Metabolic syndrome is most commonly caused by improper, irregular diet, and physical inactivity. However, sometimes the treatment approach to metabolic syndrome is not easy, and if a patient with a low calorie diet and physical activity does not lose weight, other underlying diseases need to be suspected. A sixty-seven year old patient with metabolic syndrome is presented (obesity, accumulation of fat in the abdomen, glucose intolerance, dyslipidemia, and hypertension), who’s attempts at reduction diets and physical activity caused a strong feeling of hunger, general weakness and nausea ; these symptoms were reduced after food intake. Having had a haematemesis (vomiting blood) the patient was admitted to the department of gastroenterology. Examination indicated hiatal hernia (a shift of the upper part of the stomach into the chest through the diaphragm) and chronic gastritis, and for established hypoglycemia with glucose 1.5 to 2.6 mmol/l. The patient was transferred to the department of endocrinology. Additional endocrinologic investigations found insulinoma, a pancreatic tumor sized 0.9 cm. The patient refused surgery and was treated with medication, receiving diazoxide tablets. After two years she had a proper body weight and had no signs of metabolic disorders, and computed tomography of the abdomen showed a significant decrease in pancreatic tumor size. Therefore, in patients with metabolic syndrome in which low calorie diet and physical activity does not reduce body weight, or if they have associated symptoms, endocrinological treatment should be conducted.
Pregnant women experience a set of biological and psychological disturbances. The aim of this study was to assess the appearance of depressive symptoms and suicidal thoughts in pregnant women during the third trimester of pregnancy.A total of 110 pregnant women were included in the study. All of them filled out an anonymous questionnaire about sociodemographic data, Edinburgh Postnatal Depression Scale (EPDS), Beck Depression Inventory (BDI), and Beck Anxiety Inventory (BAI).Study participants were between 18-46 years of age. 45.45% of the pregnant women were between 37 and 39 weeks pregnant. According to the EPDS, the risk for perinatal depression was observed in 29 (23.36%) pregnant women: 15 (13.64%) of them had a total score on EPDS from 10-12, and 14 (12.72%) had a total score of 13-20. A higher score on both Beck scales was characteristic for pregnant women with a higher risk for the development of perinatal depression based on the results on EPDS. The prevalence of suicidal thoughts was 2.73%.Perinatal depression is a state which should be given more attention. The recognition of perinatal depression during pregnancy allows health medical workers to observe pregnant women at risk and then to make preventive and clinical interventions. The risk for perinatal depression is higher in pregnant women with more expressed depressive and anxiety symptoms. Pregnant women with suicidal thoughts are more anxious and depressed.
Paradoxal reactions to benzodiazepines may be presented in different ways. In some persons, primarily older persons and children, especilally with coexisting somatic disorders, paradoxal reactions may be manifested as logoroic speech, unapropriate social behaviour, and psychomotor agitation. Although benzodiazepines lower levels of agression, few studies described that in some persons levels of agression get higher with use of benzodiazepines. From our clinical practice we will present the patient who deveoped changed 'uninhibited' behavour after use of alprazolam perorally. Patient K.M. in age of 41 years, married, with one child, works as a clark at office. He denied psychiatric disoreders in his relatives, and also he denied any somatic disorders. Patient came to the psychiatrist after he had troubles at his job, he was acused of something he didn't do. He desided to ask help after few weeks of troubles in functioning, he couldn't sleep, he was anxious, emotionally instable, he couldn't controll crying, his thougts were peocupaied with problems at job, his communication with his family was disturbed. His wife told him to seek for help. He was diagnsed as Acute reaction to stress, and prescribed alprazolam in small dose od 2x0,25 mg per day. After two weeks he came to controll and described the same symptoms, so his therapy was corrected to alprazolam 3x0,5mg per day. After ten days he came with his wife to controll exam. He was different person as his wife described him. He was angry all the time, he was verbally agressive to family members as well as to their friends. He described that he couldn't keep his mouth quiet, everything that bothered him he yelled about it. He went to his job and was verbally agressive and abusive to his working collleagues. Patient described very high levels of agitation, he couldn't be still at one place. Before his wife described him as very quiet and nice person, he never raised his voice, and always found peacefull solutions to every problem. We told him to stop taking the medication, and he came to controll exam after one week. Two days after the last medication his agression dissapeared, he was ashamed of his behaviour. But he told that lot's of things he sad last few weeks he wanted to say for many years before, but he was too anxious and affraid to do so. Therefore, in this case report it is unclear what really happened, was that desinhibition or not?
Analizirajući relevantna istraživanja shvaćanja međudjelovanja okolišnih kulturnih i socioekonomskih čimbenika na zdravstveno stanje te daljnjim proučavanjem dostupne literature dolazimo do širine i jednostavnosti definiranja pojmova bolesti i kriznoga stanja. Shvaćanje bolesti i suočavanje s njom uvijek je individualno, što uporište pronalazi u vlastitoj predodžbi bolesti. Krizno stanje označava poremećaj psihosocijalne ravnoteže koji je posljedica nekoga nepovoljnoga događaja ili prolongiranih, često dugotrajnih, nepovoljnih životnih okolnosti. Cilj je ovoga preglednoga rada pojasniti osnovne elemente koji doprinose stvaranju percepcije bolesti i kriznoga stanja pacijenta te važnost empatije terapeuta tijekom sudjelovanja u liječenju pacijenata, što podrazumijeva stvarno dijeljenje osjećaja tereta, uz zadržavanje profesionalne objektivnosti i kontroliranja terapijskoga plana.