Georgiev Gp

Institute of Gene Biology

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Co-Authors

Lukanidin Em

Institute of Gene Biology

АП

А. П. Рысков

Institute of Gene Biology

СЛ

С. Л. Киселев

Vavilov Institute of General Genetics

Sergey V. Razin

Institute of Gene Biology

Mant'eva Vl

Gnuchev Nv

Zbarskiĭ Ib

Koltzov Institute of Developmental Biology

Larin Ss

Russian Academy of Sciences

Samarina Op

National Institutes of Health

Grigori Enikolopov

Stony Brook University

Cooperative Institutions

Russian Academy of Sciences

Institute of Gene Biology

Lomonosov Moscow State University

Ministry of Health of the Russian Federation

Koltzov Institute of Developmental Biology

Institute of Oncology NN Petrov

Institute of Molecular Genetics

Engelhardt Institute of Molecular Biology

Moscow State University

Czech Academy of Sciences, Institute of Molecular Genetics

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[Inhibitory receptors of lymphocytes and their role in antitumor immunity].

PubMed (2007)

Zakeeva Ir Berezhnoĭ Ae Gnuchev Nv Georgiev Gp Lapin Ss

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Citations (1)

[The structure of nuclear pre-mRNA. VII. The hybridization and renaturation properties of double-stranded sequences of nuclear pre-mRNA].

PubMed (1975)

А. П. Рысков Kramerov Da Limborskaia Sa Georgiev Gp

Some properties of the double-stranded regions of pre-mRNA are discribed. 1. The double-stranded regions contain approximately 80 base pairs. 2. The material contains the heterogeneous populations of sequences and some homogenous material which renatures with a COT1/2 value of (1.5-3) X 10(-4). 3. Identical sequences of fast-renaturing "hairpins" may be found in various tissues. 4. Double-stranded RNA and mRNA have some sequences complementary to each other. These results consistent with the view that the hairpin sequences may act as specific recognition sites for ribonucleases involved in processing of pre-mRNA.

Double stranded

Precursor mRNA

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Citations (3)

[Marked inhibition of transcription in mammalian cells by x-rays during disturbance of the topological continuity of superhelical DNA loops].

PubMed (1987)

Luchnik An Dubinina En Zbarskiĭ Ib Georgiev Gp

Transcription

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Citations (1)

[Melanoma cell lines as the basis for antitumor vaccine preparation].

PubMed (2005)

Mikhaĭlova In Lukashina Mi Baryshnikov AIu Morozova Lf Burova Os

The aim of the study was to obtain cell lines from tumor samples, and to determine phenotypic cell characteristics in order to choose the optimal line for vaccine preparation. 15 cell lines with stable growth, varying in cultural growth character and cytomorphology, were obtained from samples taken from patients with metastatic skin melanoma. Immunofluorescense method was used to determine the expression of T- and B-lymphocyte markers, antigens of major histocompatibility complex (MHC) class I and II, and CD86 co-stimulating molecule in the cell lines. The expression of melanocyte differentiation antigens and cancer/testicular antigens was evaluated using immunocytochemical assay. The results allowed the authors to distinguish three types of melanoma cell lines according to the expression of MHC molecules: MHC-negative; MHC class I positive; MHC classes I and II positive.

MHC restriction

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Citations (19)

[Presence of histone H1 in the chromosome of virion SV-40 isolated from the nuclei of infected cells].

PubMed (1978)

Nedospasov Sa Bakaev Vv Georgiev Gp

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[Cloning genes, specifically expressed in the cerebral cortex and cerebellum of adult rats].

PubMed (1996)

Akopian An Chestkov Av Baka Id Bukhman Vl Georgiev Gp

To isolate genes differentially expressed in the rat brain cortex and cerebellum, a subtractive cDNA cloning procedure requiring only small quantities of poly(A+) RNA, followed by differential screening, was used. Two novel genes, MK and 3L7, with cortex- and cerebellum-specific expression were identified. These genes displayed different expression patterns in the brain cortex, cerebellum, and hippocampus during postnatal development.

Cloning (programming)

Suppression subtractive hybridization

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[Molecular mechanism of transposition memory in the mdg4-locus cut system of Drosophila melanogaster].

PubMed (1985)

Mirzokhi LIu Priĭmiagi Af Il'in IuV Gerasimova Ti Georgiev Gp

Transposition (logic)

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[Use of genetically modified embryonic stem cells for creating transgenic animals].

PubMed (2004)

Pryzhkova Mv Zakeeva Ir Kibardin Av Georgiev Gp С. Л. Киселев

Targeted genetic modification of embryonic stem cells (ESC) was used to obtain nondifferentiated cell clones containing the foreign genetic material in the genome. It was demonstrated that transgenic animals may be obtained by ESC injection in preimplantation embryos and subsequent transplantation of the embryos into a recipient female. Using this method, we constructed chimeric animals with a modified genome.

Chimera (genetics)

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[Primary structure of the repeating element B2 and of the adjoining sequences in cloned mRNA actively transcribing in mouse liver cells].

PubMed (1983)

Ivanov Pl А. П. Рысков Kramerov Da Georgiev Gp

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The structure of nuclear D-RNA. 3. Nature and hybridization properties of 5'-terminal sequences.

PubMed (1972)

А. П. Рысков Farashyan Vr Georgiev Gp

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