Quality of Life (QoL) is a consistent and powerful predictor that affects the out-come in end-stage renal disease (ESRD) patients on dialysis. This study was undertaken to identify the factors that might predict QoL scores among ESRD patients on hemodialysis (HD). The study was conducted at three HD units in Saudi Arabia from January 2007 to January 2008. We studied 100 HD patients (53 males and 47 females) and used the SF-36 and KDQoL-SF forms covering six domains of QoL, namely physical, emotional, social, illness impact, medical and financial satisfaction, and overall general health. The mean age of the study patients was 47.5 ± 13.8 years and the mean duration of dialysis was 77.2 ± 75.5 months. The QoL scores were 45.8 ± 17.1 for general health, 53.1 ± 32.0 for physical QoL, 50.5 ± 14.8 for emotional QoL, 54.9 ± 18.1 for social QoL, 46.5 ± 13.7 for illness impact, and 45.9 ± 12.2 for the medical and financial domain. The total QoL score was 49.5 ± 13.7. The male patients had statistically significantly reduced QoL and younger patients had better QoL scores. The QoL scores revealed a decreasing trend with decreasing level of education; they were elevated among employed patients. Multiple linear regression analysis demonstrated that age, dialysis duration, and male sex were negative predictors of QoL score. We conclude from our study that QoL is reduced in all the health domains of HD patients. Older age, male gender, unemployment, and duration of dialysis adversely affected the QoL scores. Adequate management of some of these factors could influence patient outcomes.
Quality of life (QoL) in end-stage renal disease (ESRD) patients is an important outcome for both physicians and patients in selecting dialysis modality. We conducted a comparison between regular maintenance hemodiaylsis and regular peritoneal dialysis patients in two tertiary referral hospitals in King Saud University in Saudi Arabia. We hypothesize that there might be cultural and socioeconomic factors modifying QoL in dialysis patients.
Aspects of quality of life (QoL) is considering the important indicator to reflect the significant problems for patients receiving hemodiodalys (HD) therapy. To assess the quality of life using kidney disease quality of lif sort form (KDQOL TM) of patient on HD. The cross-sectional study was carried out in security forces hospital-Saudi Arabia-dialysis unit, from July 2010 to March 2011, All prevalent chronic HD patient (N = 50), mean age 46.6(14.0) years on maintenance hemodiodialys duration ranged from −24 to +60 months. In the study sample the characteristics of patients on hemodiodialys therapy both sexes were represented in nearly with the mean age was 46.0 (14.0) year on maintenance hemodiodialysis duration ranged from −24 to +60 months and the caregivers were mostly female, Unemployed, housewife, with basic/intermediate level of education. They were mostly married, and have children. With an age 52.0% more the 40 of years According to KDQOL-SF, the mean of overall QOL was 56.6, the effects of kidney disease score was 58.0(18.9), sleep score was 60.5(22.4), work status score was 46.0(38.9)and pain score was 52.0(28.2) Furthermore the overall QoL score statistically significant positive correlation with level of education (r = 465) an negative correlation with the patients’ age (r = 439). Our results suggest that more than half of these patients might be considered for rehabilitation program including exercise program and counseling to improve overall QoL of HD patients in Saudi Arabia.
The Dialysis Outcomes and Practice Patterns Study (DOPPS) is an international prospective cohort study of the relationships between hemodialysis (HD) care practices and HD patient outcomes. The DOPPS began in 1996, in the United States, and has since expanded to 21 countries, collecting detailed data from >75,000 HD patients, with >200 scientific publications, focused on describing HD practices associated with improved HD patient outcomes. The goal of DOPPS is to help HD patients "live better and live longer." Starting in 2012, the DOPPS was able to expand to all six of the Gulf Cooperation Council (GCC) countries, namely, Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and the United Arab Emirates. The DOPPS study design consists of selecting HD facilities for study participation in each country to represent the different types of HD facilities and geographic regions within each GCC country. Within each study site, HD patients were randomly selected for detailed data collection to represent the HD practices within each participating HD facility. Altogether, 41 HD facilities have participated in the GCC-DOPPS Phase 5 study including 20 facilities from Saudi Arabia, nine from the United Arab Emirates, four each from Kuwait and Oman, two from Qatar, and one from Bahrain. Herein, we provide a detailed description of the study design and methods, data collection, study management, scientific investigator oversight and guidance, and study governance and support for the GCCDOPPS Phase 5 study.
Background The prospective Dialysis Outcomes and Practice Patterns Study (DOPPS) has collected data since 2012 in all six Gulf Cooperation Council (GCC) countries (Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, and United Arab Emirates). We report the relationship of PTH with mortality in this largest GCC cohort of patients on hemodialysis studied to date. Methods Data were from randomly selected national samples of hemodialysis facilities in GCC-DOPPS phases 5 and 6 (2012–2018). PTH descriptive findings and case mix–adjusted PTH/mortality Cox regression analyses were based on 1825 and 1422 randomly selected patients on hemodialysis, respectively. Results Mean patient age was 55 years (median dialysis vintage, 2.1 years). Median PTH ranged from 259 pg/ml (UAE) to 437 pg/ml (Kuwait), with 22% having PTH <150 pg/ml, 24% with PTH of 150–300 pg/ml, 34% with PTH 301–700 pg/ml, and 20% with PTH >700 pg/ml. Patients with PTH >700 pg/ml were younger; on dialysis longer; less likely to be diabetic; have urine >200 ml/d; be prescribed 3.5 mEq/L dialysate calcium; had higher mean serum creatinine and phosphate levels; lower white blood cell counts; and more likely to be prescribed cinacalcet, phosphate binders, or IV vitamin D. A U-shaped PTH/mortality relationship was observed with more than two- and 1.5-fold higher adjusted HR of death at PTH >700 pg/ml and <300 pg/ml, respectively, compared with PTH of 301–450 pg/ml. Conclusions Secondary hyperparathyroidism is highly prevalent among GCC patients on hemodialysis, with a strong U-shaped PTH/mortality relationship seen at PTH <300 and >450 pg/ml. Future studies are encouraged for further understanding this PTH/mortality pattern in relationship to unique aspects of the GCC hemodialysis population.
The occurrence of hepatitis C virus (HCV) infection amongst chronic renal failure (CRF) patients in our Nephrology Unit was investigated over a period of 1 year. A total of 71 patients was studied comprising 26 chronic haemodialysis (CHD) patients, 6 acute haemodialysis patients, 4 peritoneal dialysis patients and 35 CRF patients not on dialysis. Patients were screened before and after haemodialysis, and their baseline and postdialysis values of liver enzymes were determined. Eleven (15.5%) of the total 71 patients were HCV antibody positive. Analysis of the individual patient groups showed that 8 (30.7%) of the 26 CHD patients were positive for HCV. Our data showed a statistically significant relationship between seroconversion and duration of dialysis (p < 0.05). A high statistically significant (p < 0.0001) correlation was observed between the HCV antibodies and CRF. The relative risk of hepatitis C was about 22 times greater for those with CRF compared with the normal controls, which makes CRF an important risk factor. A high proportion of the HCV seroconverters had elevated liver enzyme (serum glutamic pyruvic transaminase). The data presented show a positive correlation between HCV seroconversion, CRF, duration on dialysis and elevated serum liver enzymes.
Background: Quality of life (QoL) infl uences the morbidity and mortality in End-Stage Kidney Disease (ESKD) patients on dialysis. Identifi cation of the factors that infl uence QoL in patients receiving peritoneal dialysis can help in their management to improve the QoL and outcomes for these patients. Aim of the study: This study was carried out to determine the factors that could predict QoL scores among ESKD patients on peritoneal dialysis. Methods: This cross-sectional study was conducted in Hemodialysis Units of King Khalid University, King Saud University, and Security Forces Hospitals, Riyadh, Saudi Arabia. 100 peritoneal dialysis patients fi lled the SF-36 questionnaire form covering 6 domains of QoL, and overall general health. Data analysis was done in terms of scores from 0-100 in each domain. Higher scores indicate better QoL. Results: The study included 43 males and 57 females. Mean age was 57.0±13.5 years. The duration of dialysis was 34.1±26.9 months. The QoL scores [mean(SD)] were as follows: general health 58.0(9.8), physical role 47.7(23.6), emotional role 61.9(13.5), social function 68(17.5), illness impact 63.9(9.5), and medical and fi nancial satisfaction 68.4(13), with a total of 61.3(12.4). QoL scores had a statistically signifi cantly decreasing trend with increasing age (p=0.001). Unemployed and illiterate patients had lower QoL scores (p=0.03 and p=0.001). No statistically signifi cant relationship could be revealed between QoL score and the duration of dialysis. Conclusion: The QoL of peritoneal dialysis patients is negatively related to age and is affected by educational level and job status. Special care and support is needed for these patients to ameliorate their QoL, and improve their outcome.
