Enrico Nastro Siniscalchi

University of Messina

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Francesco Saverio De Ponte

University of Messina

Luciano Catalfamo

University of Messina

Giacomo Oteri

University of Messina

Caterina Musolino

University of Messina

Alessandro Allegra

University of Messina

Gabriele Cervino

University of Messina

Giovanni Raffa

University of Messina

Marco Cicciù

University of Catania

Andrea Alonci

University of Messina

Salvatore Crimi

University of Catania

Cooperative Institutions

University of Messina

140

Azienda Ospedaliera Universitaria Policlinico "G. Martino"

Morpho (United States)

Sapienza University of Rome

Istituti di Ricovero e Cura a Carattere Scientifico

University of Catania

Centro Neurolesi Bonino Pulejo

Policlinico Universitario di Catania

Policlinico Umberto I

University of Palermo

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A Low-Cost Wireless Bite Force Measurement Device

Materials (2022)

Paolo De Pasquale Erasmo Rubino Daniele Borzelli Matteo Peditto Enrico Nastro Siniscalchi

Assessing maximum voluntary bite force is important to characterize the functional state of the masticatory system. Due to several factors affecting the estimation of the maximum bite force, a unique solution combining desirable features such as reliability, accuracy, precision, usability, and comfort is not available. The aim of the present study was to develop a low-cost bite force measurement device allowing for subject-specific customization, comfortable bite force expression, and reliable force estimation over time. The device was realized using an inexpensive load cell, two 3D printed ergonomic forks hosting reusable subject-specific silicone molds, a read-out system based on a low-cost microcontroller, and a wireless link to a personal computer. A simple model was used to estimate bite force taking into account individual morphology and device placement in the mouth. Measurement reliability, accuracy, and precision were assessed on a calibration dataset. A validation procedure on healthy participants was performed to assess the repeatability of the measurements over multiple repetitions and sessions. A 2% precision and 2% accuracy were achieved on measurements of forces in the physiological range of adult bite forces. Multiple recordings on healthy participants demonstrated good repeatability (coefficient of variation 11%) with no significant effect of repetition and session. The novel device provides an affordable and reliable solution for assessing maximum bite force that can be easily used to perform clinical evaluations in single sessions or in longitudinal studies.

Repeatability

Bite force quotient

Accuracy and precision

Load cell

Measurement device

10.3390/ma15114000

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Citations (5)

How to Avoid and Manage Mental Nerve Injury in Transoral Thyroidectomy.

PubMed (2019)

Daqi Zhang Fausto Famà Ettore Caruso Giulia Pinto Alessandro Pontin

Transoral endoscopic thyroidectomy by vestibular approach (TOETVA) represents an innovative and scarless technique for thyroid surgery. The procedure is conducted via a three-port technique at the oral vestibule using a 10mm port for the 30° endoscope and two additional 5mm ports for the dissecting and coagulating instruments. Patients meeting the following criteria can be considered as candidates for TOETVA: (a) an ultrasonographically (US) estimated thyroid diameter =10cm; (b) US-estimated gland volume =45mL; (c) nodule size =50mm; (d) presence of a benign tumor, such as a thyroid cyst or a single- or multinodular goiter; (e) Bethesda 3 and/or 4 categories, and (f) papillary microcar-cinoma without the evidence of metastasis. Beyond the classic complications of thyroid surgery, namely cervical hematoma, recurrent laryngeal nerve injury and hypoparathyroidism, novel consequences can occur as mental nerve (MN) injury. In this paper, leading experts in the field report on their current clinical experience with the TOETVA approach for thyroid gland surgery, with emphasis given to tips and tricks to avoid and manage MN injury.

Mental nerve

Endoscope

Nerve Injury

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Citations (13)

Clinical Significance of Diplopia and the Orthoptic Examination in Zygomatic Maxillary Complex Fractures

Journal of Craniofacial Surgery (2024)

Enrico Nastro Siniscalchi Giorgio Lo Giudice Alessandro Calvo R. Marino Paola Bonavolontà

Literature describes variable rates of diplopia of associated with zygomatic maxillary complex (ZMC) fractures (6% to 40%). The aim of this study was to retrospectively assess the prevalence of diplopia in ZMC fracture patients, the usefulness of the orthoptic evaluation compared with the clinical finger-tracking examination, and to seek possible relations of this symptom with clinical parameters. Data of patients attending the Maxillofacial Surgery Units of the University of Messina and University of Naples “Federico II”, between January 2012 and December 2022 were retrieved. Statistical analysis of positive versus negative diplopia at both the clinical examination and the orthoptic evaluation and subgroup analysis were performed. 320 patients were included in the analysis. 50 (15.6%) patients reported diplopia at the clinical examination, whereas 70 (21.9%) resulted positive at the orthoptic evaluation. Statistical analysis for every determinant and subgroup did not show statistical significance ( P >0.05). Performing routine preoperative orthoptic evaluation allowed an increase of 6.3% in positive reports. Although it seems that no basic clinical parameter can predict diplopia, results suggest that the orthoptic evaluation is superior in the assessment of this symptom. Clinical analysis was shown to be a moderate/low efficient test and should not be used as a decisional standard.

Orthoptics

Statistical Analysis

Clinical Significance

10.1097/scs.0000000000010356

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Letter to the Editor Regarding “A Staged Therapy for Internal Carotid Artery Dissection Caused by Vascular Eagle Syndrome”

World Neurosurgery (2020)

Enrico Nastro Siniscalchi Giovanni Raffa Antonino Germanò Francesco Saverio De Ponte

Neurovascular bundle

Carotid Artery Dissection

Stroke

10.1016/j.wneu.2019.10.057

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Citations (5)

Proposal for a new self-compiled questionnaire in patients affected by temporo-mandibular joint disorders (TMD).

Alessandro Agrillo Valerio Ramieri Cristiana Bianca Enrico Nastro Siniscalchi Fatone Fm

In this work, we propose a self-compiled questionnaire, for those patients showing dysfunctions of the temporomandibular joint. The questionnaire, composed by 33 closed multiple-choice questions, represents one of the steps in the diagnostic procedure, together with the clinical notes compiled by the medical specialist and with the other necessary diagnostic researches. It also has the purpose to make easier anamnesis and clinic procedure and gathering of all informations useful for a right clinical diagnosis, and so for an appropriate therapy.

Anamnesis

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Dynamic imaging in suspected Eagle syndrome

European Archives of Oto-Rhino-Laryngology (2019)

Enrico Nastro Siniscalchi

10.1007/s00405-019-05678-0

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Citations (11)

Maxillofacial and concomitant serious injuries: An eight-year single center experience

Chinese Journal of Traumatology (2017)

Fausto Famà Marco Cicciù Alessandro Sindoni Enrico Nastro Siniscalchi Roberto Falzea

Maxillofacial injuries are frequently associated with multiple trauma and can determine functional and aesthetic bad outcomes. The severity of maxillofacial injuries may be considerable and can divert clinicians' attention from other concomitant injuries which is less evident but potentially life-threatening. The aim of this study was to find out the concomitant injuries in patients referred to the Emergency Department (ED) of the University Hospital of Messina (North-East Sicily, Italy) for maxillofacial traumas.We retrospectively evaluated data of 240,833 patients admitted at the ED of the University Hospital of Messina from January 2008 to December 2015 because of maxillofacial injuries leading to hospitalization and surgical treatment. Patients who primarily received treatment care at different institutions, pediatric trauma patients and adult patients who were transferred in accordance with pre-existing agreements in case of paucity of beds were excluded. Finally we included 447 (0.2%) patients over the 8 years. Data were evaluated with emphasis on epidemiology (age, gender, mechanism of trauma), primary survey and abnormalities and pattern of trauma.The most frequent cause of maxillofacial trauma was road accidents (319 patients, 71.4%), among which motorcycle ones were prevalent. The maxillofacial injured who presented major lesions were 98 patients and minor lesions occurred in 349 patients; 443 (99.1%) patients underwent maxillofacial surgery, immediate or delayed depending on the severity of concomitant injuries (χ2 = 557.2, p < 0.0001). Five concomitant neglected lesions were found to be associated with severe maxillofacial traumas (χ2 = 17.13, p < 0.0001 vs minor lesions). All of the neglected lesions occurred in paucisymptomatic patients who showed painless abdomen, no hemodynamic instability, no signs of hematoma of anterior and posterior abdominal wall or other suspicious clinical signs and symptoms.Among the patients admitted firstly in other surgical wards different from the Maxillofacial Surgery Unit, diagnosis was more difficult, especially for blunt abdominal traumas, in which patients showed only vague and nonspecific symptoms concealing serious and life-threatening injuries. We recommend the routine use of whole body CT scan, when the maxillofacial injuries appear prevalent, mainly in patients affected by maxillofacial major lesions.

Concomitant

Trauma Center

10.1016/j.cjtee.2016.11.003

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Citations (73)

Titanium Miniplates

Journal of Craniofacial Surgery (2013)

Enrico Nastro Siniscalchi Luciano Catalfamo Alessandro Allegra Caterina Musolino Francesco Saverio De Ponte

Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a rare but potentially severe condition, and the etiopathology and risk factors are poorly defined. The American Association of Oral and Maxillofacial Surgeons position paper on BRONJ update 2009 remarks all the risk factors of developing BRONJ. Local anatomy such as lingual tori, mylohyoid ridge or palatal tori, and areas with thin mucosa overlying bony prominences represent some of these local factors. We have recently treated a patient presenting a mandibular osteonecrosis involving a rigid miniplate which had been placed 18 years ago during a surgical excision of a radicular cyst. The patient, a 70-year-old female, did not show any other risk factors which could expose her to BRONJ, such as cortisone therapy, head and neck radiotherapy, chemotherapy, periodontal disease, or other.

10.1097/scs.0b013e31826d07b9

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Citations (15)

Scanning electron microscopy study on mandibular human bone and immunofluorescence study on oral mucosa in patients treated with bisphosphonates

Italian Journal of Anatomy and Embryology (2012)

Giuseppina Cutroneo Antonio Centofanti Giovanna Vermiglio Enrico Nastro Siniscalchi Michele Runci

Bisphosphonates are stable analogues of pyrophosphate with a P-C-P structure and 2 side chains attached to the carbon atom. Intravenous bisphosphonates are primarily used and effective in the management of cancer-related conditions in the context of solid tumors, such as breast cancer, prostate cancer, and lung cancer. Moreover bisphosphonates are subministrated to patients with metabolic bone diseases such as osteoporosis and Paget disease. Bisphosphonate-associated osteonecrosis of the jaws (BONJ) is a really complication of intravenous bisphosphonate therapy in patients with cancer. It is common knowledge that the jaws have a greater blood supply than other bones and a fasterbone turnover rate, related both to their daily activity and presence of teeth which mandates daily bone remodeling around the periodontal ligament; moreover bisphosphonates toxicity to epithelial cells has been well documented. On this basis, the aim of this study is to evaluate the pathological changes of the mandibular bone and oral mucosa in patients treated with bisphosphonates, during osteoporosis treatment and during chemotherapy from solid cancer. In details we have analyzed, by immunohistochemical and scanning electron microscopic methods, intrasurgical biopsy of mandibular bone and of gingival mucosa in patients treated with bisphosphonates both intravenous and oral via after 24 and 36 months from assumption of drugs. Our results show in all patients great area demineralization bone mixed to normal bone, moreover in the demineralization bone it’s possible to observe numerous micro lacunae. In the correspondence samples of gingival epithelium we observe important lesions of histological structure and the disappearance of protein adhesion system cells to cells and cells to matrix. On this basis it is intriguing to speculate that the adverse effects of BP on oral epithelium may play a critical role in the initiation of BONJ an “outside-in” hypothesis.

Bone remodeling

Oral mucosa

10.13128/ijae-11959

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Frameless Stereotactic Radiosurgery for Treatment of Multiple Sclerosis–Related Trigeminal Neuralgia

World Neurosurgery (2017)

Alfredo Conti Antonio Pontoriero Giuseppe Iatì Felice Esposito Enrico Nastro Siniscalchi

Rhizotomy

Cyberknife

Trigeminal Nerve

Refractory (planetary science)

10.1016/j.wneu.2017.04.102

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Citations (30)