This is a survey of the French South-East Group of Research in Pediatric Surgery (GRECPSE) concerning 18 Solid Adrenal Tumors, observed during a 20-years period (1969-1989) in 11 boys and 8 girls. 13 are tumors of the adrenal cortex (9 adenomas and 4 carcinomas). Clinical virilization is found in 7, cushing's syndrome in 3; while feminizing tumor, Conn's syndrome and non hormone-secreting form are quite exceptional (1 case each, respectively). 5 are adrenal pheochromocytomas (4 benign tumors and 1 malignant with local invasion). Ultrasonography, CT Scan and MIBG Scintigraphy are modern procedures which permit localization of the small and non palpable tumors with high accuracy. They make easier surgical management. Differentiation between benign and malignant tumors of the adrenal glands still remains the main problem. The course of the disease is surely the only distinguishing parameter. However weight tumor and selective histopathological characteristics are useful in predicting the prognosis and behavior of such tumors = Mitotic activity for adrenocortical tumors, extensive areas of necrosis and small cells for pheochromocytomas have the highest discriminating value.
BACKGROUND Nonablative remodeling has been recently proposed as an alternative to CO2 and Er:YAG resurfacing. OBJECTIVE To evaluate the efficacy and safety of a 1540 nm Er:glass laser with contact cooling in nonablative skin remodeling, focused on perioral and periorbital rhytides. METHODS Sixty patients (mean age 47 years), Fitzpatrick skin types I–IV were treated four times over 6-week intervals. Patients were evaluated using digital photographs, histology, ultrasound imaging, and profilometry with silicone imprints in order to quantitate the degree of clinical improvement. RESULTS All subjects reported subjective improvement in the quality and visual aspect of their skin. This was confirmed by a 40.2% reduction of anisotropy (P < .001) 6 weeks after the fourth treatment. Ultrasound imaging demonstrated a 17% increase of dermis thickness (P < .005). Biopsy specimens showed evidence of new collagen formation. CONCLUSION This study has clearly demonstrated that irradiation with 1540 nm Er:glass laser can lead to new collagen formation, dermis thickening, reduction of anisotropy of the skin, and clinical improvements. The lack of adverse effects confirmed that this 1540 nm laser emitting in a pulsed mode coupled with an efficient cooling system is safe.
Journal Article Malignant melanoma occurring on a 'naevus on naevus' Get access B. Guillot, B. Guillot Service du Dermatologie‐Phlebologie. Hôpital Saint Charles, Service d'Anatomo Pathologie, Gui de Chauliac, CHU, 34059 Montpelier, France Search for other works by this author on: Oxford Academic Google Scholar D. Bessis, D. Bessis Service du Dermatologie‐Phlebologie. Hôpital Saint Charles, Service d'Anatomo Pathologie, Gui de Chauliac, CHU, 34059 Montpelier, France Search for other works by this author on: Oxford Academic Google Scholar G. Barneon, G. Barneon Service du Dermatologie‐Phlebologie. Hôpital Saint Charles, Service d'Anatomo Pathologie, Gui de Chauliac, CHU, 34059 Montpelier, France Search for other works by this author on: Oxford Academic Google Scholar S. Monpoint, S. Monpoint Service du Dermatologie‐Phlebologie. Hôpital Saint Charles, Service d'Anatomo Pathologie, Gui de Chauliac, CHU, 34059 Montpelier, France Search for other works by this author on: Oxford Academic Google Scholar J.J. Guilhou J.J. Guilhou Service du Dermatologie‐Phlebologie. Hôpital Saint Charles, Service d'Anatomo Pathologie, Gui de Chauliac, CHU, 34059 Montpelier, France Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 124, Issue 6, 1 June 1991, Pages 610–611, https://doi.org/10.1111/j.1365-2133.1991.tb04962.x Published: 01 June 1991
We report the emergence of polyclonal expansion of gut lymphocyte associated tissues producing IgA in a patient with rheumatoid arthritis associated with a high serum IgA concentration. The role of IgA in rheumatoid arthritis is reviewed.
