Nor Aina E

Hospital Kuala Lumpur

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Ibrahim Naqiyah

National University of Malaysia

Sharifah Na

University Kebangsaan Malaysia Medical Centre

Ivyna Pau Ni Bong

Ministry of Health

M Rohaizak

National University of Malaysia

Noor H.A.

Z Zubaidah

Institute for Medical Research

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National University of Malaysia

University Kebangsaan Malaysia Medical Centre

Institute for Medical Research

Ministry of Health

University of Malaya

Institute for Medical Research

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National Cancer Patient Registry--Breast Cancer (NCPR-Breast Cancer).

PubMed (2008)

Nor Aina E

Breast cancer is the most common cancer in most part of the world and it is the most common cancer among Malaysian women. In order to estimate the overall survival and prognosis, it was decided that a National Cancer Patient Registry-Breast cancer be set up. It would be a tracking system form for breast cancer patients in Malaysia to help treatment outcomes. There would be useful for evaluating clinical management.

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Elevated Expression of CD151 Gene in Estrogen Receptor and Progesterone Receptor Positive Breast Carcinoma

Medicine & health (2011)

Ivyna Pau Ni Bong Z Zubaidah M Rohaizak Ibrahim Naqiyah Nor Aina E

Address for correspondence and reprint requests: Ivyna Bong Pau Ni, Hematology Unit, Cancer Research Centre, Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia. Tel: +603 2616 2724. Fax: +603 26162707. Email: ivyna@imr.gov.my Med & Health 2011; 6(1): 33-40 Ivyna Bong P.N. et al 34 transcriptase polymerase chain reaction (qRT-PCR) to measure the CD151 gene expression in 45 breast cancers. Our preliminary results revealed that CD151 expression is significantly higher in ER positive and PR positive breast cancers at 95% and 99% confidence intervals, respectively. In contrast, there is no significant correlation between CD151 expression and tumour grades or c-erbB-2 status at 95% confidence interval level. Our preliminary findings suggested that CD151 may be involved in the estrogen responsive pathways. CD151 could be a potential prognostic marker and therapeutic target in the treatment of estrogen dependent breast cancer patients.

Breast carcinoma

Hematology

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