Gaia Claudia Viviana Viola

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Air pollution biological effects in children living in Lecce (Italy) by Buccal micronucleus cytome assay (the MAPEC_LIFE study)

International Journal of Sustainable Development and Planning (2016)

Antonio De Donno Tiziana Grassi Elisabetta Ceretti Gaia Claudia Viviana Viola Sara Levorato

The aim of the MAPEC_LIFE (Monitoring Air Pollution Effects on Children for Supporting Public Health Policy) study is to evaluate the associations between the concentrations of air pollutants and early biological effects in children living in five Italian towns (Brescia, Torino, Lecce, Perugia and Pisa) characterised by varying levels of air pollution.This paper presents the results of micronucleus cytome assays performed on the oral mucosa cells of subjects living in Lecce (Puglia, Italy) and their relationship to factors associated with indoor/outdoor exposure and lifestyles.The study was conducted on 6-8-year-old schoolchildren living in Lecce.The micronucleus cytome assay was performed on exfoliated buccal cells collected from the oral mucosa of children using a soft-bristled toothbrush.Micronuclei were evaluated only in normal differentiated cells.Overall, 43.0% of the samples tested were positive, with an average frequency of 0.28 MN/1000 differentiated cells.Data analysis shows positive associations between the frequency of MN in the children's buccal mucosa cells and obesity, heavy traffic and smoking mothers, while outdoor sports seem to have the opposite effect.These data will be integrated with data from the other cities involved in the MAPEC_LIFE study and could be used to build a model for estimating global genotoxic risk.

Buccal swab

Buccal mucosa

10.2495/sdp-v11-n4-500-510

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Evaluation of mutagenic/genotoxic effect of PM0.5 collected in five italian towns in two seasons: results of the MAPEC_LIFE study (LIFE12 ENV/IT/000614)

Marco Verani Annalaura Carducci Beatrice Casini Gabriele Donzelli Giacomo Palomba

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Feasibility and reliability of a questionnaire for evaluation of the exposure to indoor and outdoor air pollutants, diet and physical activity in 6-8-year-old children.

PubMed (2015)

Claudia Zani Francesco Donato Sara Grioni Gaia Claudia Viviana Viola Elisabetta Ceretti

The MAPEC-Life project aims to study the biological effects of early exposure to air pollutants on the oral mucosa cells of school-age children in five Italian cities. A questionnaire was created to evaluate the association between outdoor and indoor airborne pollutants, lifestyle, diet and biomarker effects. The feasibility and reliability of the questionnaire were evaluated.

Cohen's kappa

Food frequency questionnaire

Calorie

Questionnaire

10.7416/ai.2015.2056

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Citations (11)

The assessment of WWTP performance: Towards a jigsaw puzzle evaluation?

Chemosphere (2015)

Matteo Papa Elisabetta Ceretti Gaia Claudia Viviana Viola Donatella Feretti Ilaria Zerbini

Ecotoxicity

Ames test

10.1016/j.chemosphere.2015.11.054

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Citations (36)

Valutazione della genotossicità/mutagenicità indotti dal PM0,5 di 5 città italiane in due stagioni: risultati dello studio MAPEC

Sara Bonetta Silvia Bonetta Elisabetta Ceretti Gaia Claudia Viviana Viola Ilaria Zerbini

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Republica da Mocambique. Serie geologica 1:250 000. Folha no. 1635 Milange

Robert J. Thomas Joachim Jacobs Louise Hollick Gaia Claudia Viviana Viola

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Intensity and type of physical activity and semen quality in healthy young men

Fertility and Sterility (2024)

Francesco Donato Matteo Rota Elisabetta Ceretti Gaia Claudia Viviana Viola Monica Marullo

Semen quality

10.1016/j.fertnstert.2024.08.323

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Voluminose masse addominali: Diagnosi differenziale e soluzione chirurgica adottata

Urologia Journal (1995)

M. Curti Giardina Gaia Claudia Viviana Viola F. Ocello F. Orestano

Masses involving the abdominal organs present the problem of differential diagnosis and the symptomatology can be extremely varied in relation to their manifestation. The authors report their experience in a few cases, showing that the histopathological examination often plays an important role in leading to a correct diagnosis.

Histopathological examination

10.1177/039156039506200424

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Riutilizzo delle scorie di acciaieria: valutazione dell’attività genotossica

D. Feretti S. Sorlini G. Piovani C. Alias L. Benassi

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