Ulana Kotowski

Medical University of Vienna

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Gregor Heiduschka

Medical University of Vienna

Dietmar Thurnher

Medical University of Graz

Lorenz Kadletz

Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde

Sven Schneider

Medical University of Vienna

Isabella Stanisz

South Infirmary Victoria University Hospital

Rudolf Seemann

Medical University of Vienna

Markus Brunner

Universitätsklinikum Erlangen

Rainer Schmid

Medical University of Vienna

Boban M. Erović

Medical University of Vienna

Claudia Lill

Barmherzige Schwestern Krankenhaus Wien

Cooperative Institutions

Medical University of Vienna

Vienna General Hospital

University of Vienna

Comprehensive Cancer Center Vienna

Universitätsklinik für Hals-, Nasen- und Ohrenheilkunde

Universitätszahnklinik Wien

Christian Doppler Laboratory for Thermoelectricity

Evangelisches Krankenhaus Alsterdorf

Institute of Clinical Research

Barmherzige Schwestern Krankenhaus Wien

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

P25 Effect of bioactive compounds of zingiber officinale roscoe on head and neck tumor cell lines

Oral Oncology (2015)

Ulana Kotowski Gregor Heiduschka Sven Schneider E. Enzenhofer Isabella Stanisz

Zingiber officinale

Clonogenic assay

10.1016/j.oraloncology.2015.02.073

Cite

Citations (2)

MOESM2 of Quantitative proteome analysis of Merkel cell carcinoma cell lines using SILAC

Figshare (2019)

Ulana Kotowski Boban M. Erović Julia Schnöll Victoria Stanek Stefan Janik

Additional file 2: Table S1. Shows overlapping and specific proteins for each cell line.

Proteome

10.6084/m9.figshare.11406207

Cite

Citations (0)

ELMO3 expression indicates a poor prognosis in head and neck squamous cell carcinoma - a short report

Cellular Oncology (2016)

Lorenz Kadletz Gregor Heiduschka Robert Wiebringhaus Elisabeth Gurnhofer Ulana Kotowski

10.1007/s13402-016-0310-8

Cite

Citations (18)

Oral health status and dental care behaviours of head and neck cancer patients: a cross-sectional study in an Austrian tertiary hospital

Clinical Oral Investigations (2015)

Kristina Bertl Stefanie Loidl Ulana Kotowski Gregor Heiduschka Dietmar Thurnher

Cross-sectional study

Tertiary care

10.1007/s00784-015-1618-x

Cite

Citations (24)

Oral health status of patients after cancer treatment for squamous cell carcinoma in the upper aero-digestive tract (San Francisco)

Stefanie Loidl Kristina Bertl Ulana Kotowski Gregor Heiduschka Dietmar Thurnher

Objective Treatment for head & neck cancer is associated with severe oral complications, such as reduced salivary flow rate, mucositis, or development or exacerbation of oral diseases (caries and p ...

Digestive tract

Squamous cell cancer

Source

Cite

Citations (0)

Mcl-1 expression is up-regulated in malignancies of the parotid gland.

DOAJ (DOAJ: Directory of Open Access Journals) (2011)

Gregor Heiduschka Boban M. Erović Johannes Pammer Ulana Kotowski Alexandra Kaider

The anti-apoptotic protein Mcl-1 is highly expressed in various types of malignant tumors. Overexpression is reported to correlate with poor prognosis and disease progression. We report the expression levels of Mcl-1 in tumor samples of the parotid gland. A retrospective study containing 108 patients was performed. A tissue microarray of six malignancies of the parotid gland and pleomorphic adenoma as control was constructed. Parotid gland tumor samples were immunohistochemically stained for Mcl-1 and expression intensities were assessed. Statistical analysis included correlation to patients' clinical data and comparison of malignancies to the adenoma. All malignancies had significantly higher expression of Mcl-1 than the pleomorphic adenomas. The intensity, however, had no significant correlation to overall survival. Our immunohistochemical findings indicate that parotid gland malignancies produce high levels of Mcl-1 protein. Therefore, Mcl-1 might serve as a predictive co-marker in tumors of the parotid gland.

Tissue microarray

10.3233/dma-2011-0779

Cite

Citations (6)

Effect of the coffee ingredient cafestol on head and neck squamous cell carcinoma cell lines

Strahlentherapie und Onkologie (2015)

Ulana Kotowski Gregor Heiduschka Rudolf Seemann Julia Eckl‐Dorna Rainer Schmid

Clonogenic assay

10.1007/s00066-014-0807-x

Cite

Citations (17)

Role of cancer stem-cell marker doublecortin-like kinase 1 in head and neck squamous cell carcinoma

Oral Oncology (2017)

Lorenz Kadletz Dietmar Thurnher Robert Wiebringhaus Boban M. Erović Ulana Kotowski

10.1016/j.oraloncology.2017.02.007

Cite

Citations (16)

Effects of neratinib and combination with irradiation and chemotherapy in head and neck cancer cells

Oral Diseases (2016)

Sven Schneider Dietmar Thurnher Lorenz Kadletz Rudolf Seemann Markus Brunner

Prognosis of patients with head and neck squamous cell carcinoma (HNSCC) is still poor. Novel therapeutic approaches are of great interest to improve the effects of radiochemotherapy. We evaluated the effects of tyrosine kinase inhibitor neratinib on HNSCC cell lines CAL27, SCC25 and FaDu as a single agent and in combination with irradiation and chemotherapy.Effects of neratinib were evaluated in HNSCC cell lines CAL27, SCC25 and FaDu. Effect on cell viability of neratinib and combination with cisplatin and irradiation was measured using CCK-8 assays and clonogenic assays. Western blot analysis was performed to distinguish the effect on epithelial growth factor receptor and HER2 expression. Apoptosis was evaluated by flow cytometry analysis.Growth inhibition was achieved in all cell lines, whereas combination of cisplatin and neratinib showed greater inhibition than each agent alone. Apoptosis was induced in all cell lines. Combination of neratinib with irradiation or cisplatin showed significantly increased apoptosis. In clonogenic assays, significant growth inhibition was observed in all investigated cell lines.Neratinib, as a single agent or in combination with chemo-irradiation, may be a promising treatment option for patients with head and neck cancer.

Neratinib

10.1111/odi.12552

Cite

Citations (3)

Does Liquorice Root, Hawthorn Fruit and Chinese Plum Tea Improve Quality of Life in Head and Neck Cancer Patients after Primary or Adjuvant Radiotherapy? – A Randomized Double-blind Pilot Study

Trends in Oncology (2020)

Ulana Kotowski Muhammad Faisal Yan Ma Inamaria Erovic Boban M. Erovic

Objectives:Radiation induced side effects in head and neck cancers have life changing impact after treatment. We conducted a study to evaluate the effectiveness of traditional Chinese medicine tea in these patients. Methods: A randomized double-blinded pilot study was performed in head and neck cancer patients treated with radiotherapy. The study group received gargles of tea made from liquorice root, hawthorn fruit and Chinese plum. The quality of life was evaluated using the University of Washington Quality of life questionnaire Version 4 (UW-QOL). Results:The intervention group showed marginally significant outcome (p=0.075) in improved saliva production and reduced anxiety. Bitter taste was one of the major reasons for not continuing the trial. Conclusions:The proposed tea seems to provide a promising impact on the quality of life in head and neck cancer patients after adjuvant or primary radiotherapy. However, taste is a major concern and has to be adjusted to reduce patients´ dropout rate. Future trial with large samples are required to declare significant benefits.

Adjuvant radiotherapy

10.37155/2717-5278-0301-2

Cite

Citations (0)