kelimeler: Intihar, Intoksikasyon, Yogun bakim servisi Abstract This study was conducted to review the data of patients treated with the diagnosis of intoxication in Ahi Evran University Training and Research Hospital Adults Intensive Care Unit and to compare those data with other research. The files of patients treated with the diagnosis of intoxication in Ahi Evran University Training and Research Hospital Adults Intensive Care Unit between 01.06 2013 and 01.06. 2014 were examined. Age, gender, educational status, history, toxic substance or number of toxic substances by which being influenced, ways of taking toxic substances, ways of supplying toxic substances, Glasgow coma score, admission time to hospital, mechanical ventilation requirements, complications, length of stay in intensive care unit, ways of leaving intensive exit of patients were recorded. 87 patients aged between 14 and 85 years were treated. The average age of the patients was 27.56. 72.4% of patients were female and 27.6% were male. The 98.9% of the patients took medication for suicidal purpose. Drugs used were analgesic, antidepressant, antipsychotic, anti-influenza, antibiotics, antiepileptics, and antihypertensives respectively. The non-drug substances that cause intoxication were organophosphate, wheat with rat poison, and cleaning chemicals. 46% of patients had taken antidepressant treatment before, and 4.6% of them had previously attempted suicide. An hour after the first exposure to the drug, 51.7% of patients were admitted to hospital. Only 50.6% of the patients received a single drug, whereas the rest received a large number of drugs. When they came to the intensive care, 81.6% of the patient's score had been identified as 15 in Glasgow. Two patients were in need of mechanical ventilation. 64.4% of patients were transferred to the service and 33.3% were discharged. Our mortality rate was 2.3 % and no mortality in women had been detected. Similar to the studies conducted in several centers, young women, who took drugs for suicidal purpose, constitute the majority of patients treated for intoxication in our intensive care unit. Analgesics and antidepressants were often used as drugs. Keywords: Intensive Care, Intoxication, Suicide
Abstract Objective Oxidative stress refers to an imbalance between reactive oxidative species and antioxidants. In this case-controlled, prospective, observational study, we investigated the total oxidant status, total antioxidant status, oxidative stress index, and albumin and C-reactive protein levels of children with cyanotic and acyanotic congenital heart diseases who had undergone on-pump cardiac surgery. Method The study groups consisted of 60 patients with congenital heart disease, who were operated under cardiopulmonary bypass, and a control group of 30 healthy individuals. The patients were classified into two groups. Among them, one was a patient group that consisted of 30 patients with acyanotic congenital heart disease and the other group consisted of 30 patients with cyanotic congenital heart disease. In the patient groups, blood samples were collected before surgery and at one and 24 hours following surgery. In control groups, blood samples were collected once during hospital admission. Results No statistically significant differences were found between the groups in terms of baseline total oxidant status, total antioxidant status, and oxidative stress index values. Regarding the postoperative first-hour and 24-hour total oxidant status and total antioxidant status levels as well as oxidative stress index values, there were no significant differences between the groups, except for an increase in total antioxidant status levels (p=0.002) 24 hours after surgery in cyanotic patients. Conclusion There was no difference between oxidative stress status of cyanotic and acyanotic congenital heart disease patients and healthy individuals. Oxidative stress status of cyanotic and acyanotic patients does not change after cardiac surgery under cardiopulmonary bypass.