In IVCS strain mice with 4 day cycle, kept under the 14L, 10D lighting schedule (light phase from 5:00 am. to 7:00 pm.), the ovulation took place regularlly on every 4 day in the period be-tween 1:00 am. and 4:00 am. of the day of vaginal estrus. And the release of an enough quantity of ovulating hormone (LH) to cause ovulation occured through the period from 1:00 pm. to 5:00 pm. on the day of vaginal proestrous. These data was quite comparable to the rats of Wistar-Imamichi strain under the same lighting schedule.Although the rats showed the delay in ovulation for 24-hrs. by a single intraperitoneal injection of Nembutal (30 mg/kg) at 1:00 pm. of the proestrous day, the mice showed only a short delay (about 2 hrs.), but not 24-hrs-delay by the similar Nembutal treatment even with a much higher dosage (100 mg/kg). To extend duration of anesthetic state, additional injections of Nembutal (50 mg/kg/inj.) were performed at every 2 hrs., starting from 5:00 pm. of the proestrous day. In the mice given an additional injection at 5:00 pm., tubal ova were firstly found at 8:00 am. on the following morning. Unitil 9:00 pm. of the proestrous day when the last additional injection was made, with increase in numbers of additional injections, the delay in ovulation was proportionally prolonged for 2 hrs. per each injection. However, if the additional injections were extended to 11:00 pm. of the proestrous day or farther, the ovulation was completely blocked during the next day (the day of vaginal estrus), and showed 24-hrs-delay in ovulation.A similar result was obtained with the atropine treatment. Namely, a single subcutaneous injection of atropine (500 mg/kg) at 1:00 pm. of the proestrous day resulted in ovulation for a several hrs. but not for 24 hrs.It is assumed, therefore, that in the IVCS mice, a duration of the central excitation period, responsible for the LH-surge might last much longer than that in the rat.A short delay in ovulation, however, was seemed to be present also in the rat under a certain condition. As was already pointed out by EVERETT et al. (1950), two succesive injections of Nembu-tal at 1:00 pm. on the second day into the rat which had been blocked its ovulation in the first day, needed to get the delay in ovulation for 2 days. In the condition, when the supplemental injection at 5:00 pm. of the second day was omitted, the ovulation was delayed for about 3 hrs.-from the proper time of ovulation.
In order to observe the influences of ATP on the bone marrow thrombopoiesis, clinical tissue culture of bone marrow from normal guinea pigs, normal persons and patients with hypoplastic anemia was conducted. ATP solutions at various concentrations were added directly to the culture media and observations were carried out to see effect of ATP on the functions of megakaryocytes of bone marrow. As a result, it has been seen that by adding an optimal amount of ATP the functions of megakaryocytes were accelerated.
A family of five and six-bladed SRI-B propellers suitable for a high-speed ship, particularly from the standpoint of cavitation characteristics, has been developed. Preliminary studies on optimum shape of blade section were made with regard to cavitation characteristics, based on the pressure distributions of the corresponding two-dimensional wings, which were calculated by the lifting surface theory and from cavitation tests of the propellers in a uniform flow. Systematic open water tests have been carried out and the propeller performances are expressed as polynomials of advance coefficient and pitch ratio of propellers. From the results of open water tests design diagrams are evolved.
A 16-b digital signal processor (DSP) is described that realizes an 11.2-kb/s vector sum-excited linear predictive (VSELP) speech codec, chosen as the digital cellular standard in Japan. Power consumption of 70-mW at 3.5-V VDD is achieved by using a double-speed multiply-accumulate system, by improving logical and transistor circuits, and by using a 0.8- mu m double-metal-layer CMOS process and a low-VDD supply. The block diagram of this DSP is shown along with the mechanism of double-speed MAC operation.< >
Abstract In order to study the frequency of occurrence of Barnes' ventrolateral pyramidal tract, the lower parts of the medulla oblongata and the upper three cervical segments of the spinal cords of 210 adult Japanese were examined histologically. The tracts were encountered in 43 out of 210 cases (20.5 ± 2.8%); bilaterally in (7.6 ± 1.8%), and unilaterally in 27 (12.9 ± 2.3%) cases. Consequently the tracts were found to be present in 59 out of 420 sides (14.0 ± 1.7%). Sex diffierence was not statistically significant (χ 2 = 0.6, d.f. = 1, p > 0.25).
