Sajid Naeem

Maulana Mukhtar Ahmad Nadvi Technical Campus

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Dilawar Husain

Maulana Mukhtar Ahmad Nadvi Technical Campus

Arun V. Patil

G.S. Science, Arts And Commerce College

Khezran Qamar

CMH Lahore Medical College and Institute of Dentistry

Yingmei Zhang

Lanzhou University

Yongmei Qi

Lanzhou University

AV Patil

G.S. Science, Arts And Commerce College

Shameem Ahmad

Maulana Mukhtar Ahmad Nadvi Technical Campus

Md Tanwir Alam

Maulana Mukhtar Ahmad Nadvi Technical Campus

Irfan Ahmed Shaikh

Sindh Agriculture University

Syed Hammad Azeem Rizvi

CMH Lahore Medical College and Institute of Dentistry

Cooperative Institutions

Lanzhou University

CMH Lahore Medical College and Institute of Dentistry

G.S. Science, Arts And Commerce College

Maulana Mukhtar Ahmad Nadvi Technical Campus

University of the Punjab

Savitribai Phule Pune University

National University of Medical Sciences

Qingdao University

University of Veterinary and Animal Sciences

Henan Normal University

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Comparison Of Solubility And Water Sorption Of Two Different Soft Lining Material.

PubMed (2018)

Gotam Das Maimuna Khokhar Sajid Naeem Reehana Baloch

Soft denture lining materials play a very important role in Removable Prosthodontics because of their ability to provide a cushioning effect for maintaining the health of traumatized, swollen and deformed mucosa through absorption and equal redistribution of stresses over the entire area covered by denture, thus eliminating the distortion of oral mucosa. The objective of this investigation is to quantify and relate the mean solubility and water sorption of acrylic resin based permanent soft liner with a silicone based permanent soft liner.Two different permanent soft denture liners, i.e., acrylic and silicone based are selected for this study, 30 samples of each material are prepared in the form of circular disks of the 30 disks, and three subgroups of ten disks each are made for the two materials. Initially the processed disks will be weighed 3 times daily with an analytical balance until a constant weight is achieved. This initial weight of each specimen is denoted by W1. Each subgroup of 10 specimens is immersed in 250 ml of 37 °C distilled water in a sealed polyethylene container. First subgroup is tested after 1 week, second after 4 weeks and third after 6 weeks of immersion.Ever soft has higher solubility (1.67mg/cm2 ±0.26 mg/cm2laboratory-processed) and sorption (0.84 mg/cm2 ±0.35 mg/cm2laboratory-processed) than Molloplast B (0.40 mg/cm2 ±0.08 mg/cm2solubility and 0.27 mg/cm2 ±0.16 mg/cm2 sorption) after 6 weeks of immersion.It is therefore concluded that Molloplast B may provide better clinical success based on its lower solubility and water sorption.

Distilled water

Immersion

Acrylic resin

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Label-free proteomic analysis of intestinal mucosa proteins in common carp ( Cyprinus carpio ) infected with Aeromonas hydrophila

Fish & Shellfish Immunology (2017)

Guilan Di Hui Li Chao Zhang Yanjing Zhao Chuanjiang Zhou

Proteome

Common carp

10.1016/j.fsi.2017.04.025

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The role of endoplasmic reticulum stress in lead (Pb)-induced mitophagy of HEK293 cells

Toxicology and Industrial Health (2020)

Ke Gao Chengfei Zhang Yihong Tian Sajid Naeem Yingmei Zhang

It is well-documented that lead (Pb) toxicity can affect almost all systems in living organisms. It can induce selective autophagy of mitochondria (mitophagy) by triggering reactive oxygen species production. Emerging evidence has suggested that Pb-induced autophagy can also be activated by the endoplasmic reticulum (ER) stress pathway. However, the interplay between ER stress and mitophagy remains to be elucidated. In this study, human embryonic kidney HEK293 cells were employed to investigate the role of ER stress in Pb-induced mitophagy. The results showed that the cell viability was decreased and cell damage was induced after exposure to Pb (0, 0.5, 1, 2, and 4 mM) for 24 h in a dose-dependent manner. Moreover, the expression of LC3-Ⅱ was significantly increased, and the expression of HSP60 was dramatically decreased after exposure to 1 mM and 2 mM Pb, indicating the induction of mitophagy following Pb exposure. Meanwhile, the expressions of activating transcription factor 6, inositol-requiring protein-1α, CCAAT/enhancer binding protein homologous protein, and glucose-regulated protein 78 were dramatically increased after Pb treatment, signifying the initiation of ER stress. Notably, the mitophagic effect was significantly compromised when ER stress was inhibited by 0.5 mM 4-phenylbutyrate, which was evidenced by lesser decreases in HSP60 expression and level of LC3-Ⅱ, suggesting Pb-induced mitophagy may be activated by the ER stress. Taken together, these findings provide a better understanding of Pb toxicity and suggest that Pb-induced ER stress may play a regulatory role in the upstream of mitophagy.

Viability assay

10.1177/0748233720971882

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Recent advances in paper (cellulose)-based energy storage devices: a review

Energy Storage and Saving (2024)

Darshana A. Minde Somnath A. Wankhede Sajid Naeem Anil B. Patil Vikas V. Deshmane

10.1016/j.enss.2024.11.005

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Evaluating vibrating line location with respect to palatine fovea in various soft palate types

M. Aamir Ghafoor Chaudhary Syed Hammad Azeem Rizvi Afsheen Zakir Faiza Awais Noor Fatima

Aim: To determine the frequency of the location of vibrating line in relation to palatine fovea in Class I, II and III soft palate types among patients at Islamic International Dental College, Islamabad. Study design: A cross-sectional observational study Place and duration: Prosthodontic Dept of Islamic International Dental College, Riphah International University, from 2nd October 2021 till 2nd January 2022. Methodology: A total of 200 subjects were selected and clinically examined for various locations of vibrating line with respect to palatine fovea in soft palate types (I, II, III). Phonation method ‘Ah’ was used to locate vibrating line location. Results: The vibrating line location was anterior to palatine fovea in 72.7%, 64.1%, 50% of subjects with Class I, II, III soft palate. 16.5%, 25.6%, 22.7% subjects had vibrating line locating at fovea palatine in Class I, II, III soft palate types. Least observed location was the posterior location of vibrating line; 10.8%,10.3% 27.3% in all soft palate types (class I, II, III). In-significant association with age, gender and soft palate types was seen with location of vibrating line. Conclusion: The vibrating line was located predominantly anterior to palatine fovea in all three soft palate types. Keywords: Dentures, Post dam area, Palatine Fovea, Retention, Soft Palate Contours, Vibrating line.

Soft palate

10.53350/pjmhs22168178

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Investigating the electrical and thermal properties of Cu and Al-doped ZnO thick films using the screen-printing technique for thermal resistance applications

Journal of the Indian Chemical Society (2024)

Sajid Naeem Dilawar Husain Shameem Ahmad Fahim Faisal Yakub Ansari

Screen printing

10.1016/j.jics.2024.101292

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The toxic effects of chlorophenols and associated mechanisms in fish

Aquatic Toxicology (2017)

Tingting Ge Jiangyuan Han Yongmei Qi Xueyan Gu Lin Ma

Toxicant

10.1016/j.aquatox.2017.01.005

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Citations (159)

Carbon Footprint and Economic Assessment of LED Bulbs Recycling

Environmental footprints and eco-design of products and processes (2023)

Mohammed Salman Baig Dilawar Husain Shameem Ahmad Fahad Bilal Faheem Ansari

Tonne

Carbon Footprint

Incandescent light bulb

10.1007/978-981-19-8323-8_3

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Prevalence and Pattern of Tori among Edentulous patients of Dental College Islamabad

M. Aamir Ghafoor Chaudhary Mohsin Fazal Ushna Malik Fatima Nasir Cheema Muaz Ali Rizvi

Aim: To find out the prevalence and patterns of tori in edentulous patients and determine their association with gender and age. Study design: A cross-sectional observational study. Place and duration: Prosthodontic Department of Islamic International Dental College, Islamabad from 1st September 2021 to 1st December 2021. Methodology: A total of 165 edentulous patients of both genders were selected using non-probability purposive sampling. After collecting demographic data, intra-oral examination was carried out. Maxillary and mandibular stone casts were made after taking alginate impressions. Sharp graphite pencil was used to mark torus mandibularis and torus palatinus and the stone casts were carefully analyzed for size, shape and location of tori. Results: Total prevalence of tori in present study was 11.5%. 7.7% males and 14.9% female patients reported having tori. No gender association with tori existence found; p>0.05. Maximum number of tori reported in age group 71-80 years (21.4%). Chi square test showed association of tori presence with age; p <0.05. The flat and spindle shaped tori were (1.2%) whereas lobular and nodular shaped accounted for 1(0.6%) torus palatinus. The prevalence of small sized tori was mostly reported (7.9%). Unilateral single tori were frequently found (6.7%). Conclusion: The prevalence of tori occurrence in edentulous patients is low. There was no significant difference in the prevalence of tori among male and female patients however tori exitance increases with increasing age. Key words: Torus Palatinus, Torus Mandibularis, frequency, edentulous, prevalence.

10.53350/pjmhs22167163

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Myricetin: targeting signaling networks in cancer and its implication in chemotherapy

Cancer Cell International (2022)

Zeeshan Javed Khushbukhat Khan Jesús Herrera‐Bravo Sajid Naeem Muhammad Javed Iqbal

Abstract The gaps between the complex nature of cancer and therapeutics have been narrowed down due to extensive research in molecular oncology. Despite gathering massive insight into the mysteries of tumor heterogeneity and the molecular framework of tumor cells, therapy resistance and adverse side effects of current therapeutic remain the major challenge. This has shifted the attention towards therapeutics with less toxicity and high efficacy. Myricetin a natural flavonoid has been under the spotlight for its anti-cancer, anti-oxidant, and anti-inflammatory properties. The cutting-edge molecular techniques have shed light on the interplay between myricetin and dysregulated signaling cascades in cancer progression, invasion, and metastasis. However, there are limited data available regarding the nano-delivery platforms composed of myricetin in cancer. In this review, we have provided a comprehensive detail of myricetin-mediated regulation of different cellular pathways, its implications in cancer prevention, preclinical and clinical trials, and its current available nano-formulations for the treatment of various cancers.

Myricetin

Cancer Therapy

10.1186/s12935-022-02663-2

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Citations (59)