Bruno Rustum Andréa

Hospital Universitário Pedro Ernesto

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Co-Authors

Márcio Galindo Kiuchi

Royal Perth Hospital

Jocemir Ronaldo Lugon

Universidade Federal Fluminense

Maria Angela Magalhães de Queiroz Carreira

Universidade Federal Fluminense

Shaojie Chen

Affiliated Hospital of Guizhou Medical University

Tetsuaki Kiuchi

Hospital Pró-Cardíaco

Miguel Luis Graciano

Universidade Federal Fluminense

Philipp Sommer

Heart and Diabetes Center North Rhine-Westphalia

Gerhard Hindricks

Leipzig Heart Institute

Simone Farah

Universidade do Estado do Rio de Janeiro

Shaojie Chen

Universitätsmedizin Greifswald

Cooperative Institutions

Leipzig Heart Institute

Leipzig University

Deutsches Herzzentrum der Charité

Istituti di Ricovero e Cura a Carattere Scientifico

Universidade do Estado do Rio de Janeiro

Universidade Federal do Rio de Janeiro

University of Florence

Azienda Ospedaliero-Universitaria Careggi

Gruppo Italiano per il Trapianto di Midollo Osseo

Hospital Universitário Clementino Fraga Filho

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Outcome of patients activating an unrelated donor search: the impact of transplant with reduced-intensity conditioning in a large cohort of consecutive high-risk patients

Alessandro Rambaldi Bruno Rustum Andréa R Fanin Fabio Ciceri Francesca Bonifazi

Intensity

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BAV avançado e taquiarritmia sustentada do tipo Torsades de Pointes: registro ambulatorial de 24 horas

Rev. SOCERJ (2008)

Martha Demétrio Rustum Elaine Mansur Bruno Rustum Andréa

Torsades de pointes

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Gli artigiani nascosti del cinema. I rumoristi e la produzione di effetti sonori negli anni ’60 e ’70

Quaderni del CSCI: rivista annuale di cinema italiano (2019)

Ilario Meandri Bruno Rustum Andréa

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Efficacy evaluation of renal denervation with a standard irrigated cardiac ablation catheter in a 44 years old male with refractory hypertension: a case report

Journal of the American Society of Hypertension (2015)

L COSTA Valério Fuks João Otávio de Queiroz Araujo Francisco Chamié João Addson

White coat hypertension

Refractory (planetary science)

Masked Hypertension

10.1016/j.jash.2015.03.086

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Telecardiology on the Diagnostic Support of Chest Pain in Twenty-Two Emergency Care Units (UPA 24h) in The State of Rio de Janeiro

Figshare (2019)

Simone Farah Bruno Rustum Andréa Rogério Casemiro Da Silva Alexandra Monteiro

Abstract Background: Telecardiology may be a useful support in diagnosis and management of chest pain. Objective: Evaluate the application of telecardiology to support the differential diagnosis of chest pain in patients admitted to Emergency Care Units. Method: Observational, retrospective and documental study of 5,816 patients admitted with supposedly cardiological chest pain in twenty two Emergency Care Units in the state of Rio de Janeiro. Data were tabulated and analyzed by Excel® software, using simple descriptive statistics, from the database of the Cardiology Consultancy Nucleus. Results: Diagnostic disagreement was found in 1,593 (27.39%) cases. Of these, 1,477 (92.72%) were diagnosed locally as non-ST-elevation myocardial infarction (non-STEMI), 74 (4.64%) as acute myocardial infarction with ST-segment elevation (STEMI), 40 (2.52%) as acute pulmonary edema (APE) and 2 (0.12%) as tachyarrhythmia. Intensive care referral was requested to 100% of these patients. After telecardiology, the diagnoses were: 385 (24.17%) unstable angina, 289 (18.14%) congestive heart failure, 212 (13.31%) APE, 174 (10.92%) STEMI, 152 (9.54%) hypertensive emergency, 113 (7.09%) acute chronic renal failure, 89 (5.59%) non-STEMI, 89 (5.59%) pneumonia, 39 (2.45%) sepsis, 26 (1.63 %) myopericarditis, 20 (1.26%) tachyarrhythmia and 5 (0.31%) orovalvar disease. The outcome after telecardiology was 1,178 discharges (73.94%), 338 (21.21%) referrals, 62 (3.90%) deaths and 15 (0.95%) unknown. Conclusion: Telecardiology was effective in chest pain diagnosis and management, optimizing hospital admission in the public health system.

10.6084/m9.figshare.7865975

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Impact of Catheter Ablation on Quality of Life in Patients with Atrial Fibrillation

Journal of Cardiovascular Electrophysiology (2011)

Bruno Rustum Andréa Gerhard Hindricks

Cardiac Electrophysiology

Editorial board

10.1111/j.1540-8167.2011.02214.x

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Citations (3)

Cardiac pacing strategies and post-implantation risk of atrial fibrillation and heart failure events in sinus node dysfunction patients: a collaborative analysis of over 6000 patients

Clinical Research in Cardiology (2016)

Shaojie Chen Zhenglong Wang Márcio Galindo Kiuchi Bruno Rustum Andréa Mitchell W. Krucoff

Clinical endpoint

Sick sinus syndrome

10.1007/s00392-016-0973-1

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Citations (6)

Association of Preoperative Renin-Angiotensin System Inhibitors With Prevention of Postoperative Atrial Fibrillation and Adverse Events

JAMA Network Open (2019)

Shaojie Chen Willem-Jan Acou Márcio Galindo Kiuchi Christian Meyer Philipp Sommer

Importance

Postoperative atrial fibrillation (POAF) is a well-known complication after cardiac surgery. Renin-angiotensin system inhibitors (RASIs) have been suggested as an upstream therapy for selected patients with AF; however, evidence in the surgical setting is limited.

Objective

To evaluate the role of preoperative RASIs in prevention of POAF and adverse events for patients undergoing cardiac surgery.

Data Sources

The PubMed database and the Cochrane Library from inception until December 31, 2018, were searched by using the keywordsrenin-angiotensin system inhibitorsORangiotensin-converting enzyme inhibitorsORangiotensin receptor blockerORaldosterone antagonistANDcardiac surgery. ClinicalTrials.gov was searched from inception until December 31, 2018, by using the keywordspostoperative atrial fibrillation.

Study Selection

Randomized clinical trials (RCTs) and observational studies comparing the association between preoperative RASI treatment vs no preoperative RASI treatment (control group) and the incidence of POAF were identified. Eleven unique studies met the selection criteria.

Data Extraction and Synthesis

Pooled analysis was performed using a random-effects model. Sensitivity and subgroup analyses of RCTs were performed to test the stability of the overall effect. Metaregression was conducted to explore potential risk of bias.

Main Outcomes and Measures

The primary outcome was POAF, and the secondary outcomes included rates of stroke and mortality and duration of hospitalization.

Results

Eleven unique studies involving 27 885 unique patients (74.4% male; median age, 65 years [range, 58.5-74.5 years]) were included. Compared with the control group, the RASI group did not have a significantly reduced risk of POAF (odds ratio [OR], 1.04; 95% CI, 0.91-1.19;P = .55;z = 0.60), stroke (OR, 0.86; 95% CI, 0.62-1.19;P = .37;z = 0.90; without significant heterogeneity,P = .11), death (OR, 1.07; 95% CI, 0.85-1.35;P = .56;z = 0.59; without significant heterogeneity,P = .12), composite adverse cardiac events (OR, 1.04; 95% CI, 0.91-1.18;P = .58;z = 0.56), or a reduced hospital stay (weighted mean difference, −0.04; 95% CI, −1.05 to 0.98;P = .94;z = 0.07) using a random-effects model. Pooled analysis focusing on RCTs showed consistent results. The primary overall effect was maintained in sensitivity and subgroup analyses. Metaregression showed that male sex was significantly associated with POAF (τ² = 0.0065;z = 3.47;Q = 12.047;P < .001) and that use of β-blockers was associated with a significantly reduced risk in developing POAF (τ² = 0.018;z = −2.24;Q = 5.0091;P = .03).

Conclusions and Relevance

The findings from this study suggest that preoperative RASI treatment does not offer additional benefit in reducing the risk of POAF, stroke, death, and hospitalization in the setting of cardiac surgery. The results provide no support for conventional use of RASIs for the possible prevention of POAF and adverse events in patients undergoing cardiac surgery; further randomized data, particularly among those patients with heart failure, are needed.

Candesartan

10.1001/jamanetworkopen.2019.4934

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Citations (18)

Telecardiology on the Diagnostic Support of Chest Pain in Twenty-Two Emergency Care Units (UPA 24h) in The State of Rio de Janeiro

Figshare (2019)

Simone Farah Bruno Rustum Andréa Rogério Casemiro Da Silva Alexandra Monteiro

10.6084/m9.figshare.7678034

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Citations (0)

Renal Sympathetic Denervation in Patients With Hypertension and Chronic Kidney Disease: Does Improvement in Renal Function Follow Blood Pressure Control?

Journal of Clinical Hypertension (2014)

Márcio Galindo Kiuchi Shaojie Chen Bruno Rustum Andréa Tetsuaki Kiuchi Maria Angela Magalhães de Queiroz Carreira

Twenty‐seven patients with resistant hypertension and chronic kidney disease were treated by renal sympathetic denervation (RSD) and followed for 12 months. Patients were retrospectively divided into controlled and uncontrolled blood pressure (BP) groups. Increases in mean estimated glomerular filtration rate ( eGFR ) were found at months 1, 3, 6, and 12 in the controlled group ( P <.0001, for every time point). The mean change in eGFR after 12 months was 18.54±8.15 mL /min/1.73m 2 higher in the controlled group ( P =.0318). In patients in the controlled group with baseline eGFR <45 mL /min/1.73 m 2 , responders (with an increase in eGFR >6.2%) corresponded to 50% at 6 months and 83% at 12 months. In the patients with baseline eGFR ≥45 mL /min/1.73 m 2 , all patients were labeled as responders at months 6 and 12. Median albumin:creatinine ratio after 12 months was lower than baseline only in the controlled group ( P =.0003). Our results suggest that patients with this profile who reached BP control by RSD also experienced a significant improvement in renal function.

Renal sympathetic denervation

10.1111/jch.12415

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Citations (25)