Narendra Hulikal

Sri Venkateswara Institute of Medical Sciences

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Tekchand Kalawat

Sri Venkateswara Institute of Medical Sciences

Radhika Kottu

Sri Venkateswara Institute of Medical Sciences

Mutheeswaraiah Yootla

Sri Venkateswara Institute of Medical Sciences

Manilal Banoth

Sri Venkateswara Institute of Medical Sciences

Amit Kumar Chowhan

Sri Venkateswara Institute of Medical Sciences

Nandyala Rukmangadha

Sri Venkateswara Institute of Medical Sciences

Lakshmi Amancharla Yadagiri

Sri Venkateswara Institute of Medical Sciences

Ranadheer Manthri

Sri Venkateswara Institute of Medical Sciences

Usha Kalawat

Sri Venkateswara Institute of Medical Sciences

RanadheerGupta Manthri

Sri Venkateswara Institute of Medical Sciences

Cooperative Institutions

Sri Venkateswara Institute of Medical Sciences

153

Creative Commons

Tata Memorial Hospital

Kasturba Medical College, Manipal

Manipal Academy of Higher Education

Sri Venkateswara Veterinary University

All India Institute of Medical Sciences

Homi Bhabha National Institute

King's College London

All India Institute of Medical Sciences Raipur

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A Rare Case of Lower Limb Gangrene Following Anterior Exenteration in a Previously Irradiated Pelvis

Indian Journal of Gynecologic Oncology (2019)

Narendra Hulikal Bhavya Bayana Manilal Banoth Abha Chandra Andal Venkataraman

Gangrene

Pelvic exenteration

10.1007/s40944-019-0334-x

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Citations (0)

Nerve and vein preserving neck dissections for oral cancers: a prospective evaluation of spinal accessory nerve function and internal jugular vein patency following treatment

Acta Otorhinolaryngologica Italica (2018)

G. Rajashekhar Reddy Narendra Hulikal A.Y. Lakshmi B Vengamma

Nerve and vein preserving modification of the radical neck dissection is commonly used in the management of oral squamous cell cancers. There is limited literature addressing nerve function and vein patency following treatment. We prospectively analysed 65 patients with nerve conduction study using surface electromyography at baseline, 1 month and 6 months post-surgery and colour Doppler of the internal jugular vein at baseline and 1 month post-surgery. We also studied functional outcomes of nerve sparing with arm abduction test and Neck Dissection Quality of Life questionnaire. There was a statistically significant increase in mean latency of motor action potential and decrease in the mean amplitude of the motor action potential following surgery, suggesting nerve dysfunction. Following surgery, there was a significant decrease in the diameter of the vein as well as an increase in the velocity of blood flow; there was partial thrombus in 5% of individuals. In conclusion, even though nerve dysfunction compromised shoulder abduction, vein dysfunction rarely resulted in any significant clinical impact.Preservazione del nervo accessorio spinale e della vena giugulare interna durante dissezione del collo per carcinoma del cavo orale: valutazione prospettica della funzione del nervo e della pervietà della vena dopo trattamento.La preservazione del nervo accessorio spinale e della vena giugulare interna durante la dissezione del collo è una pratica comune nella gestione del carcinoma squamoso del cavo orale. Tuttavia, la letteratura riguardante la funzione del nervo e la pervietà della vena è limitata. Pertanto, abbiamo analizzato retrospettivamente 65 pazienti e abbiamo studiato tramite elettromiografia superficiale la funzione del nervo spinale basale e dopo 1 mese e dopo 6 mesi dall’intervento e tramite color doppler la pervietà della vena giugulare interna basale e dopo 1 mese dall’intervento. Abbiamo inoltre studiato i risultati funzionali mediante il test di abduzione del braccio e il questionario “Neck dissection Quality Of Life”. È risultato un aumento statisticamente significativo della latenza media del potenziale d’azione motorio e un decremento dell’ampiezza media del potenziale d’azione motorio in seguito a trattamento chirurgico, suggerendo quindi una disfunzione del nervo. Inoltre, in seguito all’intervento, c’è stato un decremento altrettanto significativo del diametro della ven, e, parallelamente, un incremento della velocità del flusso sanguigno e nel 5% dei pazienti è stata documentata una trombosi parziale. In conclusione, da una parte la disfunzione nervosa ha compromesso il movimento di abduzione del braccio, dall’altra la disfunzione venosa raramente ha avuto un impatto clinico.

Accessory nerve

Internal jugular vein

Neck dissection

10.14639/0392-100x-1481

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Citations (1)

Incidental Intraoperative Discovery of Colonic Growth in a Patient with Esophageal Carcinoma– Lessons Learnt!

Indian Journal of Surgery (2012)

Narendra Hulikal Rohan Vinayak Joseph Thomas

Cardiothoracic surgery

Presentation (obstetrics)

10.1007/s12262-012-0687-1

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Citations (1)

The Importance of Comprehensive Surgical Staging Including Para-Aortic Lymph Node Dissection of Presumed Early Stage Epithelial Ovarian Cancer: A Contemporary Prospective Evaluation

Journal of Gynecologic Surgery (2017)

Ramana Reddy Naru Narendra Hulikal Rukmangadha Nandyal Vijayalkshmidevi Bodagala

Objective: It is the conventional belief that comprehensive staging of presumed early ovarian cancer results in upstaging of the disease in ∼30% of patients. With the latest developments in modern technology and wider use of diagnostic imaging, the importance of such surgical staging needed prospective evaluation. Materials and Methods: This was a prospective cohort study. It was conducted in a tertiary cancer hospital over a period of 18 months, starting in June 2014. All willing women with clinically suspected early stage epithelial ovarian cancer, based on preoperative contrast-enhanced computerized tomography of the abdomen and pelvis and serum CA-125 levels, were included. At laparotomy, the diseased ovary was removed from each patient and sent for frozen- section confirmation for epithelial cancer. Patients with confirmation of epithelial cancer underwent comprehensive surgical staging, including systematic pelvic and para-aortic lymph node dissection (PAND) as prescribed by the International Federation of Gynecology and Obstetrics. Results: A total of 42 patients underwent complete surgical staging, of whom 4 were excluded at final analysis. On comprehensive staging, the disease was upstaged in 8 (21%) patients: 4 had retroperitoneal nodal metastases (11%); 2 had paracolic peritoneal involvement (5%); and 2 patients had omental involvement (5%). A mean of 16 pelvic and 13.76 para-aortic nodes were removed. The para-aortic nodes were involved in 3 (75%) of the 4 patients with retroperitoneal nodal involvement. Of the parameters analyzed, no statistically significant factors were found that could have predicted the lymph nodal involvement. Conclusions: Comprehensive staging, including systematic PAND, is still the “gold standard” in the management of early stage ovarian cancer. (J GYNECOL SURG 33:184)

10.1089/gyn.2017.0022

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Citations (1)

Guide-wire embolism during subclavian vein catheterization by Seldinger technique

Indian Journal of Critical Care Medicine (2006)

Narendra Hulikal K. R. Baghavan

Percutaneous cannulation of central veins by Seldinger technique is a popular approach in intensive care settings. We report a case of embolization of a complete guide-wire during such a procedure. Our case differs from the few earlier reported cases in that subclavian vein was the entry site. While reviewing the available literature, we discuss few reasons and management of such a mishap.

Subclavian vein

10.4103/0972-5229.29846

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Citations (9)

Utility of 18F-FDG PET/CT in Management of Pancreatic and Periampullary Masses—Prospective Study from a Tertiary Care Center

Indian Journal of Surgical Oncology (2021)

Chandra Teja Reddy S Krishna Mohan V. S Sai Moulika Jeepalem Ranadheer Manthri Tekchand Kalawat

Periampullary cancer

Surgical oncology

Pancreatic mass

PET-CT

10.1007/s13193-021-01434-1

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Citations (1)

Primary Large Cell Neuroendocrine Carcinoma of the Ovary: A Case Report and Review of the Literature

Clinics in Oncology (2017)

Naru Ramana Reddy Vemula Venkata Vijaya Laxmi Haranadh Harsha Amit Kumar Chowhan Narendra Hulikal

Neuroendocrine carcinoma

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Drain Versus No-Drain in Patients After Surgery for Early Stage Gynecologic Malignancies: A Randomized Controlled Study

Journal of Gynecologic Surgery (2022)

Ragavendra Naik Sivanath Reddy Gajjala Manilal Banoth Narendra Hulikal

Objective: This study compared rates of postoperative complications in patients, with early stage gynecologic malignancies, who had drains or no drains used after bilateral pelvic lymph node dissections (PLNDs), with or without para-aortic lymph-node dissections (LNDs). Materials and Methods: All willing patients, ages 18–70, with histologically proven gynecologic malignancies, who had PLNDs, with or without para-aortic LNDs, as a part of their primary surgeries, were randomized to have drains inserted or no drains inserted post surgery. Intraoperative details as well as postoperative length of drainage, hospital stays, and morbidity (wound complications, fluid accumulation needing intervention, hematomas, seromas, and lymphocysts) were noted. Patients were followed in 30 days post surgery, clinically and radiologically, to evaluate and compare morbidity in both groups. Results: A total of 144 cases were studied (73 in a drain group and 71 in a no-drain group). The average visual analogue score for pain was 6.7 in the drain group and 6.6 in the no-drain group (p = 0.44). The average postoperative hospital stay was 7 days in the drain group and 6 days in the no-drain, group (p = 0.014). There was no significant difference in other parameters (wound-infections, fluid accumulation needing intervention, seromas, lymphocysts, and paralytic ileus). Conclusions: Placing pelvic drains following surgeries routinely for early-stage gynecologic malignancies needs to be revisited as it confers no advantage, and by avoiding drains, patients can be discharged to go home earlier. (J GYNECOL SURG 38:354)

Ileus

10.1089/gyn.2022.0002

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Citations (1)

Value of cytokeratin-19, Hector Battifora mesothelial-1 and galectin-3 immunostaining in the diagnosis of thyroid neoplasms

Journal of Laboratory Physicians (2018)

Sanuveda Rajasekhar Nandyala Rukmangadha Amit Kumar Chowhan Phaneendra Bobbidi Mutheeswariah Yootla

Diagnosis of types and aggressiveness of thyroid cancers is difficult. The "gold standard" in diagnosis is using routine hematoxylin and eosin staining. Several markers have been investigated for differentiating them among which cytokeratin-19 (CK-19), Hector Battifora mesothelial cell (HBME-1), and galectin-3 are found to be most commonly used. Most studies have evaluated the single expression of markers in various thyroid lesions.To know the value of immunohistochemical expression of CK-19, HBME-1, and galectin-3 in diagnosing thyroid neoplasms. To study the expression and compare the results of HBME-1, CK-19, and galectin-3 immunohistochemical markers in histopathologically diagnosed malignant lesions and nonmalignant lesions and demonstrate their usefulness in differentiating them.A prospective study was carried out on thyroidectomy specimens sent in 10% buffered formalin to Department of Pathology, SVIMS, Tirupati, from May 2013 to August 2014. Sensitivity and specificity for each marker and their combination in diagnosis were calculated.Among 120 cases, nonmalignant lesions were 70 (58.33%) and malignant lesions 50 (41.67%). Among nonmalignant lesions, 65 (93%) were adenomatous goiter and 5 (7%) were follicular adenomas. In malignant lesions, 48 (96%) were papillary carcinoma and 1 (2%) each of follicular carcinoma and anaplastic carcinoma. Among papillary carcinomas, classical were 26 (54.16%) followed by 17 follicular variant (35.41%). Galectin-3 had highest sensitivity of 90% and HBME-1 had highest specificity of 97.14%.Panel of HBME-1+ galectin-3 or CK-19, HBME-1, and galectin-3 increase the accuracy of diagnosis in histopathologically difficult cases.

Galectin-3

Immunostaining

10.4103/jlp.jlp_106_17

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Citations (9)

Association of single nucleotide polymorphisms of adiponectin and leptin genes with breast cancer

Molecular Biology Reports (2019)

Sarvari Geriki Aparna R. Bitla P Srinivasarao Narendra Hulikal Mutheeswaraiah Yootla

10.1007/s11033-019-05070-5

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Citations (5)